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MG Hayes M Urbanek M-F Hivert LL Armstrong J Morrison C Guo LP Lowe DA Scheftner A Pluzhnikov DM Levine CP McHugh CM Ackerman L Bouchard D Brisson BT Layden D Mirel KF Doheny MV Leya RN Lown-Hecht AR Dyer BE Metzger TE Reddy NJ Cox WL Lowe Jr. for the HAPO Study Cooperative Research Group. 《Diabetes》2013,62(10):3641
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Selective transcervical fallopian tube catheterization: technique update 总被引:15,自引:0,他引:15
A technique of transcervical fallopian tube catheterization involving use of a new vacuum hysterograph and coaxial catheter set is described. In 25 women, selective catheterization of the uterine cornua was accomplished with a 94% success rate. Ostial salpingography permitted visualization of 26% of the 46 tubes found to be obstructed or poorly visualized with conventional hysterosalpingography. Recanalization was successful in 96% of 28 proximal tubal obstructions and in 33% of six midisthmic obstructions unrelated to surgery. Recanalization attempts resulted in tubal perforations without apparent clinical effects in four tubes, one with proximal and three with midisthmic postsurgical obstructions. The new hysterograph with coaxial catheter set is more suitable for recanalization of the obstructed fallopian tubes than is the previously used balloon catheter set. 相似文献
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SUMMARY Although dissection of the thoracic aorta is a common aortic emergency, little has been written about fenestration procedures to revascularise femoral arteries that have been occluded by dissecting aneurysms arising from as high as the thoracic aorta. 相似文献
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Combined appropriate anaesthetic and surgical techniques have allowed increasing numbers of patients to be successfully managed in a general surgical recovery ward after cardiac surgery rather than in an intensive care unit. From 1983 to 1989, 933 of 1542 patients undergoing open heart surgery were transferred to the general surgical recovery ward in the immediate postoperative period. Of these, 718 (77%) had undergone coronary artery bypass grafts, sometimes combined with other procedures and 168 (18%) had had cardiac valve replacements with or without other procedures. The remaining 47 (5%) had had miscellaneous cardiac operations. Significant cardiac complications occurred in 29 (3%) patients. The 24 hour chest radiograph was reported as abnormal (mainly atelectasis and effusion) in 63% of patients. Most resolved spontaneously or with physiotherapy. Twenty nine (3%) patients were re-explored to achieve haemostasis. There were no deaths in the general surgical recovery ward. Thirty seven (4%) patients had to be transferred to the intensive care unit for various reasons. The remaining 896 patients were transferred to the general ward after one night (871 patients) or two nights (25 patients) in the general surgical recovery ward. The average duration of stay in hospital for these patients was 9·3 days. Because of the overall success of such management and the low rate of complications over 80% of patients are now managed in the general surgical recovery ward after open heart surgery. The resulting savings in capital expenditure of equipment, medical, nursing, and technical personnel are substantial, and there are major implications for the planning of new cardiothoracic units. 相似文献
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Oxidative damage is a proposed mechanism of asbestos-induced
carcinogenesis, but the detection of oxidative DNA lesions in target cells
of asbestos-induced mesothelioma has not been examined. In studies here,
DNA was isolated from both rat pleural mesothelial (RPM) cells and a human
mesothelial cell line (MET5A) after exposure in vitro to crocidolite
asbestos at various concentrations. DNA was then examined for formation of
8-hydroxydeoxyguanosine (8-OHdG) at 24, 48 and 72 h using HPLC with
electrochemical detection. In addition, steady- state mRNA levels of
manganese-containing superoxide dismutase (MnSOD) were assessed as an
indication of oxidative stress. Whereas RPM cells showed dose-dependent and
significant increases in 8-OHdG formation in response to crocidolite
asbestos or iron-chelated crocidolite fibers (but not after exposure to
glass beads), MET5A cells showed decreases in 8-OHdG. Both cell types
exhibited elevations in message levels of MnSOD. In comparison with human
MET5A cells, RPM cells exhibited increased cytotoxicity and apoptosis in
response to asbestos, as documented by cell viability assays and flow
cytometry analysis using propidium iodide. Results in RPM cells indicate
that asbestos causes oxidative damage that may result in potentially
mutagenic lesions in DNA and/or apoptosis, despite compensatory increases
in expression of an antioxidant enzyme.
相似文献
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