全文获取类型
收费全文 | 365篇 |
免费 | 19篇 |
国内免费 | 20篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 12篇 |
妇产科学 | 10篇 |
基础医学 | 41篇 |
口腔科学 | 11篇 |
临床医学 | 27篇 |
内科学 | 57篇 |
皮肤病学 | 5篇 |
神经病学 | 12篇 |
特种医学 | 158篇 |
外科学 | 23篇 |
综合类 | 3篇 |
预防医学 | 6篇 |
眼科学 | 1篇 |
药学 | 24篇 |
肿瘤学 | 13篇 |
出版年
2020年 | 1篇 |
2019年 | 3篇 |
2018年 | 6篇 |
2017年 | 4篇 |
2016年 | 12篇 |
2015年 | 14篇 |
2014年 | 12篇 |
2013年 | 7篇 |
2012年 | 6篇 |
2011年 | 10篇 |
2010年 | 9篇 |
2009年 | 17篇 |
2008年 | 24篇 |
2007年 | 34篇 |
2006年 | 12篇 |
2005年 | 15篇 |
2004年 | 10篇 |
2003年 | 6篇 |
2002年 | 13篇 |
2001年 | 15篇 |
2000年 | 9篇 |
1999年 | 11篇 |
1998年 | 25篇 |
1997年 | 15篇 |
1996年 | 7篇 |
1995年 | 10篇 |
1994年 | 10篇 |
1993年 | 9篇 |
1991年 | 7篇 |
1990年 | 1篇 |
1989年 | 10篇 |
1988年 | 9篇 |
1987年 | 6篇 |
1986年 | 9篇 |
1985年 | 6篇 |
1984年 | 6篇 |
1983年 | 2篇 |
1982年 | 4篇 |
1981年 | 3篇 |
1980年 | 4篇 |
1977年 | 2篇 |
1976年 | 4篇 |
1975年 | 4篇 |
1969年 | 1篇 |
排序方式: 共有404条查询结果,搜索用时 0 毫秒
71.
72.
LG Hamburg 《MedR Medizinrecht》2001,19(1):46-46
Ohne Zusammenfassung 相似文献
73.
LG Bochum 《MedR Medizinrecht》2009,27(2):95-98
Zusammenfassung Die Geltendmachung von Schadensersatz gegen einen Sachverst?ndigen gem. § 839a BGB setzt
eine detaillierte Auseinandersetzung mit dem Inhalt des Gutachtens voraus und erfordert einen substantiierten
Sachvortrag zu der vorgetragenen Behauptung einer vors?tzlichen bzw. grob fahrl?ssigen Erstattung
eines unrichtigen Gutachtens. Lediglich subjektive Zweifel an der Richtigkeit des Gutachtens begründen
noch keinen Anspruch. (Leitsatz der Bearbeiterin) 相似文献
74.
A patient with plasma cell myeloma producing only Bence Jones lambda protein was found to have pale intranuclear inclusions in the majority of the bone marrow plasma cells. These inclusions, previously undescribed in myeloma patients producing only Bence Jones protein, contained Bence Jones lambda protein, were non-electron dense, bound by a single membrane, and contained no cytoplasmic structures. Intracytoplasmic inclusions were not present, and the perinuclear cistern was not dilated. Thus, the inclusions may represent intranuclear protein synthesis with anomalous release in the abnormal cells. 相似文献
75.
76.
Grüntzig balloon catheters were used to dilate ten esophageal strictures in eight infants and children. Five infants who had anastomotic strictures following esophageal atresia repair gained complete resolution of their strictures, usually after one or two dilatations. Three older children who had strictures following esophageal re-operation or reconstruction required longer courses of dilatations to achieve consistent esophageal patency. The technique failed in two chronic strictures of two and one-half and nine years' duration. Balloon catheter dilatation, begun in the early postoperative period, is a safe, effective method for dilating esophageal strictures. 相似文献
77.
