Zur Influenzafrage

Ohne ZusammenfassungMit 4 Textabbildungen.     

Über die Bedeutung von Blutveränderungen bei Spritzlackierern

Ohne Zusammenfassung     

Budd-Chiari syndrome in a patient with factor V Leiden--successful treatment by TIPSS placement followed by liver transplantation.

The causes of Budd-Chiari syndrome (BCS) comprise several diseases leading to thrombophilia. One of the most common thrombophilic disorders is resistance against activated protein C, caused by a single point mutation of the factor V gene. In December 1993, a 22-year-old patient was given a diagnosis of subacute BCS with occlusion of all major hepatic veins. Placement of a transjugular intrahepatic portosystemic stent shunt led to rapid disappearance of ascites and hepatic encephalopathy. During the following two years, recurrent partial occlusions of the shunt were treated by balloon angioplasty. The cause of the BCS still being unknown, in October 1996 we performed extensive laboratory investigations concerning states of thrombophilia and found moderately elevated IgG anticardiolipin antibodies (19.7 U/ml) and a resistance against activated protein C caused by heterozygosity for a point mutation of the factor V gene (1691G-->A; factor V Leiden). As a consequence, oral anticoagulation with coumarin was initiated. In October 1997, elective liver transplantation was performed which led to disappearance of APC resistance. Moreover, IgG anticardiolipin antibodies have been negative since then. If BCS is caused by APC resistance, liver transplantation not only treats the chronic liver disease but also cures the state of thrombophilia since factor V is mainly synthesized in the liver.     

Das Geruchsorgan von Hatteria punctata

Ohne ZusammenfassungMit 22 Textabbildungen.     

Weitere Untersuchungen Über die Chemotherapeutische Wirkung Sulfonamidhaltiger Verbindungen bei Bakteriellen Infektionen

Zusammenfassung Es wird über neue chemotherapeutisch wirksame Substanzen berichtet, die experimentell nachweisbar außer bei Streptokokkeninfektionen auch gegenüber Infektionen mit Staphylokokken, einigen anaeroben Krankheitserregern und auch gegenüber Gonokokken eine bemerkenswerte Wirkung erkennen lassen.     

Arterio-venous malformations in childhood: Clinical presentation,results after operative treatment and long-term follow-up

In a series of 182 arterio-venous malformations (AVM) recently published [8] we found 33 children aged 1 to 16 years. In 28 cases, the admitting condition was hemorrhage. For 31 AVMs total excision was possible. We observed one postoperative death accounting for a mortality of 3%. All children but two were followed-up by personal examination. Two were not able to work due to severe neurological deficits and seven had not been able to get into their intended occupation.