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51.
52.
Elsie E. Gulick Ph.D. R.N. Marylou Yam R.N. M.A. M.Ed. Margaret M. Touw R.N. M.S. 《International journal of nursing studies》1989,26(4):301-311
This study queried 508 persons diagnosed with multiple sclerosis (MS) regarding what conditions made performing their work or tasks ‘difficult’ and ‘easier’. The subjects represented four groups: employed outside the home, homemakers, unemployed, and retired. Their written responses were content analysed. Conditions reported to impede the performance of work and tasks were related to three categories: physical restrictions, person-environment interaction, and MS-related symptoms. Conditions reported to enhance the performance of work and tasks were related to five categories: assistive devices, human support, personal attributes, health promotion behaviors, and person-environment adjustment. Study findings provide useful information for families, health service providers and employers of persons with MS in assisting them enhance their ability to perform work or tasks. 相似文献
53.
Sultan Kav Judi Johnson Cynthia Rittenberg Paz Fernadez-Ortega Tarja Suominen Pia Riis Olsen Elisabeth Patiraki Davina Porock Annette Dahler Jolanta Toliusiene Dusanka Tadic Pongpak Pittayapan Vijay Roy Qi Wang Meric Colak Hanan Saca-Hazboun David Makumi Ilana Kadmon Sarah Ben Ami Elsie Anderson Rebecca Clark-Snow 《Supportive care in cancer》2008,16(9):1075-1083
PURPOSE: The aim of this study was to explore the nursing role in education and follow-up of patients who were taking oral chemotherapy (CT) and to identify the worldwide gap in patient education about oral CT. MATERIALS AND METHODS: Multinational Association of Supportive Care in Cancer members were invited to participate in a survey on oral CT. Nurse coordinators collected data via a 16-item questionnaire. Respondents totaled 1115 oncology nurses from 15 countries. RESULTS: Findings showed that about half of subjects work in outpatient/ambulatory clinics and had given at least two or more oral CT drugs. Although 52% had some type of guidelines/protocols, 47% reported not having received any education about oral CT drugs. While 64% report being involved in patient education, 58% of subjects indicated lack of patient education materials that are specific for oral CT agents. Only 27% stated that they gave all necessary information such as when and how to take the drugs, drug safety and storage, side effects, and symptom management. Reasons for not being involved in oral CT education and follow-up included beliefs that the physician plans the oral CT and gives patients necessary instructions (34%), that nurses only see patients who receive intravenous chemotherapy (16%), that nurses have lack of knowledge about oral agents (15%), and belief that physicians are responsible for patient follow-up. The nurses suggested better education and follow-up of patients to include the written patient education materials (33%) and professional education for nurses (30%). CONCLUSIONS: Findings revealed the need for professional education for nurses to ensure comprehensive, consistent patient education and development of written materials for patients receiving oral CT treatment. 相似文献
54.
Postprandial versus preprandial dosing of biphasic insulin aspart in elderly type 2 diabetes patients 总被引:6,自引:0,他引:6
Warren ML Conway MJ Klaff LJ Rosenstock J Allen E 《Diabetes research and clinical practice》2004,66(1):23-29
Preprandial dosing (within 5 min before meal) and postprandial dosing (15-20 min after meal onset) of NovoLog Mix 70/30 (BIAsp 30, a biphasic formulation of insulin aspart, 30% soluble and 70% protamine-crystallized) were compared in elderly (> or =65 years) type 2 diabetes patients in this open-label, 12-week, crossover study. Ninety-three patients were treated with b.i.d. preprandial injections of BIAsp 30 during a 2-week run-in period and subsequently randomized to a 4-week treatment with either pre- or postprandial b.i.d. BIAsp 30, followed by crossover to the other regimen for 4 weeks. Mean plasma glucose values during a 4-h mealtest at the end of each treatment were similar for pre- and postprandial BIAsp 30 (153 +/- 58 mg/dl and 161 +/- 59 mg/dl, respectively, difference not significant). However, the mean blood glucose increment from self-measured blood glucose values was slightly but significantly greater after postprandial injection than after preprandial injection (treatment difference: 16.3mg/dl; 95% CI: [0.5, 29.3]). Fifty-six percent of patients reported a hypoglycemic episode; postprandial injection did not increase the incidence of hypoglycemia as compared to preprandial injection (113 episodes versus 125 episodes, respectively). For some elderly type 2 diabetes patients, postprandial injection of BIAsp 30 may be an acceptable alternative to standard preprandial injection. 相似文献
55.
Bauters T Claus B Willems E De Porre J Verlooy J Benoit Y Robays H 《International journal of clinical pharmacy》2012,34(5):679-681
Accurate administration of drugs is an essential part of pharmacotherapy in children. Small differences in the amount of drugs administered, might evoke different clinical effects. This is especially of concern in drugs with a narrow therapeutic index. Guided by a case that was observed in pediatrics, some practical recommendations for the administration of oral drops in children are described. 相似文献
56.