The regulation of hemopoiesis in long-term bone marrow cultures. II. Stimulation and inhibition of stem cell proliferation 总被引:6,自引:1,他引:6
The isolation of a DNA synthesis inhibitor (NBME fraction IV) and stimulator (RBME fraction III) specific for the hemopoietic stem cell (CFU-s) from freshly isolated normal adult and regenerating murine bone marrow, respectively, has been well documented. We have utilized long- term liquid bone marrow cultures in a further analysis of the role of these factors in the regulation of CFU-s proliferation. Our results show that shortly after feeding, at a time when the cultured CFU-s are actively proliferating, high levels of the hemopoietic stem cell proliferation stimulator fraction III can be isolated from the culture medium. In contrast, the presence of essentially noncycling CFU-s found in cultures fed 8-10 days previously correlates with high levels of the hemopoietic stem cell inhibitor fraction IV. These results suggest that a certain balance between these factors determines CFU-s proliferation in the long-term cultures. In support of this, DNA synthesis in actively cycling CFU-s in the long-term cultures is inhibited for at least 3 days by the addition of excess NBME fraction IV (inhibitor). Furthermore, DNA synthesis in noncycling cultured CFU-s is stimulated for at least 5 days by the addition of RBME fraction III (stimulator). 相似文献
78.
Percutaneous angioplasty in clinical management of renovascular hypertension: initial and long-term results 总被引:1,自引:0,他引:1
Martin LG; Price RB; Casarella WJ; Sones PJ; Wells JO Jr; Zellmer RA; Chuang VP; Silbiger ML Jr; Berkman WA 《Radiology》1985,155(3):629-633
Between January 1980 and July 1983, percutaneous transluminal angioplasty was attempted on 137 stenotic renal arteries in 100 patients. At termination of follow-up studies (3-39 months, mean of 16 months), 70% of those treated for hypertension had benefited from the procedure. Stenosis secondary to fibromuscular dysplasia responded better than stenosis from arteriosclerosis (85% and 65% of the patients, respectively). Benefit was minimal for those with stenosis of the renal artery ostium or renal insufficiency. Determining levels of renal vein renin before angioplasty is helpful in selecting patients; following angioplasty, this has considerable significance in predicting the success of the procedure. 相似文献
79.
80.
Effects of steroid hormones and antisteroids on alkaline phosphatase activity in human endometrial cancer cells (Ishikawa line) 总被引:8,自引:0,他引:8
Alkaline phosphatase activity in human endometrial cancer cells of the estrogen-responsive Ishikawa line was markedly stimulated (3-20-fold in 4 days) by estrogens, 5 alpha-dihydrotestosterone, and dehydroepiandrosterone but not by testosterone, medroxyprogesterone acetate, glucocorticoids, several peptide hormones, prostaglandins, or growth factors. Maximum responses to estradiol were obtained at concentrations between 10(-9) and 10(-7) M; at 10(-8) M estradiol, the highest activity was reached 48-72 h after addition of the hormone. A linear relationship between enzyme activity at 48 h and the length of exposure to the hormone was observed. Dibutyryl cyclic guanosine 3':5'-monophosphate, but not dibutyryl cyclic adenosine 3':5'-monophosphate enhanced alkaline phosphatase activity and acted synergistically with estradiol. trans-4-Monohydroxytamoxifen completely antagonized the stimulatory effect of estradiol and had no agonistic activity. Dihydrotestosterone and dehydroepiandrosterone appear to exert their effects, at least in part, by interacting with estrogen receptors, since the simultaneous presence in the medium of monohydroxytamoxifen abolished their influence on alkaline phosphatase activity. The specific antiandrogen monohydroxyflutamide partially antagonized the effect of these hormones, suggesting that their action involved androgenic mechanisms as well. Exposure to elevated temperature and to specific inhibitors identified alkaline phosphatase of Ishikawa cells as a placental-type isoenzyme, thus contrasting with the nonplacental type found in glandular epithelial cells of normal endometrium and in another human endometrial cancer cell line, HEC-50. This study extends our previous observations of estrogen responsiveness in the Ishikawa cell line. In addition to the previously reported stimulatory effects on growth and progesterone receptor levels, we are now describing the stimulation by estrogens and C19 steroids of an enzyme, alkaline phosphatase, which can be used as a convenient end point to examine mechanisms of hormonal action. 相似文献