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501.
502.
基于PC Matlab平台的扩散张量参数的计算 总被引：3，自引：2，他引：1
本文介绍了在普通计算机上根据磁共振成像系统测量所得到的扩散张量数据计算扩散张量参数的方法,并且基于Matlab编程语言实现了目前应用较广的临床参数,如表观扩散系数、扩散张量的最大特征值、特征向量以及各向异型扩散系数FA等的计算. 相似文献
503.
Spaggiari M Tulla KA Aguiluz G Di Cocco P Castro Gil L Benedetti E Tzvetanov IG Giulianotti PC 《Hepatobiliary & pancreatic diseases international : HBPD INT》2022,21(4):387-391
Surgical resection remains the only definitive treatment for colorectal liver metastasis (CRLM). However, only a minority of cases are deemed resectable at the time of diagnosis. Systemic chemotherapy along with hepatic artery infusion (HAI) is an effective and safe regional chemotherapy modality for the downstaging of patients with isolated unresectable CRLM [1]. This modality improves patient response rate up to 80% and secondary resection rate up to 47% in isolated unresectable CRLM [2]. The limited usage of this therapy could be due to the morbidity and mortality associated with open surgery in a population with a reduced chance of long-term survival. The application of minimally invasive techniques circumvents the complications related to laparotomy and decreases the recovery time needed to initiate chemotherapy [3]. Although the robotic-assisted HAI pump placement has been pre- viously described [1,4], to our best knowledge, we report the first case using indocyanine green (ICG) for in vivo perfusion test. 相似文献
504.
505.
Daniel E. Ehrmann MD MS Matthew Mulvahill MS Shaunda Harendt MS CCC‐SLP BCS‐S Jessica Church CPNP‐AC/PC Amy Stimmler CPNP‐PC Piyagarnt Vichayavilas MS RD CNSC Sanja Batz OTR/L Jennifer Rodgers OTR/L Michael DiMaria MD James Jaggers MD Cindy Barrett MD MPH Jon Kaufman MD 《Congenital heart disease》2018,13(1):31-37
Background
Feeding practices after neonatal and congenital heart surgery are complicated and variable, which may be associated with prolonged hospitalization length of stay (LOS). Systematic assessment of feeding skills after cardiac surgery may earlier identify those likely to have protracted feeding difficulties, which may promote standardization of care.Methods
Neonates and infants ≤3 months old admitted for their first cardiac surgery were retrospectively identified during a 1‐year period at a single center. A systematic feeding readiness assessment (FRA) was utilized to score infant feeding skills. FRA scores were assigned immediately prior to surgery and 1, 2, and 3 weeks after surgery. FRA scores were analyzed individually and in combination as predictors of gastrostomy tube (GT) placement prior to hospital discharge by logistic regression.Results
Eighty‐six patients met inclusion criteria and 69 patients had complete data to be included in the final model. The mean age of admit was five days and 51% were male. Forty‐six percent had single ventricle physiology. Twenty‐nine (42%) underwent GT placement. The model containing both immediate presurgical and 1‐week postoperative FRA scores was of highest utility in predicting discharge with GT (intercept odds = 10.9, P = .0002; sensitivity 69%, specificity 93%, AUC 0.913). The false positive rate was 7.5%.Conclusions
In this analysis, systematic and standardized measurements of feeding readiness employed immediately before and one week after congenital cardiac surgery predicted need for GT placement prior to hospital discharge. The FRA score may be used to risk stratify patients based on likelihood of prolonged feeding difficulties, which may further improve standardization of care. 相似文献506.
Remi Stevelink Maurits WCB. Sanders Maarten P. Tuinman Eva H. Brilstra Bobby PC. Koeleman Floor E. Jansen Kees PJ. Braun 《Epileptic Disord》2018,20(2):99-115
Aims. In recent years, many different DNA mutations underlying the development of refractory epilepsy have been discovered. However, genetic diagnostics are still not routinely performed during presurgical evaluation and reports on epilepsy surgery outcome for patients with genetic refractory epilepsy are limited. We aimed to create an overview of the literature on seizure outcome following epilepsy surgery in patients with different genetic causes of refractory epilepsy. Methods. We systematically searched PubMed and Embase prior to January 2017 and included studies describing treatment outcome following epilepsy surgery in patients with genetic causes of epilepsy. We excluded studies in which patients were described with epilepsy due to Tuberous Sclerosis Complex or Sturge‐Weber syndrome (since this extensive body of research has recently been described elsewhere) and articles in which surgery was aimed to be palliative. Results. We identified 24 eligible articles, comprising a total of 82 patients who had undergone surgery for (mainly childhood‐onset) refractory epilepsy due to 15 different underlying genetic causes. The success rate of surgery varied widely across these different genetic causes. Surgery was almost never effective in patients with epilepsy due to mutations in genes involved in channel function and synaptic transmission, whereas surgery was significantly more successful regarding seizure control in patients with epilepsy due to mutations in the mTOR pathway. Patients with a lesion on MRI tended to have higher seizure freedom rates than those who were MRI‐negative. Conclusion. Although the evidence is still scarce, this systematic review suggests that studying genetic variations in patients with refractory epilepsy could help guide the selection of surgical candidates. 相似文献
507.