再治疗根管粪肠球菌生物膜形成与临床表现相关性分析

目的检测粪肠球菌形成生物膜的能力,探讨其生物膜形成能力与临床表现之间的关系。方法采用96孔板法形成生物膜,结合结晶紫染色,检测临床样本中分离的53株粪肠球菌形成生物膜的能力,分析其生物膜形成能力与患牙临床表现之间的关系。结果53株粪肠球菌中,40株（75.47%）具有生物膜形成能力;在患牙的多种临床表现中,瘘道与再治疗根管粪肠球菌生物膜形成具有相关性,结果具有统计学意义（P＜0.05）。结论再治疗根管中,无瘘道的患牙分离出来的粪肠球菌生物膜形成能力强于有瘘道的患牙,临床治疗中应予以注意。     

颌间Ⅲ类矫形力对青春期恒河猴上颌骨作用的头影测量研究

目的：通过建立颌间Ⅲ类矫形动物实验模型,评价持续的颌间Ⅲ类矫形力对上颌骨的作用及动态变化规律。方法：选用青春生长发育期雌性恒河猴6只,分为实验组（3月、6月各2只）和对照组（3月、6月各1只）,实验组戴用Ⅲ类双阻板磁力矫治器,对照组不戴。实验过程中,定期拍摄X线头颅侧位片,图像输入计算机头影测量系统进行测量分析。结果：（1）与对照组相比,实验组位发生明显改变;（2）头影测量表明,对照组表现为向下向前发育,实验组矫形治疗后上颌骨相对于颅骨发生了向前的移位和少量旋转,同时其长度出现增加;（3）发现上颌骨的空间位置变化主要发生在开始矫治的两个月内,长度增加的最大值出现在第三个月左右;（4）上颌骨对矫形力作用的反应有一定的限度,增加矫形力作用时间并不能进一步促进上颌骨的更多空间变化和长度的增加。结论：Ⅲ类矫形力可以显著改变上颌骨的空间位置和固有长度,空间的位移比长度的改变出现得早。     

前牙区即刻种植短期临床研究

目的探讨前牙区即刻种植临床疗效。方法对28例因外伤、牙周病、龋病、乳牙滞留等原因拔除前牙的患者,即刻植入32颗Ankylos种植体,种植体与拔牙窝缺隙大于2 mm时,在间隙内填塞人工骨粉或于种植位点附近获取少量骨屑与人工骨粉拌合填塞缺隙,唇侧骨板有缺损或明显裂纹者应用骨引导再生技术。6个月后行烤瓷冠修复。随访3～12个月。结果随访期间32颗种植体均无松动,X线片观察种植体颈部边缘骨吸收均小于0.2 mm。结论严格掌握适应证,保证种植体良好的初期稳定性,前牙区行即刻种植能够获得良好的临床效果。     

Effect of humoral factors from hPDLSCs on the biologic activity of hABCs

Oral Diseases (2012) 18, 537–547 Objective: The human periodontal ligament stem cells (hPDLSCs) and human alveolar bone–derived stromal cells (hABCs) seem to be closely involved in the maintenance of alveolar bone in an anatomically indirect manner; however, there is little study on this matter. Therefore, the effect of hPDLSCs on the osteoclastogenic, osteogenic, and adipogenic differentiation of hABCs was evaluated, focusing on the humoral factors released by hPDLSCs. Materials and methods: Human periodontal ligament stem cells and hABCs were isolated and characterized. hPDLSCs were indirectly cocultured to observe the in vitro effect of humoral factors released from hPDLSCs on the osteoclastogenic, osteogenic, and adipogenic differentiation of hABCs. Human gingival fibroblasts (hGFs) were utilized as positive control. Results: Isolated cells demonstrated the presence of stem cells within. Indirect coculture of hPDLSCs greatly inhibited osteoclastogenesis by hABCs. Osteogenesis/adipogenesis of hABCs was also inhibited by indirect coculture with hPDLSC. The magnitude of regulatory effect from hPDLSCs was significantly greater than that of hGFs. Conclusions: Humoral factors released from hPDLSCs seemed to modulate the differentiation of hABCs, and the osteoclastogenic, osteogenic, and adipogenic differentiation of hABCs was all inhibited, suggesting the potential role of hPDLSCs in the maintenance of the alveolar bone.     

