全文获取类型
收费全文 | 3175篇 |
免费 | 144篇 |
国内免费 | 18篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 27篇 |
妇产科学 | 18篇 |
基础医学 | 396篇 |
口腔科学 | 47篇 |
临床医学 | 218篇 |
内科学 | 751篇 |
皮肤病学 | 206篇 |
神经病学 | 155篇 |
特种医学 | 451篇 |
外科学 | 432篇 |
综合类 | 12篇 |
预防医学 | 45篇 |
眼科学 | 11篇 |
药学 | 138篇 |
中国医学 | 8篇 |
肿瘤学 | 415篇 |
出版年
2023年 | 13篇 |
2022年 | 30篇 |
2021年 | 56篇 |
2020年 | 39篇 |
2019年 | 48篇 |
2018年 | 62篇 |
2017年 | 60篇 |
2016年 | 82篇 |
2015年 | 83篇 |
2014年 | 122篇 |
2013年 | 139篇 |
2012年 | 177篇 |
2011年 | 237篇 |
2010年 | 117篇 |
2009年 | 89篇 |
2008年 | 191篇 |
2007年 | 240篇 |
2006年 | 216篇 |
2005年 | 219篇 |
2004年 | 213篇 |
2003年 | 212篇 |
2002年 | 192篇 |
2001年 | 60篇 |
2000年 | 37篇 |
1999年 | 40篇 |
1998年 | 35篇 |
1997年 | 43篇 |
1996年 | 40篇 |
1995年 | 29篇 |
1994年 | 24篇 |
1993年 | 23篇 |
1992年 | 24篇 |
1991年 | 17篇 |
1990年 | 13篇 |
1989年 | 23篇 |
1988年 | 11篇 |
1987年 | 8篇 |
1986年 | 11篇 |
1985年 | 9篇 |
1984年 | 12篇 |
1983年 | 8篇 |
1982年 | 7篇 |
1981年 | 7篇 |
1980年 | 5篇 |
1979年 | 2篇 |
1978年 | 2篇 |
1977年 | 3篇 |
1976年 | 3篇 |
1974年 | 1篇 |
1972年 | 1篇 |
排序方式: 共有3337条查询结果,搜索用时 0 毫秒
31.
Hiroko Togawa Koichi Nakanishi Hironobu Mukaiyama Taketsugu Hama Yuko Shima Masaru Nakano Naoya Fujita Kazumoto Iijima Norishige Yoshikawa 《Pediatrics international》2013,55(2):229-231
Pierson syndrome (OMIM 609049) is typically characterized by congenital nephritic syndrome and peculiar ocular anomalies with microcoria. It is caused by mutations in LAMB2, which encodes laminin β2. Approximately 50 mutations of LAMB2 from approximately 40 unrelated families have been identified; however, most of them were from Western countries. Although three patients in Asia with mutations of LAMB2 have been reported, they were not typical cases. We report the first Japanese case of Pierson syndrome with proven causative LAMB2 mutations. She presented with congenital nephrotic syndrome and bilateral microcoria at birth, and developed end‐stage renal disease at 2 months of age. This is the first report of a typical case from Asia. LAMB2 analysis by direct sequencing revealed the compound heterozygous mutations c.3974_3975insA (p.N1325KfsX1331, maternal, novel) in exon 25 and c.4519C>T (p.Q1507X, paternal) in exon 27. The phenotype due to LAMB2 mutations appears to be similar between different ethnic groups. 相似文献
32.
Kanto S Sugawara J Masuda H Sasano H Arai Y Kyono K 《Fertility and sterility》2008,90(5):2010.e5-2010.e7
33.
34.
35.
Teruki Miyake Bunzo Matsuura Shinya Furukawa Toru Ishihara Osamu Yoshida Masumi Miyazaki Kyoko Watanebe Akihito Shiomi Hironobu Nakaguchi Yasunori Yamamoto Yohei Koizumi Yoshio Tokumoto Masashi Hirooka Eiji Takeshita Teru Kumagi Masanori Abe Yoshio Ikeda Takeru Iwata Yoichi Hiasa 《Journal of diabetes investigation.》2022,13(7):1245
IntroductionNonalcoholic fatty liver disease (NAFLD) is diagnosed after excluding other liver diseases. The pathogenesis of NAFLD when complicated by other liver diseases has not been established completely. Metabolic dysfunction‐associated fatty liver disease (MAFLD) involves more metabolic factors than NAFLD, regardless of complications with other diseases. This study aimed to clarify the effects of fatty liver occurring with metabolic disorders, such as MAFLD without diabetes mellitus (DM), on the development of DM.Materials and MethodsWe retrospectively assessed 9,459 participants who underwent two or more annual health check‐ups. The participants were divided into the MAFLD group (fatty liver disease with overweight/obesity or non‐overweight/obesity complicated by metabolic disorders), simple fatty liver group (fatty liver disease other than MAFLD group), metabolic disorder group (metabolic disorder without fatty liver disease), and normal group (all other participants).ResultsThe DM onset rates in the normal, simple fatty liver, metabolic disorder, and MAFLD groups were 0.51, 1.85, 2.52, and 7.36%, respectively. In the multivariate analysis, the MAFLD group showed a significantly higher risk of DM onset compared with other three groups (P < 0.01). Additionally, the risk of DM onset was significantly increased in fatty liver disease with overweight/obesity or pre‐diabetes (P < 0.01).ConclusionsFatty liver with metabolic disorders, such as MAFLD, can be used to identify patients with fatty liver disease who are at high risk of developing DM. Additionally, patients with fatty liver disease complicated with overweight/obesity or prediabetes are at an increased risk of DM onset and should receive more attention. 相似文献
36.
37.
Min Woo Lee Hyun Jeong Park Tae Wook Kang Jiwon Ryu Won-Chul Bang Bora Lee Eun Sun Lee Byung Ihn Choi 《Ultrasound in medicine & biology》2017,43(9):2024-2032
Factors affecting the registration error (RE) and motion of focal hepatic lesions (FHLs) in image fusion of real-time ultrasonography (US) with computed tomography (CT) images were prospectively assessed by focusing on respiratory movement and FHL location. Real-time US and pre-acquired CT images at end-inspiration were fused with FHLs for 103 patients. Three-dimensional US data containing FHLs were obtained during end-inspiratory/expiratory phases. Multivariate analysis revealed that diaphragm motion (p < 0.001), chronic liver disease (p = 0.02) and the absolute difference in distance between the FHL and the central portal vein (CPV) during respiration (p = 0.03) were the independent factors that revealed the maximum effect on RE. In contrast, diaphragm motion (p < 0.001) and distance between the FHL and CPV at inspiration (p = 0.036) revealed the maximum effect on FHL motion. In conclusion, RE and FHL motion are affected by the degree of respiratory movement and the location of the FHL. Therefore, image fusion with CT images should be used with caution if the degree of respiratory motion is significant or if the FHL is located at the periphery of the liver. 相似文献
38.
39.
40.