全文获取类型
收费全文 | 680篇 |
免费 | 36篇 |
国内免费 | 46篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 47篇 |
妇产科学 | 20篇 |
基础医学 | 91篇 |
口腔科学 | 39篇 |
临床医学 | 93篇 |
内科学 | 168篇 |
皮肤病学 | 10篇 |
神经病学 | 19篇 |
特种医学 | 117篇 |
外科学 | 27篇 |
综合类 | 10篇 |
预防医学 | 27篇 |
眼科学 | 3篇 |
药学 | 59篇 |
1篇 | |
肿瘤学 | 28篇 |
出版年
2023年 | 5篇 |
2022年 | 6篇 |
2021年 | 5篇 |
2019年 | 6篇 |
2018年 | 11篇 |
2017年 | 9篇 |
2016年 | 11篇 |
2015年 | 16篇 |
2014年 | 21篇 |
2013年 | 27篇 |
2012年 | 9篇 |
2011年 | 15篇 |
2010年 | 19篇 |
2009年 | 20篇 |
2008年 | 8篇 |
2007年 | 39篇 |
2006年 | 18篇 |
2005年 | 11篇 |
2004年 | 5篇 |
2003年 | 6篇 |
2002年 | 12篇 |
2001年 | 5篇 |
2000年 | 10篇 |
1999年 | 12篇 |
1998年 | 45篇 |
1997年 | 52篇 |
1996年 | 54篇 |
1995年 | 45篇 |
1994年 | 31篇 |
1993年 | 31篇 |
1992年 | 3篇 |
1991年 | 11篇 |
1990年 | 9篇 |
1989年 | 17篇 |
1988年 | 25篇 |
1987年 | 19篇 |
1986年 | 14篇 |
1985年 | 15篇 |
1984年 | 8篇 |
1983年 | 8篇 |
1982年 | 10篇 |
1981年 | 9篇 |
1980年 | 11篇 |
1979年 | 3篇 |
1978年 | 4篇 |
1977年 | 8篇 |
1976年 | 5篇 |
1975年 | 6篇 |
1973年 | 4篇 |
1967年 | 3篇 |
排序方式: 共有762条查询结果,搜索用时 15 毫秒
761.
Hairy cell leukemia: a tumor of pre-plasma cells 总被引:7,自引:0,他引:7
Monoclonal antibodies defining B-, T-, and myeloid-restricted cell surface antigens were used to characterize the lineage and state of differentiation of tumor cells isolated from 22 patients with hairy cell leukemia (HCL). These tumors were shown to be of B lineage because they strongly expressed the B cell-restricted antigens B1 and B4 and lacked T cell- and monocyte-restricted antigens. Moreover, the strong expression of the plasma cell-associated PCA-1 antigen on the majority of hairy cells suggested that these tumors correspond to later stages of B cell ontogeny. Dual fluorescence experiments further confirmed that HCL splenocytes that coexpressed B1 and PCA-1 demonstrated both the morphology and tartrate-resistant acid phosphatase positivity of hairy cells. The observation that some hairy cells either spontaneously produce immunoglobulin (Ig) or could be induced to proliferate and secrete Ig provides complementary support for the view that HCL is a pre-plasma cell tumor. However, staining of hairy cells with anti-IL2R1 monoclonal antibody, which is directed to the T cell growth factor receptor and/or with the anti-Mo1 reagent, directed to C3bi complement receptor, distinguish these cells from currently identified B cells. 相似文献
762.
The relation of human erythrocyte Rh0(D) to Du sites is an important unresolved question in the field of immunohematology. To compare the immunological reactivity of Rh0(D)-positive and Du erythrocytes, the binding characteristics of two anti-Rh0(D) antisera to human Rh0(D)- positive and Du ("low-grade") erythrocytes were studied. 14C-Protein A and direct antibody-labeled techniques were used to generate binding curves and to derive double-reciprocal plots. The results show that the number of antigen sites differ by a factor of 10 to 15 between the Rh0(D)-positive and Du red cells, but that the dissociation constants between anti-Rh0(D) and the Rh0(D) and Du antigens are indistinguishable when studied by the two labeling methods and two different anti-Rh0(D) antibodies. The extent of binding to 112 different Du samples showed a normal distribution and was independent of apparent phenotype. These data suggest immunologic identity of Rh0(D) and Du ("low-grade") sites and that the difference between the antigens of Rh0(D) and Du cells is quantitative only. The data are incompatible with the "missing mosaic" and gene interaction theories of mechanism. 相似文献