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71.
Monokesh Kumer Sen Shamima Nasrin Shahedur Rahman Abu Hena Mostofa Jamal 《Asian Pacific Journal of Tropical Biomedicine》2014,4(1):40-46
Objective
To study callus induction from different explants (internode, leaf, root) and in vitro plantlets propagation from medicinally important plant Achyranthes aspera L.Methods
Sterilized explants were prepared by using 0.1% HgCl2 and 0.5% Bavistin and callus was obtained when cultured onto Murashige Skoog''s (MS) medium by using different concentrations and combination of 2,4-D, NAA, BAP, IAA, IBA with 3% sucrose and 0.8% agar. Induced callus was immediately transferred to MS medium containing at different concentrations of phytohormones for shootlets and rootlets induction respectively.Results
Sterilization treatment of 0.1% HgCl2 for 2-3 min and Bavistin 0.5% for 10-12 min showed the highest percentage of asepsis and survival rate. Maximum induction of callus was obtained from a combination of 2.0 mg/L 2,4-D and 0.5 mg/L NAA from leaf. Highest shootlets number (4.83±0.17) and length (3.8±0.16) cm were observed on full strength MS medium when fortified with BAP 4.0 mg/L and KIN 0.5 mg/L. Concerted efforts of BAP 2.0 mg/L and NAA 0.5 mg/L on full strength MS medium showed highest leaf number (6.77±0.94). In vitro raised shoots were allowed to root on different strengths of MS medium fortified with IAA and IBA at different concentrations. Experimentally, 3.0 mg/L IBA was enabled to induce maximum rootlets number (10.0±9.82) on full strength MS medium. Afterwards, regenerated shoots with well developed roots were successfully subjected to hardening process and were acclimatized. The survived plantlets showed 66.67% survival frequency without any morphological abnormality.Conclusions
The results demonstrated that different explants were good source of callus induction, morphology analysis as well as indirect plantlets regeneration. 相似文献72.
Chanda Sontosh C. Haque M. Sabibul Sarwar A. K. M. Golam Nuruzzaman M. Hossain M. Amir 《Proceedings of the National Academy of Sciences, India. Section B.》2020,90(5):1153-1164
Proceedings of the National Academy of Sciences, India Section B: Biological Sciences - An investigation was carried out to evaluate the genetic variability, heritability and genetic advance in... 相似文献
73.
Amalendu Ghosh M. A. Awal Shankar Majumder Mahbub Mostofa Abul Khair M. Z. Islam D. Ramkishan Rao 《Journal of health, population, and nutrition》2012,30(4):383-393
The aim of this study was to detect arsenic concentrations in feed, well-water for drinking, eggs, and excreta of laying hens in arsenic-prone areas of Bangladesh and to assess the effect of arsenic-containing feed and well-water on the accumulation of arsenic in eggs and excreta of the same subject. One egg from each laying hen (n=248) and its excreta, feed, and well-water for drinking were collected. Total arsenic concentrations were determined by atomic absorption spectrophotometer, coupled with hydride generator. Effects of arsenic-containing feed and drinking-water on the accumulation of arsenic in eggs and excreta were analyzed by multivariate regression model, using Stata software. Mean arsenic concentrations in drinking-water, feed (dry weight [DW]), egg (wet weight [WW]), and excreta (DW) of hens were 77.3, 176.6, 19.2, and 1,439.9 ppb respectively. Significant (p<0.01) positive correlations were found between the arsenic contents in eggs and drinking-water (r=0.602), drinking-water and excreta (r=0.716), feed and excreta (r=0.402) as well as between the arsenic content in eggs and the age of the layer (r=0.243). On an average, 55% and 82% of the total variation in arsenic contents of eggs and excreta respectively could be attributed to the variation in the geographic area, age, feed type, and arsenic contents of drinking-water and feed. For each week''s increase in age of hens, arsenic content in eggs increased by 0.94%. For every 1% elevation of arsenic in drinking-water, arsenic in eggs and excreta increased by 0.41% and 0.44% respectively whereas for a 1% rise of arsenic in feed, arsenic in eggs and excreta increased by 0.40% and 0.52% respectively. These results provide evidence that, although high arsenic level prevails in well-water for drinking in Bangladesh, the arsenic shows low biological transmission capability from body to eggs and, thus, the value was below the maximum tolerable limit for humans. However, arsenic in drinking-water and/or feed makes a significant contribution to the arsenic accumulations in eggs and excreta of laying hens.Key words: Arsenic, Drinking-water, Egg, Excreta, Feed, Laying hen, Bangladesh 相似文献
74.
