全文获取类型
收费全文 | 2240篇 |
免费 | 412篇 |
国内免费 | 9篇 |
专业分类
耳鼻咽喉 | 10篇 |
儿科学 | 99篇 |
妇产科学 | 176篇 |
基础医学 | 152篇 |
口腔科学 | 20篇 |
临床医学 | 1115篇 |
内科学 | 276篇 |
皮肤病学 | 19篇 |
神经病学 | 99篇 |
特种医学 | 80篇 |
外国民族医学 | 1篇 |
外科学 | 190篇 |
综合类 | 26篇 |
预防医学 | 153篇 |
眼科学 | 34篇 |
药学 | 47篇 |
肿瘤学 | 164篇 |
出版年
2024年 | 11篇 |
2023年 | 57篇 |
2021年 | 44篇 |
2020年 | 33篇 |
2019年 | 28篇 |
2018年 | 104篇 |
2017年 | 109篇 |
2016年 | 107篇 |
2015年 | 108篇 |
2014年 | 104篇 |
2013年 | 121篇 |
2012年 | 82篇 |
2011年 | 93篇 |
2010年 | 93篇 |
2009年 | 116篇 |
2008年 | 67篇 |
2007年 | 77篇 |
2006年 | 70篇 |
2005年 | 62篇 |
2004年 | 59篇 |
2003年 | 45篇 |
2002年 | 55篇 |
2001年 | 68篇 |
2000年 | 43篇 |
1999年 | 66篇 |
1998年 | 57篇 |
1997年 | 71篇 |
1996年 | 67篇 |
1995年 | 56篇 |
1994年 | 46篇 |
1993年 | 38篇 |
1992年 | 44篇 |
1991年 | 34篇 |
1990年 | 43篇 |
1989年 | 29篇 |
1988年 | 28篇 |
1987年 | 30篇 |
1986年 | 33篇 |
1985年 | 31篇 |
1984年 | 27篇 |
1983年 | 15篇 |
1982年 | 17篇 |
1981年 | 17篇 |
1980年 | 11篇 |
1979年 | 22篇 |
1978年 | 14篇 |
1977年 | 11篇 |
1976年 | 12篇 |
1975年 | 20篇 |
1974年 | 11篇 |
排序方式: 共有2661条查询结果,搜索用时 15 毫秒
91.
92.
93.
94.
The prevalence of peripheral intravenous cannulae and pattern of use: A point prevalence in a private hospital setting 下载免费PDF全文
Kelvin Wong BSc PSY MOccThy Alannah Cooper BNurs Janie Brown PhD MEd Dip App Sc Leanne Boyd PhD MN Dip App Sci Michele Levinson MD FRACP FCICM 《Journal of clinical nursing》2018,27(1-2):e363-e367
Aims and objectives
To determine the prevalence and pattern of use of peripheral intravenous cannulae in hospital wards.Background
Peripheral intravenous cannulae are commonly used in acute health care to directly access the bloodstream for the administration of medications, intravenous fluids and blood products. Peripheral intravenous cannulae are associated with multiple adverse events including hospital‐acquired bloodstream infection, thrombophlebitis and pain/discomfort. Administration of intravenous fluids is associated with impaired mobility and nocturia which may increase falls risk in the older people.Design
Observational, point prevalence study.Methods
Three private hospitals comprising a total of 1,230 beds participated in the study. Nurses recorded the presence of a peripheral intravenous cannulae, duration of insertion, state of the dressing and whether the peripheral intravenous cannulae was accessed in the previous 24 hr and for what purpose. Nurses were also asked whether they would replace the peripheral intravenous cannulae should it fail.Results
Approximately one‐quarter of patients had a peripheral intravenous cannulae, the majority of which had been present for <24 hr. The major use of the peripheral intravenous cannulae was antibiotic administration. Administration of intravenous fluids occurred in the presence of normal oral fluid intake. Nurses would not replace one‐third of peripheral intravenous cannulae in the event of failure. A majority of patients were at increased falls risk, and one‐third of these were receiving intravenous fluids.Conclusions
There is room for improvement in the utilisation of peripheral intravenous cannulae, particularly in removal and associated use of intravenous fluids. Alternative strategies for medication administration and timely switch to the oral route may reduce the risks associated with intravenous fluids.Relevance to clinical practice
Vigilance is required in the use of peripheral intravenous cannulae. Consider transition of medication administration to oral intake where possible to minimise risks associated with the use of invasive devices and increased fluid intake. 相似文献95.
S Aymé J F Pelissier J M Garnier J F Mattei F Giraud 《Journal of medical genetics》1979,16(5):393-395
We report the case of a 2-year-old girl who had signs of Duchenne type muscular dystrophy on clinical, electromyographic, laboratory, and pathological examination. The parents of the child are first cousins. A brother and nephew of the mother also had Duchenne type muscular dystrophy. Karyotype analysis in the proband showed both X chromosomes to be morphologically normal. The mother had very high plasma CK levels, equivalent to those observed in carriers of the disease. We discuss different hypothetical mechanisms designed to account for the family pedigree. 相似文献
96.
