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151.
Janneke AL van Kempen Sarah HM Robben Sytse U Zuidema Marcel GM Olde Rikkert René JF Melis Henk J Schers 《The British journal of general practice》2012,62(601):e554-e560
Background
A number of studies have examined the effects of home visits and showed inconsistent results on physical functioning, institutionalisation, and mortality. Despite continuing interest from professionals in home visits for older people, reports on older people’s needs and preferences for such visits are scarce.Aim
This qualitative study aims to explore the views and needs of community-dwelling frail older people concerning home visits.Design and setting
A qualitative study including interviews with frail older persons and their informal caregivers living in the area of Nijmegen, the Netherlands.Method
Semi-structured interviews were conducted with frail older people and informal caregivers. A grounded theory approach was used for data-analysis.Results
Eleven frail older people and 11 informal caregivers were included. Most participants emphasised the importance of home visits for frail older people. They felt that it would give older people the personal attention they used to receive from GPs but miss nowadays. Most stated that this would give them more trust in GPs. Participants stated that trust is one of the most important factors in a good patient–professional relationship. Further, participants preferred home visits to focus on the psychosocial context of the patient. They stated that more knowledge of the psychosocial context and a good patient–professional relationship would enable the professional to provide better and more patient-centred care.Conclusion
Patients’ expectations of home visits are quite different from the actual purpose of home visiting programmes; that is, care and wellbeing versus cure and prevention. This difference may partly explain why the effectiveness of home visits remains controversial. Future studies on home visits should involve patients in the development of home visiting programmes. 相似文献152.
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155.
Reply to “Letter to the Editor Concerning the Article‐Impact of Surgery on Survival in Stage IV Breast Cancer” 下载免费PDF全文
156.
K. AL Qahtani A.F. Alkhudhayri T. Islam K. Al Mufargi W. Al Shakweer F. Otaibi 《Saudi Journal of Ophthalmology》2019,33(1)
Unicystic Ameloblastoma (UA) is a rare variant of ameloblastoma which is an odontogenic epithelial neoplasm, typically affecting mandibular ramus. Maxillary ameloblastoma is a rare entity with a more disastrous consequence. Although extremely rare, their highly recurrent and locally aggressive behavior can lead to invasion of vital structures surrounding maxilla (orbit, cranium) even after several years of conservative surgical management (limited resection, curettage). We report a case of 16-year-old girl presenting with proptosis of left eye, UA left maxilla, who was treated initially with limited resection (enucleation) and curettage and the lesion recurred after two years with a more aggressive behavior, causing destruction floor of orbit. To this date there are only 23 documented cases of orbital invasion and only three of the reports are in ophthalmic literature. The ophthalmologists need to be aware of this type of rare lesion presenting as proptosis. 相似文献
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158.
标题 a)口服左旋-Sotatol治疗心肌梗死后左室功能不全患者生存研究(SWORD):试验依据、设计和方法 b)右旋-Sotatol对亚急性和陈旧性心肌梗死后左室功能不全患者病死率的影响研究作者 WaldoAL,CammAJ,deruyterH,等a)AmJCardiol,1995,75:1023~1027b)Lancet,1996,348:7~12 研究疾病:充血性心力衰竭。目的:右旋-Sotatol为一种具有专一性钾通道阻滞作用的抗心律失常药物。本研究将对其降低心肌梗死后左室功能不全… 相似文献
159.
H4 acetylation, XIST RNA and replication timing are coincident and define x;autosome boundaries in two abnormal X chromosomes 总被引:3,自引:1,他引:2
The inactive X (Xi) differs from its active homologue (Xa) in a number of
ways, including increased methylation of CpG islands, replication late in S
phase, underacetylation of histone H4 and association with XIST RNA. Global
changes in DNA methylation occur relatively late in development, but the
other properties all change during or shortly after the establishment of Xi
and may play a role in the mechanism by which an inactive chromatin
conformation spreads across most of the chromosome. In the present report,
we use two human X;autosome translocation chromosomes to study the
spreading of inactive X chromatin across X;autosome boundaries. In one of
these chromosomes, t(X;6), Xp distal to p11.2 is replaced by 6p21.1-6pter
and, in the other, ins(X;16), a small fragment derived from 16p13 is
inserted into the distal third of Xq. In lymphoid cells from patients
carrying these translocations in an unbalanced form, Xi was shown by HUMARA
assay to be derived exclusively [t(X:6)] or predominantly [ins (X;16)] from
the derived X chromosome. We used a combination of immunolabelling and
RNA/DNA fluorescence in situ hybridization to define the distribution of
XIST RNA, deacetylated H4 and late-replicating DNA across the two derived X
chromosomes in inactive form. Within the limits of the cytogenetic
techniques employed, the results show complete coincidence of these three
parameters, with all three being excluded from the autosomal component of
the derived X chromosome.
相似文献
160.