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991.
Genetic effects of multiple asthma loci identified by genomewide association studies on asthma and spirometric indices
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Patrice Vidal Serena Pagliarani Pasqualina Colella Helena Costa Verdera Louisa Jauze Monika Gjorgjieva Francesco Puzzo Solenne Marmier Fanny Collaud Marcelo Simon Sola Severine Charles Sabrina Lucchiari Laetitia van Wittenberghe Alban Vignaud Bernard Gjata Isabelle Richard Pascal Laforet Edoardo Malfatti Federico Mingozzi 《Molecular therapy》2018,26(3):890-901
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Gaétane Deliens Fanny Papastamou Nicolas Ruytenbeek Philippine Geelhand Mikhail Kissine 《Journal of autism and developmental disorders》2018,48(9):2938-2952
Autism Spectrum Disorder (ASD) is often described as being characterised by a uniform pragmatic impairment. However, recent evidence suggests that some areas of pragmatic functioning are preserved. This study seeks to determine to which extent context-based derivation of non-linguistically encoded meaning is functional in ASD. We compare the performance of 24 adults with ASD, and matched neuro-typical adults in two act-out pragmatic tasks. The first task examines generation of indirect request interpretations, and the second the comprehension of irony. Intact contextual comprehension of indirect requests contrasts with marked difficulties in understanding irony. These results suggest that preserved pragmatics in ASD is limited to egocentric processing of context, which does not rely on assumptions about the speaker’s mental states. 相似文献
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Dani Nadel Avinoam Danin Robert C. Power Arlene M. Rosen Fanny Bocquentin Alexander Tsatskin Danny Rosenberg Reuven Yeshurun Lior Weissbrod Noemi R. Rebollo Omry Barzilai Elisabetta Boaretto 《Proceedings of the National Academy of Sciences of the United States of America》2013,110(29):11774-11778
Flowering plants possess mechanisms that stimulate positive emotional and social responses in humans. It is difficult to establish when people started to use flowers in public and ceremonial events because of the scarcity of relevant evidence in the archaeological record. We report on uniquely preserved 13,700–11,700-y-old grave linings made of flowers, suggesting that such use began much earlier than previously thought. The only potentially older instance is the questionable use of flowers in the Shanidar IV Neanderthal grave. The earliest cemeteries (ca. 15,000–11,500 y ago) in the Levant are known from Natufian sites in northern Israel, where dozens of burials reflect a wide range of inhumation practices. The newly discovered flower linings were found in four Natufian graves at the burial site of Raqefet Cave, Mt. Carmel, Israel. Large identified plant impressions in the graves include stems of sage and other Lamiaceae (Labiatae; mint family) or Scrophulariaceae (figwort family) species; accompanied by a plethora of phytoliths, they provide the earliest direct evidence now known for such preparation and decoration of graves. Some of the plant species attest to spring burials with a strong emphasis on colorful and aromatic flowers. Cave floor chiseling to accommodate the desired grave location and depth is also evident at the site. Thus, grave preparation was a sophisticated planned process, embedded with social and spiritual meanings reflecting a complex preagricultural society undergoing profound changes at the end of the Pleistocene. 相似文献
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Benyamine Audrey Bernard-Guervilly Fanny Tummino Céline Macagno Nicolas Daniel Laurent Valleix Sophie Granel Brigitte 《Clinical rheumatology》2017,36(11):2623-2628
Clinical Rheumatology - Lysozyme amyloidosis (ALys) is a rare autosomal dominant hereditary systemic amyloidosis associated with a large spectrum of clinical manifestations. ALys phenotype mainly... 相似文献
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