Willem Drenthen MD PhD Elke S. Hoendermis MD PhD Philip Moons RN PhD Karst Y. Heida MD Jolien W. Roos‐Hesselink MD PhD Barbara J.M. Mulder MD PhD Arie P.J. Van Dijk MD PhD Hubert W. Vliegen MD PhD Krystyna M. Sollie MD Rolf M.F. Berger MD PhD A. Titia Lely MD Mary M. Canobbio RN MN FAAN Petronella G. Pieper MD PhD 《Congenital heart disease》2008,3(4):277-283
Objectives. To investigate the age at menarche, the prevalence of menstrual cycle (interval) disorders, and determinants in women with congenital heart disease (CHD). Design. Using two CHD registries, 1802 (82%) of the 2196 women with CHD contacted (aged 18–58 years) provided written informed consent. After exclusion of patients with genetic disorders known to be associated with menstrual cycle disorders, 1593 eligible patients remained. Interviews by telephone and reviews of medical records were conducted. Results. Overall, the age at menarche was slightly increased in women with CHD (13.3 vs. 13.1 years in the general population), mainly attributable to an increased prevalence of primary amenorrhea (n = 147; 9.2%). Other menstrual cycle disorders were documented: secondary amenorrhea (n = 181, 11.4%), polymenorrhea (n = 103, 6.5%), oligomenorrhea (n = 90, 5.6%), and menorrhagia (n = 117, 6.5%). The occurrence of these disorders also depended on the presence of cyanotic heart disease, surgical status, the number of surgical interventions, and the severity of CHD. Discussion. Menstrual cycle disturbances, in particular primary amenorrhea, were frequently observed in this population. Patients with complex (cyanotic) heart disease needing repeated surgical interventions prior to menarche are especially at risk. 相似文献
97.
98.
L E Eiden R E Siegel P Giraud D E Brenneman 《Brain research. Developmental brain research》1988,44(1):141-150
The ontogeny of vasoactive intestinal polypeptide (VIP), and Met-enkephalin in primary cultures of spinal cord/dorsal root ganglia from 12-day mouse embryos was examined by radioimmunoassay and immunohistochemistry. Met-enkephalin levels rose from less than 5 to 700 pg/culture over 26 days and were half maximal by day 16-18 in culture. VIP levels rose from less than 1 to 30 pg/culture over the same period, but were already half maximal by day 9. Met-enkephalin immunoreactivity was localized in multipolar medium sized neurons while VIP immunoreactivity was visualized both in neurons with extensively branched processes and in bipolar cells some of which appeared to be dorsal root ganglion cells. Tetrodotoxin (TTX)-sensitive spontaneous release of both peptides developed in parallel with the ability to stimulate peptide release with elevated potassium. Factors affecting the ontogeny of neuropeptide expression in, and release from, spinal cord neurons can now be examined in vitro in a strictly defined neurochemical environment. 相似文献
99.
The use of psychiatry‐focused simulation in undergraduate nursing education: A systematic search and review 下载免费PDF全文
Amanda D. Vandyk RN PhD Michelle Lalonde RN MN PhD Sabrina Merali RN MN Erica Wright MLIS Irmajean Bajnok RN MScN PhD Barbara Davies RN PhD FCAHS 《International journal of mental health nursing》2018,27(2):514-535
Evidence on the use of simulation to teach psychiatry and mental health (including addiction) content is emerging, yet no summary of the implementation processes or associated outcomes exists. The aim of this study was to systematically search and review empirical literature on the use of psychiatry‐focused simulation in undergraduate nursing education. Objectives were to (i) assess the methodological quality of existing evidence on the use of simulation to teach mental health content to undergraduate nursing students, (ii) describe the operationalization of the simulations, and (iii) summarize the associated quantitative and qualitative outcomes. We conducted online database (MEDLINE, Embase, ERIC, CINAHL, PsycINFO from January 2004 to October 2015) and grey literature searches. Thirty‐two simulation studies were identified describing and evaluating six types of simulations (standardized patients, audio simulations, high‐fidelity simulators, virtual world, multimodal, and tabletop). Overall, 2724 participants were included in the studies. Studies reflected a limited number of intervention designs, and outcomes were evaluated with qualitative and quantitative methods incorporating a variety of tools. Results indicated that simulation was effective in reducing student anxiety and improving their knowledge, empathy, communication, and confidence. The summarized qualitative findings all supported the benefit of simulation; however, more research is needed to assess the comparative effectiveness of the types of simulations. Recommendations from the findings include the development of guidelines for educators to deliver each simulation component (briefing, active simulation, debriefing). Finally, consensus around appropriate training of facilitators is needed, as is consistent and agreed upon simulation terminology. 相似文献
100.