Diarrhoea in slum children: observation from a large diarrhoeal disease hospital in Dhaka,Bangladesh
75.
76.
77.
Multidrug resistance (MDR), the principal mechanism by which many cancers develop resistance to chemotherapy, is one of the major obstacles to the successful clinical treatment of various types of cancer. Several key regulators are responsible for mediating MDR, a process that renders chemotherapeutic drugs ineffective in the internal organelles of target cells. A nanoparticulate drug delivery system (DDS) is a potentially promising tool for circumventing such MDR, which can be achieved by targeting tumor cells themselves or tumor endothelial cells that support the survival of MDR cancer cells. The present article discusses key factors that are responsible for MDR in cancer cells, with a specific focus on the application of DDS to overcome MDR via the use of chemotherapy or macromolecules. 相似文献
78.
Yu Chen Fen Wu Faruque Parvez Alauddin Ahmed Mahbub Eunus Tyler R. McClintock Tazul Islam Patwary Tariqul Islam Anajan Kumar Ghosal Shahidul Islam Rabiul Hasan Diane Levy Golam Sarwar Vesna Slavkovich Alexander van Geen Joseph H. Graziano Habibul Ahsan 《Environmental health perspectives》2013,121(4):427-432
Background: Arsenic exposure from drinking water has been associated with heart disease; however, underlying mechanisms are uncertain.Objective: We evaluated the association between a history of arsenic exposure from drinking water and the prolongation of heart rate–corrected QT (QTc), PR, and QRS intervals.Method: We conducted a study of 1,715 participants enrolled at baseline from the Health Effects of Arsenic Longitudinal Study. We assessed the relationship of arsenic exposure in well water and urine samples at baseline with parameters of electrocardiogram (ECG) performed during 2005–2010, 5.9 years on average since baseline.Results: The adjusted odds ratio (OR) for QTc prolongation, defined as a QTc ≥ 450 msec in men and ≥ 460 msec in women, was 1.17 (95% CI: 1.01, 1.35) for a 1-SD increase in well-water arsenic (108.7 µg/L). The positive association appeared to be limited to women, with adjusted ORs of 1.24 (95% CI: 1.05, 1.47) and 1.24 (95% CI: 1.01, 1.53) for a 1-SD increase in baseline well-water and urinary arsenic, respectively, compared with 0.99 (95% CI: 0.73, 1.33) and 0.86 (95% CI: 0.49, 1.51) in men. There were no apparent associations of baseline well-water arsenic or urinary arsenic with PR or QRS prolongation in women or men.Conclusions: Long-term arsenic exposure from drinking water (average 95 µg/L; range, 0.1–790 µg/L) was associated with subsequent QT-interval prolongation in women. Future longitudinal studies with repeated ECG measurements would be valuable in assessing the influence of changes in exposure. 相似文献
79.
Lital Yinon Yu Chen Faruque Parvez Sripal Bangalore Tariqul Islam Alauddin Ahmed Muhammad Rakibuz-Zaman Rabiul Hasan Golam Sarwar Habibul Ahsan 《Preventive medicine》2013
Objective
Limited studies suggest that blood pressure variability over time is a risk factor of long-term cardiovascular outcomes. However, most of these were in populations with pre-existing cardiovascular diseases (CVD) and studies in general population are lacking.Methods
The study included 11,153 participants in a population-based, prospective cohort study in Araihazar, Bangladesh. Resting blood pressure was measured at baseline and every two years thereafter. Participants were followed up for an average of 6.5 years (2002–2009).Results
Male gender, older age, baseline systolic blood pressure (SBP), and absence of betel leaf use were independently positively associated with greater SBP variability over time. There was a significant association between SBP variability and the risk of death from overall CVD, especially from major CVD events. The positive association with the risk of death from any cause and stroke in age- and sex-adjusted models was attenuated in fully-adjusted models. In addition, the hazard ratio (HR) of stroke mortality was greater for individuals with both high baseline and high SBP variability. Similar patterns of HRs were observed for all-cause and CVD mortalities.Conclusion
In this rural Bangladeshi population, variability in SBP contributes to the risk of death from CVD and may further potentiate the increased mortality risk associated with high SBP. 相似文献80.