Cobianchi L Fornoni A Pileggi A Molano RD Sanabria NY Gonzalez-Quintana J Bocca N Marzorati S Zahr E Hogan AR Ricordi C Inverardi L 《Cell transplantation》2008,17(5):559-566
Riboflavin is a water-soluble vitamin that reduces the production of proinflammatory mediators and oxygen radicals. Because islet beta-cells are very sensitive to oxidative stress and to cytokines, we investigated the possible cytoprotective effects of riboflavin on insulinoma NIT-1 cells and on isolated rodent islets. NIT-1 cells and islets cultured in the presence or absence of 10 microM riboflavin were studied at baseline and after exposure to cytokines (TNF-alpha, IL-1beta, INF-gamma). Riboflavin treatment did not affect islet cell viability as assessed by flow cytometry for caspases activation. However, riboflavin prevented the cytokine-induced increase in IL-6 mRNA expression and p38 phosphorylation analyzed by real-time PCR and immunoassay, respectively. In summary, nontoxic doses of riboflavin prevent cytokines-induced p38 phosphorylation and IL-6 upregulation in islet cells. This observation, together with the safety profile of riboflavin in the clinical setting, makes it an appealing agent for islet cytoprotection in islet transplantation protocols. 相似文献
57.
Mark Mennemeier Elsie Vezey Melissa Lamar George Jewell 《Journal of the International Neuropsychological Society》2002,8(1):107-114
Most patients with neglect demonstrate a crossover effect on line bisection. Crossover refers to a pattern of performance in which long lines (>10 cm) are bisected ipsilateral to brain injury and short lines (<2 cm) are bisected contralateral to brain injury. Crossover bisections on short lines are of interest because they are not predicted by contemporary theories concerning neglect. However, we propose that the effect depends on two independent factors that normally influence bisection performance but are merely exaggerated in neglect--a tendency to overestimate the length of short lines and underestimate long lines and a tendency to orient attention preferentially in one spatial direction. We predicted that both patients with unilateral left and right hemisphere injury would demonstrate crossover on line bisection and that they would overestimate short lines and underestimate long lines upon direct visual inspection. Further, the 2 groups were predicted to demonstrate crossover in opposite directions owing to different lesion-induced biases in attentional orientation. Testing 5 patients with right hemisphere injury and 7 patients with left hemisphere injury confirmed each prediction. Additionally, errors in length estimation were exaggerated among patients with right hemisphere injury, most of whom had neglect. It is concluded that while crossover is accentuated in cases of neglect, it is not a consequence of neglect per se. As such, crossover bisections are not at odds with contemporary neglect theory. 相似文献
58.
Oken E Taveras EM Popoola FA Rich-Edwards JW Gillman MW 《American journal of preventive medicine》2007,32(4):305-311
BACKGROUND: For many women, pregnancy begets long-term weight gain. Modifiable behaviors that contribute to postpartum weight retention have not been well studied. METHODS: Prospective cohort study of 902 women enrolled in Project Viva, examining associations of postpartum television viewing, walking, and trans fat intake with weight retention equal to or greater than 5 kg at 12 months postpartum. Data were collected in 1999-2003 and analyzed in 2005-2006. RESULTS: At 6 months postpartum, women reported a mean (SD) of 1.7 (1.3) hours of television viewing, 0.7 (0.7) hours of walking, and 1.1% (0.5) of energy intake from trans fat per day. At 1 year, participants retained a mean of 0.6 kg (range: -17.3 to 25.5), and 12% retained at least 5 kg. In multivariate logistic regression models, adjusting for maternal sociodemographics, parity, prepregnancy body mass index, gestational weight gain, breastfeeding, and smoking, the odds ratio of retaining at least 5 kg was 1.24 (95% confidence interval [CI]: 1.06-1.46) per daily hour of television viewing, 0.66 (95% CI: 0.46-0.94) per daily hour of walking, and 1.33 (95% CI: 1.09-1.62) per 0.5% increment in daily energy intake from trans fat. Women who watched less than 2 hours of television, walked at least 30 minutes, and consumed trans fat below the median had an odds ratio of 0.23 (95% CI: 0.08-0.66) of retaining at least 5 kg. CONCLUSIONS: Postpartum television viewing, walking, and trans fat intake were associated with weight retention. Interventions to modify these behaviors may help reduce excess postpartum weight gain and prevent obesity among women. 相似文献
59.
This study examined the overall life satisfaction of personal care workers (PCWs) delivering dementia care in elderly day care centers in Hong Kong. A total of 142 PCWs participated in the present study. Regression analysis results showed that self-efficacy in dementia care was a robust predictor for PCWs' life satisfaction. Female gender, perceived adequacy of training, low staff to client ratio, and high emotional support from colleagues predicted a high level of self-efficacy. To promote a higher level of life satisfaction among PCWs, it is essential for organizations to enhance their sense of self-efficacy. Providing PCWs with adequate training that address areas specific to their perceived needs is of utmost importance in achieving this goal. 相似文献
60.