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Intussusception in adults is a rare cause for intestinal obstruction and is usually secondary to some lesion in the gastrointestinal tract GIT. We report a case of intestinal obstruction due to ileo-colic intussusception; an inflammatory fibroid polyp formed the leading edge of the intussusceptum, which is a rare polypoidal lesion of the GIT. 相似文献
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Although acetaminophen (APAP)-associated liver injury is well recognized, there are few reports describing APAP nephrotoxicity, and most of them are single cases. It has also been suggested that N-acetylcysteine (NAC), used to treat the hepatotoxicity, may be harmful to the kidneys. To examine this contention and to determine whether renal involvement in APAP poisoning is at all common, we analyzed the incidence and outcome of acute renal dysfunction in patients hospitalized for APAP overdose reported to our regional poison center over a year. Eleven APAP-poisoned patients had elevated liver function tests; nine of them had azotemia. Those with higher AST levels tended to be younger and to have lower APAP levels on admission. Two patients with acute renal injury died after admission. The other seven patients with renal dysfunction recovered in 2 to 7 days. Six of these received NAC; their mean serum creatinine fell from 3.2 +/- 2.0 versus 1.7 +/- 0.9 mg/dL (p < 0.05). We conclude that acute renal failure is not uncommon in APAP poisoning and appears to be unrelated to the degree of liver injury. NAC therapy did not seem to worsen nephrotoxicity. 相似文献
115.
Anshuman?DarbariEmail author Abhishek?Suryavanshi Shekhar?Tandon Girish?Chandra Prashant?Kumar?Singh 《Indian Journal of Thoracic and Cardiovascular Surgery》2005,21(4):272-276
Background Non malignant tracheo-esophageal fistula is a rare entity, which is usually post traumatic, post inflammatory or could be
a delayed presentation of congenital tracheo-esophageal fistula.
Patients and Methods In this retrospective study of seven cases, we aim to document and evaluate the causes, presentation and treatment modalities.
Results All the cases underwent surgical intervention, with single stage definitive repair in four cases and two stage repair in three
cases. There was no mortality, and minimal morbidity.
Conclusions Being a benign disease with fatal complications, early diagnosis and early surgical intervention is the key to successful
management of non-malignant tracheo-esophageal fistula. 相似文献
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Nandhini TA Thirunavukkarasu V Ravichandran MK Anuradha CV 《Journal of diabetes and its complications》2005,19(5):305-311
OBJECTIVE: The aim of the study is to investigate the effect of taurine administration on the content and characteristics of skin collagen in high-fructose-fed rats. RESEARCH DESIGN AND METHODS: Adult male Wistar rats were divided into four groups of six each: a control group (CON) and a taurine-supplemented control group (CON+TAU), a high fructose diet-fed group (FRU), and a taurine supplemented fructose diet-fed group (FRU+TAU). After 30 days, collagen was isolated from the skin, and its physicochemical properties were studied. RESULTS: Fructose administration caused an accumulation of collagen and extensive cross-linking. This was evidenced by increases in glycation, fluorescence, and peroxidation in collagen samples. The physicochemical properties of collagen, like shrinkage temperature, aldehyde content, solubility pattern, and susceptibility to denaturing agents, were altered in the fructose-fed rats. The sodium dodecyl sulphate-polyacrylamide gel electrophoretic (SDS-PAGE) pattern of collagen from fructose-fed rats showed and elevated beta component of Type I collagen. Simultaneous administration of taurine alleviated these changes. CONCLUSION: The positive influence of taurine on both collagen content and its properties suggests a potential mechanism for the ability of taurine to delay diabetic complications. 相似文献
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Pereira NL Shirali G 《Journal of the American College of Cardiology》2005,46(7):1374-5; author reply 1375-6