电子鼻咽喉镜下声带息肉切除术疗效分析(附128例报告)

目的探讨电子鼻咽喉镜下声带息肉切除术的临床疗效。方法应用Dr．Speech4．0嗓音分析软件，对128例在电子鼻咽喉镜下切除声带息肉患者的嗓音声学参数进行分析比较。结果128例声带息肉患者术后7～15天Jitter、Shimmer、NNE、HNR、SNR恢复正常，与术前相比，差异有非常显著性意义(P＜O．01)；而FD与术前相比，差异无显著,Sk(P＞O．05)。结论电子鼻咽喉镜下声带息肉切除术具有操作简单、安全、费用低、疗效好的优点。     

CONSTRUCTION，EXPRESSION AND BIOLOGICAL ASSESSMENT OF BPI23—Fcγ1 RECOMBINANT PROTEIN PROKARYOTIC EXPRESSION VECTOR

INTRODUCTIONGram－negativesepsis（GNS）andinfectiousshockarechallengestocliniciansbecauseofhighmortality（１）．Routineantibiotictherapydoesnotworkwellbe－causeoftheincreasingoccurrenceofresistantstrainsand（２）．Anti－lipopolysaccharide（LPS）monoclonal     

Enhancement of hepatic hemangiomas with levovist on coded harmonic angiographic ultrasonography.

OBJECTIVE: To evaluate the pattern of contrast enhancement with Levovist on coded harmonic angiographic ultrasonography of hepatic hemangiomas. METHODS: Twenty hemangiomas were evaluated with coded harmonic angiographic ultrasonography and a microbubble contrast agent. Verification of the diagnosis of a hemangioma was made by means of dynamic computed tomography (n = 8), dynamic magnetic resonance imaging (n = 1), radionuclide scanning (n = 6), or follow-up ultrasonography (n = 5). Ultrasonographic images were obtained before contrast agent administration and with a bolus injection of 2.5 g of a microbubble contrast agent (300 mg/mL Levovist; Schering AG, Berlin, Germany) every 10 to 15 seconds for 5 minutes. The contrast enhancement patterns of the 20 hemangiomas were assessed. RESULTS: The tumor diameters as measured on ultrasonography were 7 to 97 mm (mean, 26.7 mm). Of the 20 hemangiomas, peripheral globular enhancement with progressive centripetal fill-in was shown in 15 (75%), rimlike enhancement with progressive centripetal fill-in was shown in 2 (10%), and homogeneous enhancement was shown in 1 (5%). In the remaining 2 lesions (10%), the enhancement patterns could not be seen, because they were not found on coded harmonic angiographic ultrasonography. CONCLUSIONS: Coded harmonic angiographic ultrasonography with a microbubble contrast agent can depict the typical enhancement pattern in most hepatic hemangiomas.     

Otolaryngologic approach to the diagnosis and management of otitis media

Otitis media is a common childhood disease caused by multiple factors. Understanding the pathogenesis of otitis media is important in the diagnosis and management of it. The mode of therapy should be chosen depending on the type and stage of the disease. Treatment options available to an otolaryngologist include antibiotics, tympanocentesis, myringotomy and tympanostomy tube insertions, adenoidectomy with or without tonsillectomy, exploratory tympanotomy, atympanoplasty, and mastoidectomy.     

放射性核素人体全身骨显像及其定量分析

对12例非恶性肿瘤和骨性疾病患者(对照组）全身不同部位骨显像和43例恶性肿瘤患者的异常浓聚区进行定量分析。结果表明，对照组两侧相应部位的放射性比值（H值）约为1.05。若以阳性判断际准，43例恶性肿瘤患者138处病灶中有135处为阳性（9738％）。应用ROI计算H值不仅为骨显像的评价提供了客观的定量指标，而且提高了对鼻咽、胸骨、骶椎等处病变诊断的准确性。     

放射性碘在大鼠甲状腺内的滞留模式及剂量估算

为确定放射性碘在甲状腺内滞留模式，观察甲状腺吸收放射性碘后的生物效应，进而评价其辐射危害。方法利用活体测量方法，直接测量两个不同年龄组大鼠甲状腺内１３１Ⅰ的代谢参数。对测量数据进行处理后得到了大鼠甲状腺内１３１Ⅰ的滞留函数为三指数项函数。结果利用所得三指数项滞留函数的准确方法进行剂量估算，所得的两组动物的甲状腺平均累积吸收剂量分别为７．７Ｇｙ和１１．５Ｇｙ，而一般方法算得的大鼠甲状腺的平均累积吸收剂量比用准确方法高估了６６％～９１％。结论由于准确方法考虑到影响估算甲状腺所受剂量的一些因素，故可相对准确地反映了１３１Ⅰ所致不同年龄大鼠甲状腺的吸收剂量。     

Partial mastectomy with axillary lymph node dissection and radiotherapy as a new treatment modality of breast cancer (I).

This is the first preliminary report among two consecutive papers. Partial mastectomy(PM), axillary lymph node dissection(AD) and radiotherapy (RT) were performed on seventeen operable breast cancer patients who had been admitted from April 1991 to March 1992 to the department of surgery, Yongdong Severance Hospital for improved cosmetic appearance and better survival rate. Of seventeen patients, 47% were T1 lesion and 76% were stage I and II. Extensive intraductal component(EIC) within or around the tumor was also analyzed. Twenty nine per cent of the patients were EIC positive. The mean number of axillary lymph nodes was 21.5 after PM with AD and 20.5 after mastectomy. For radiotherapy, 4,500 rad was delivered to the breast parenchyma and 1,600 rad of boost to the primary tumor site using the electron beam method after surgery. All patients have since been living well without any local recurrence and were satisfied with breast preservation for the one-year follow-up period. We concluded that the PM, AD and RT can be another surgical treatment modality of breast cancer. A longer follow-up data will be followed on the second paper.     

Availability of elements in leaded/unleaded automobile exhausts,a leaded paint,a soil,and some mixtures

The availabilities of elements in some dust proximal sources of urban pollution were investigated. The sources were: leaded and unleaded automobile exhaust; leaded dry paint; one soil; and mixtures that included the leaded exhaust as a common component. A miniaturized modified Tessier et al. leaching scheme was developed that showed little redistribution of the most available elements. Mn, Pb, S, and Sb were the most readily available in both the leaded and unleaded exhaust; C and Pb in the paint; and Mn and S in the soil. The available elements for the leaded exhaust predominated in its mixtures with evidence of redistributions for the three-component mixture. The environmental pollution (EP) toxicity procedure with five leachings was shown to be approximately equivalent to adding the water-soluble, exchangeable, carbonate, iron/manganese oxide, and part of the organic fractions. Simulated acid rainwater leached elements up to the iron/manganese oxide fraction. The results have application to storm runoff and acid rain leaching of dusts, aerosols, wastes, and soils.