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排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
992.
Teriparatide vs. calcitonin in the treatment of Asian postmenopausal women with established osteoporosis 总被引:4,自引:0,他引:4
J. S. Hwang S. T. Tu T. S. Yang J. F. Chen C. J. Wang K. S. Tsai 《Osteoporosis international》2006,17(3):373-378
This study compared the clinical efficacy, safety, and tolerability of daily subcutaneous injections of teriparatide and salmon
calcitonin in the treatment of postmenopausal women with established osteoporosis in Taiwan. This 6-month, multicenter, randomized,
controlled study enrolled 63 women with established osteoporosis. They were randomized to receive either teriparatide 20 μg
or calcitonin 100 IU daily in an open-label fashion. Lumber spine, femoral neck, total hip bone mineral density (BMD), and
biochemical markers of bone turnover were measured, and adverse events and tolerability were recorded. The results at 6 months
showed that patients using teriparatide had larger mean increases in spinal BMD than those who used calcitonin (4.5% vs. 0.1%),
but the BMD changes in these two groups at the femoral neck and the total hip were not significant. There were also larger
mean increases in bone markers in the teriparatide group than in the calcitonin group (bone specific alkaline phosphatase
142% vs. 37%; osteocalcin 154% vs. 23%). We conclude that teriparatide has more positive effects on bone formation than salmon
calcitonin, as shown by the larger increments of lumbar spine BMD and bone formation markers, and caused only mild adverse
events and no significant change in liver, kidney or hematological parameters. Compared with the published global results,
teriparatide seems to be equally effective and safe to use in this Asian population. 相似文献
993.
994.
Derick T Wade 《British medical journal》2005,330(7489):468-471
995.
996.
A T Lee 《Aviation, space, and environmental medicine》1991,62(2):158-161
In-flight encounters with hazardous weather represent one of the most significant safety issues in civil aviation operations. Aircrew judgment is often cited as the probable cause of incidents and accidents involving weather, although lack of information is also a factor. The present study examines how information, presented at different times and in different forms, affects the awareness and decision-making behavior of aircrews in a flight simulation study of a recent microburst/windshear incident. In order to examine the influence of enhanced information transfer on aircrew behavior, intracrew communications and approach-to-land decisions were evaluated with conventional ATC communications and with automated cockpit alerting and display of weather information. Results of the study revealed that aircrews provided only with conventional ATC transmissions of weather information had difficulty discriminating conditions conducive to microburst events from less hazardous windshear events. Improved situation awareness for microburst events was found when ground-based convective weather information was provided in real time to aircrews. Avoidance decision-making was found to be less efficient with conventional ATC alert transmissions when compared to the performance of crews provided with a visual display of microburst events. The importance of information transfer on aircrew situation awareness and decision-making in hazardous weather avoidance is discussed. 相似文献
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