Longitudinal study on forces transmitted from denture base to retainers of lower distal-extension removable partial dentures with conus crown telescopic system

The purpose of this study was to perform longitudinal measurement of forces transmitted from the denture base to retainers of lower distal-extension removable partial dentures with a conus crown telescopic system. The experimental denture was embedded with a force-detecting unit which could detect a change in lateral and vertical forces transmitted from denture base to retainers at the same time. Forces were measured during chewing of food on several separate occasions from the insertion of new dentures to about 3 months after. Max.ver (maximal mean value of vertical force) and Max.lat (maximal mean value of lateral force) were calculated from the peak level of all strokes of chewing of food at the minimum of the interocclusal distance.
The results are summarized as follows:

• (i)

  There were no significant changes of Max.ver and Max.lat;
• (ii)

  There were no significant differences of Max.ver between subjects the value of which was about 20 N;
• (iii)

  There were significant differences of Max.lat between subjects the value of which was less than 15 N.

     

Centre and magnitude of vertical forces in complete denture wearers

summary The aim of this study was to examine the centre and magnitude of a vertical component of occlusal forces in complete denture wearers during several activities using a newly developed method. A lower complete denture was divided into upper and lower parts parallel to the occlusal plane. They were connected by four force transducers which were embedded in the first premolar and the second molar portions on both sides of the denture base. Forces were recorded during tapping, chewing peanuts and raisins, and clenching. The centre and the magnitude of the forces were calculated from forces recorded by the four transducers. The maximum error of the centre was 1 mm, and the maximum error of the magnitude was 4%. The centre was observed between a first molar and the middle of the edentulous dental arch. Maximal mean value of the forces during chewing was 65-110 N.     

A Case of Adenosquamous Carcinoma of the Pancreas With a Large Cyst.

Abstract: An 81-year-old female was admitted to our hospital with right upper abdominal pain and an abdominal mass. She has suffered from diabetes mellitus for 10 years. She did not have other past history. In addition, her serum level of CA19–9 was remarkably high, 39,000U/ml. Investigations of ultrasonography, computed tomography and angiography were done. These radiological findings showed that a large cystic mass, including the pancreatic head and body, had hypervascularity. Endoscopic retrograde cholangiopancreatography (ERCP) suggested that this cystic mass originated from the main pancreatic duct and was malignant. These studies revealed that this tumor might its histological diagnosis of intraoperative biopsy revealed adenosquamous carcinoma. There have been no reports about adenosquamous cell carcinoma with a large cyst.     

THE ROLE OF MONOCYTE CHEMOATTRACTANT PROTEIN-1 (MCP-1) IN THE PATHOGENESIS OF COLLAGEN-INDUCED ARTHRITIS IN RATS

Collagen-induced arthritis was produced in rats by intradermal immunization with type II collagen and the expression and production of monocyte chemoattractant protein-1 (MCP-1) were examined by immunohistochemistry, enzyme-linked immunosorbent assay (ELISA), and Northern blot analysis. Two to three weeks after the immunization, the hindfeet showed swelling and redness, followed by the development of severe arthritis, particularly in the ankle joints. During this period, prominent infiltration of neutrophils and macrophages was observed. Sandwich ELISA and Northern blot analysis revealed that MCP-1 concentrations in the joint lavages and MCP-1 mRNA levels in the joint tissues both peaked at 2 weeks after the immunization. By immunohistochemistry, various types of cells, particularly neutrophils, macrophages, synovial cells, and vascular endothelial cells, stained positively for MCP-1. Finally, injection of a neutralizing monoclonal antibody against rat MCP-1 significantly decreased the number of exudate macrophages in the lesions and reduced the ankle swelling by about 30 per cent compared with controls. These results suggest that MCP-1 plays a critical role in this model in the recruitment of monocytes and in the development of arthritis. © 1997 John Wiley & Sons, Ltd.     

Repolarization Spatial-Time Current Abnormalities in Patients with Coronary Heart Disease

Background: Magnetocardiography (MCG) is a new technique for visualizing a current distribution in the myocardium. In recent years, current distribution parameters (CDPs) have been developed based on the distribution. The CDPs reflect spatial-time current abnormalities in patients with coronary heart disease (CHD). However, the criteria and scoring method of the abnormalities using CDPs are still controversial .
Method: We measured MCG signals for 101 normal controls and 56 CHD patients (single-, double-, and triple-vessel diseases) using a MCG system. The CDPs (maximum current vector [MCV], total current vector [TCV], current integral map, and current rotation) during ventricular repolarization were analyzed. To evaluate the CDPs that are effective in distinguishing between normal controls and CHD patients, the areas under the receiver operating characteristic curve (A_z) are calculated. Furthermore, the total scores ("0" to "4") of four CDPs with high A_z values are also calculated .
Results: MCV and TCV angles at the T-wave peak had the highest A_z value. Furthermore, TCV angular differences between the ST-T segment also had high A_z values. Using the four CDPs, the averaged total score for patients with triple-vessel disease was the highest ("2.67") compared to the other groups (normal controls: 0.53). Furthermore, based on the assumption that subjects with a total score over "1" were suspected of having CHD, sensitivity and specificity were 85.7% and 74.3%, respectively .
Conclusion: We concluded that the score and criteria using MCV and TCV during repolarization in CHD patients can reflect lesion areas and time changes of electrical activation dispersion due to ischemia .