Multiple brain abscesses in a premature infant: complication of Staphylococcus aureus sepsis

eport a premature infant with Staphylococcus aureus sepsis, most probably originating from an infected peripheral iv site, and complicated by multiple brain abscesses. Diagnosis was made by cranial ultrasonography and computed tomography. Since systemic antibiotic treatment failed, surgical drainage was performed. The same organism that caused the initial sepsis grew from the pyogenic material obtained. The child is currently severely handicapped.     

Apparent life threatening events and infant holding practices

Two 4 week old infants are reported who suffered apparent life threatening events (ALTE) while being cradled in adult arms. The events, which could be reproduced under controlled circumstances, were not associated with any struggling by the infants. Alteration of infant holding practices in both cases resulted in cessation of the events. A case of cardiorespiratory arrest during breast feeding in an 8 week old infant that was unnoticed by her mother is also described. These cases suggest that certain infants may not respond normally to airway occlusion while being held or nursed, and show that careful study of the events surrounding ALTE may reveal contributing environmental factors. If ALTE occur around feeding time, observation of how caretakers place the infant during and after feeding may be informative.     

尼莫地平多晶型的研究

用不同有机溶剂重结晶制备了尼莫地平的两种晶型H和L,并通过红外光谱、X-射线粉末衍射、差热分析等方法得到证实。实验测定了尼莫地平两种晶型的溶解度曲线,并计算热力学数据。