带红系增强子的人β珠蛋白基因在转基因小鼠中的表达

带红系增强子的人β珠蛋白基因在转基因小鼠中的表达李政刘德培刘庆辉郭志晨章秋珩李志杰贾佩臣梁植权β４１／４２是印度次大陆、东南亚及我国南方常见的一种血红蛋白病，纯合子呈严重的β－地中海贫血。本实验旨在建立带红系，增强子５′ＨＳ２的人β４１／４２珠蛋白基...     

四种弥漫性胸膜疾病CT影像特征

本文分析了恶性胸膜间皮瘤、胸膜转移瘤、脓胸、纤维胸等四种胸膜弥漫性疾病（共６３例，其中恶性病变３９例，良性病变２４例）的ＣＴ特征。结节性增厚、壁层胸膜厚度大于１ｃｍ及纵隔胸膜受累、肺门和纵隔淋巴结受累多见于恶性病变，其特异性分别为９６％、８７％、７９％和１００％。敏感性分别为６２％、３３％、３８％和３３％。胸膜线状粘连增厚和钙化多提示良性病变，其特异性分别为９２％和１００％，敏感性均为４６％。     

Isolation of an abnormal protein C molecule from the plasma of a patient with thrombotic diathesis

Protein C has been purified from the plasma of a patient with thrombotic diathesis. Both before and after isolation, the protein showed reduced capacity to hydrolyze synthetic substrates and to anticoagulate plasma. Proteolysis with the soluble thrombin- thrombomodulin complex proceeded normally and to completion as judged by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and Western blotting. Approximately one-third of the protein is functional, indicating a heterozygous defect. Indirect studies suggest that the abnormal component can bind to protein S and phospholipids. Both forms of activated protein C can also incorporate radiolabeled diisopropylfluorophosphate.     

Interstitial hyperthermia in combination with brachytherapy

Flexible coaxial cables were modified to serve as microwave antennas operating at a frequency of 915 MHz. These antennas were inserted into nylon afterloading tubes that had been implanted in tumors using conventional interstitial implantation techniques for iridium-192 seed brachytherapy. The tumor volume was heated to 42-45 degrees C within 15 minutes and heating was continued for a total of 1 hour per treatment. Immediately following a conventional brachytherapy dose and removal of the iridium seeds the tumors were heated again in a second treatment. This interstitial technique for delivering local hyperthermia should be compatible with most brachytherapy methods. The technique has proved so far to be practical and without complications. Temperature distributions obtained in tissue phantoms and a patient are described.     

高催乳素血症的垂体CT表现

80例临床疑垂体肿瘤的高催乳素血症患者进行了直接增强鞍区冠状扫描。本文着重介绍检查方法及CT表现,并探讨高催乳素血症与垂体病变的关系,影响病灶显示的因素及临床意义。     

Quantification of angiogenesis by CT perfusion imaging in liver tumor of rabbit

BACKGROUND:Tumor angiogenesis is essential for primary and metastatic tumor growth.Computed tomography perfusion(CTP)is a new imaging method,made possible by the recent development of fast CT scanners and improved data analysis techniques,which allows measurement of the physiologic and hemodynamic properties of tissue vasculature.This study aimed to evaluate CTP in the quantification of angiogenesis and to assess the relationship between tissue perfusion parameters and microvascular density(MVD)and vascular...