A retrospective study on 69 cases of maxillary tooth transposition

The published literature on tooth transposition includes only a few studies that have involved more than 50 subjects. The aim of the present study was to investigate the prevalence of true maxillary tooth transposition and possible associated dental anomalies in a larger sample of children. The dental records and radiographs of children who had been diagnosed as having true maxillary tooth transposition at a School Dental Clinic in Hong Kong were studied retrospectively. Data were analyzed for sex and side distribution, as well as for associated dental anomalies. Trends of differences were analyzed statistically using the Fisher exact or chi-squared test. A total of 69 cases of true maxillary tooth transposition were identified and studied; its prevalence in Hong Kong Chinese children was 0.81%. More females than males were affected, and the difference between the sexes was statistically significant (P < 0.05). The prevalence of congenitally missing teeth, microdontia of the maxillary lateral incisors or dental impaction was higher in patients with maxillary tooth transposition than in the general population (P < 0.05, P < 0.0005, and P < 0.0001, respectively). The fact that patients with maxillary tooth transposition were more likely to have congenital absence or microdontia of the maxillary lateral incisors lent further support to the contention that a developmental field defect plays a role in the pathogenesis of maxillary tooth transposition.     

选择性激光熔化技术在口腔医学中的应用

选择性激光熔化（Selective laser melting,SLM）技术是一种快速成型技术,它以其制作方便、快捷、产品组织结构密度高、精度高、避免传统加工方式原材料浪费等优点,被逐渐运用于各个行业。然而,在口腔医学中的应用还报道较少,主要集中在冠桥修复、可摘局部义齿支架、骨替代物及生物植片等方面。本文介绍了SLM技术的原理,分类以及在口腔医学中的应用特点和前景。     

乳牙滞留伴多颗多生牙及恒牙阻生1例报告

<正>多生牙也称额外牙,是一种牙齿数目的发育异常,可发生在牙弓的任何部位,其中以上颌前牙区多见。国内报道的恒牙列多生牙发生率为1%～3%[1],国外为1.04%～2.00%[2]。其中85.4%的患者只有1～2颗多生牙,3颗以上者少见[3]。本病例4颗多生牙伴乳牙滞留、恒牙阻生,导致恒牙远离牙槽骨正常位置,牙槽骨缺损失去保留价值,在临床上比较少见,总结报道如下。     

The reliability of cone-beam computed tomography (CBCT) – Generated frontal cephalograms

BackgroundThe purpose of this study was to evaluate the reliability of measurements from cone-beam computed tomography (CBCT)-generated frontal cephalogram.Materials and methodsCBCT and conventional posteroanterior (PA) cephalograms were taken from 30 adult patients. CBCT image was set according to the Frankfurt-Horizontal (FH) plane as the horizontal plane and the midsagittal reference (MSR) plane. The CBCT frontal cephalograms were generated using the orthogonal Raycast method (group CT_raycast), the orthogonal maximum intensity projection (MIP) method (group CT_MIP) after the head reorientation according to the reference planes, and the generator tool provided by the employed 3-dimensional (3D) imaging software (group CT_generator), respectively. The differences between the CBCT-generated frontal cephalograms and conventional PA cephalograms (group PA_ceph) were compared by paired t-test (p < 0.05).ResultsThe significant differences were shown in two measurements for group CT_raycast, in 12 measurements for group CT_MIP, and in eight measurements for group CT_generator. It was confirmed that the CBCT frontal cephalograms, generated by means of the Raycast method (Group CT_raycast), were more comparable to the conventional PA cephalograms in their measurements than were the others (Groups CT_MIP, CT_generator).ConclusionThis study may well suggest that frontal cephalograms derived by 3D CBCT reorientation can be effectively employed in clinical applications.     

胸段食管鳞癌术后局部区域复发患者放疗剂量研究

目的:探讨不同放疗剂量对接受放(化)疗的食管癌术后局部区域复发患者的影响。方法:收集2009—2014年间河北医科大学第四医院收疗的331例食管癌术后局部区域复发患者资料,回顾性分析其复发部位、不同放疗剂量对患者预后影响及其独立性预后影响因素等。 Kaplan- Meier法计算生存率并 ...