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Esperanza F. Hermida-Cadahía M. Mar Calvo J. Carlos Tutor 《Clinical biochemistry》2010,43(18):1475-1477
Only two cases have been previously described about circulating endogenous antibodies interference on the immunochemical determination of digoxin. In an elderly patient with history of social cat handling was observed a moderate positive interference (about 0.8 ng/mL) on the Dimension® DGNA digoxin immunoassay (capture rabbit antibody), which was eliminated treating the serum samples with a heterophilic blocking reagent. The Architect® immunoassay was not affected. 相似文献
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Alberto Barceló Elizabeth Cafiero Melanie de Boer Alejandro Escobar Mesa Marcelina García Lopez Rosa Aurora Jiménez Agustín Lara Esqueda José Antonio Martinez Esperanza Medina Holguin Micheline Meiners Gerson Moreno Bonfil Saturnino Navarro Ramirez Enrique Pérez Flores Sylvia Robles 《Primary Care Diabetes》2010,4(3):145-153
The prevalence of diabetes in Mexico among those 20–64 years of age has increased from 7.2% in 1993 to 10.7% in 2000. National population-based surveys in Mexico demonstrated that 50% of the total population with diabetes had blood glucose levels of 200 mg/dl or higher. Thus, diabetes care has become one of the most important public health challenges in this country. The aim of the study was to improve the quality of diabetes care in primary health care centers using the chronic care model and the breakthrough series (BTS) collaborative methodology.MethodsTen public health centers in the cities of Xalapa and Veracruz were randomly selected to participate in the project. Five of the health centers were randomly assigned to receive the intervention (intervention group) and the other five followed usual care (usual care group). The intervention was evaluated by A1c test before and after the intervention in both groups of patients. Patients were followed for 18 months from November 2002 to May 2004. Results were adjusted for the clustering of patients within practices and baseline measure.ResultsThe proportion of people with good glycemic control (A1c < 7%) among those in the intervention group increased from 28% before the intervention to 39% after the intervention. The proportion of patients achieving three or more quality improvement goals increased from 16.6% to 69.7% (p < 0.001) among the intervention group while the usual care group experienced a non-significant decrease from 12.4% to 5.9% (p = 0.118). The focus on the primary care team and the participation of people with diabetes were strategic elements incorporated into the methodology, expected to ensure sustainability of continued improvement of health outcomes.ConclusionsThe intervention introduced modifications to solve problems identified by health teams in their practice and improved process and outcome measures of quality diabetes care. Most of the actions were directed at four components of the chronic care model: self-management support, decision support, delivery system design, and clinical information systems. 相似文献