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21.
Sabine Elisabeth Gabor Heiko Renner Alfred Maier Freyja Maria Smolle Jüttner 《European journal of cardio-thoracic surgery》2005,28(3):502-503
A 21-year-old female with chronic membranoproliferative nephritis was admitted for suspected esophageal disruption and asthma after severe, prolonged vomiting. At the time of admission she presented with dyspnea, tachypnea, arterial hypotension and tachycardia. Physical examination showed discrete signs of ectopic air at the neck and distended cervical veins. CT-scan of the chest showed severe mediastinal emphysema with compression of the right atrium. After cervical mediastinotomy the cardiorespiratory parameters normalized immediately. Esophagoscopy showed multiple longitudinal mucosal tears between 25 and 45 cm; fluoroscopically, there was no leakage of contrast medium. Following conservative treatment the patient recovered completely and was discharged on day 8. 相似文献
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23.
Marlies Noordzij Johanna C Korevaar Elisabeth W Boeschoten Friedo W Dekker Willem J Bos Raymond T Krediet 《Nephrology, dialysis, transplantation》2006,21(9):2676-2677
Sir, With great interest we read the editorial review of Jean etal. [1] on the relationship between hyperphosphataemia and mortalityin end-stage renal disease patients. The authors summarize resultsfrom the large USRDS and DOPPS studies in which associationsof hyperphosphataemia and increased mortality risks were 相似文献
24.
Zusammenfassung. Ziel: Die psychische Belastung bei Patienten mit akutem Herzinfarkt innerhalb der ersten 48 h auf der Intensivstation des Städtischen Krankenhauses Kiel wird mit Hilfe der Symptom-Checkliste (SCL-90-R) gemessen. Patienten und Methodik: 134 hauptsächlich wegen eines akuten Herzinfarkts aufgenommene Patienten wurden zwischen August 1996 und Juli 1999 randomisiert ausgewählt. Sie füllten einen der Intensivstation angepassten Fragebogen aus, der u. a. neben Fragen zu sozioökonomischen Daten die standardisierten SCL-90-R enthält. Ergebnisse: Erhöhte Mittelwerte zeigten sich vor allem für die Skalen Somatisierung, Ängstlichkeit, Depressivität und GSI (Global Severity Index) bei solchen Patienten, die wenig soziale Unterstützung bekamen und über ein niedriges Einkommen verfügten. Schlussfolgerung: Da für Patienten mit schlechtem sozialen Netzwerk, niedrigem sozialen Status, erhöhter Angst und Depressivität eine schlechtere Prognose hinsichtlich der Mortalität und Wiedereingliederung in den Beruf beschrieben wurde, ist es im prospektiven Verlauf dieser Studie notwendig, gerade diese Patienten hinsichtlich der Entwicklung ihrer Angst zu erfassen und zu behandeln. Abstract. Objective: 134 patients with acute myocardial infarction, who were treated in an intensive care unit (ICU) of a German hospital in Kiel between 1996 and 1999 were selected for the study to examine their psychologic symptoms. Patients and Methods: The patients were asked to fill in the self-report inventory, the Symptom Checklist-90-Revised (SCL-90-R) within the first 48 h after their arrival in the ICU. Results: Patients with a low social status were found to have elevated mean values of the following scales: somatization (0.93), depression (0.66), and anxiety (0.59). The Global Severity Index (GSI) as a global measure of psychologic distress was elevated as well (0.46). Conclusion: Since patients with a limited social network and low social status, increased anxiety and depressive scores have a poor prognosis as to their mortality and their professional reintegration, it it considered necessary for the prospective setting of this study to register particularly those patients in order to treat their anxiety. 相似文献
25.
P. Apicella Eric Legallet Elisabeth Trouche 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》1997,116(3):456-466
In the primate striatum, the tonically discharging neurons respond to conditioned stimuli associated with reward. We investigated
whether these neurons respond to the reward itself and how changes in the behavioral context in which the reward is delivered
might influence their responsiveness. A total of 286 neurons in the caudate nucleus and putamen were studied in two awake
macaque monkeys while liquid reward was delivered in three behavioral situations: (1) an instrumental task, in which reward
was delivered upon execution of a visually triggered arm movement; (2) a classically conditioned task, in which reward was
delivered 1 s after a visual signal; (3) a free reward situation, in which reward was delivered at irregular time intervals
outside of any conditioning task. The monkeys′ uncertainty about the time at which reward will be delivered was assessed by
monitoring their mouth movements. A larger proportion of neurons responsive to reward was observed in the free reward situation
(86%) than in the classically conditioned (57%) and instrumental tasks (37%). Among the neurons tested in all situations (n = 78), 24% responded to reward regardless of the situation and 65% in only one or two situations. Responses selective for
one particular situation occurred exclusively in the free reward situation. When the reward was delivered immediately after
the visual signal in the classically conditioned task, most of the neurons reduced or completely lost their responses to reward,
and other neurons remained responsive. Conversely, neuronal responses invariably persisted when reward was delivered later
than 1 s after the visual signal. This is the first report that tonic striatal neurons might display responses directly to
primary rewards. The neuronal responses were strongly influenced by the behavioral context in which the animals received the
reward. An important factor appears to be the timing of reward. These neurons might therefore contribute to a general aspect
of behavioral reactivity of the subject to relevant stimuli.
Received: 16 September 1996 / Accepted: 1 April 1997 相似文献
26.
27.
Cutaneous manifestations of Lyme borreliosis 总被引:1,自引:0,他引:1
Summary The dermatological symptoms of Lyme borreliosis present with a typical clinical pattern and characteristic time of appearance. In contrast to other manifestations of Lyme borreliosis they are easily recognizable in most of the cases. In the first stage, erythema migrans arises at the tick bite site. With this symptom the diagnosis of Lyme borreliosis can be established. During all manifestations of Lyme borreliosis the history of erythema migrans is an important parameter to verify the diagnosis. In the early stage of disease a lymphocytic proliferation can appear at the tick bite site, at the ear lobe, or at the mamilla. Borrelia lymphocytoma can be diagnosed when antibodies againstBorrelia burgdorferi are positive. Years after infection, acrodermatitis chronica atrophicans arises at distal body sites causing livid swelling and gradually skin atrophy. Skin lesions can be accompanied by neuropathies, mostly of the lower legs, which in contrast to the skin lesions, do not respond well to antibiotic therapy. There is evidence that some cases of Shulman syndrome, morphea and lichen sclerosus et atrophicus might be related to a borrelia infection as indicated by cultivation ofB. burgdorferi from skin biopsies of morphea and response to antibiotic treatment in some cases. The classical dermatological symptoms of Lyme borreliosis, erythema migrans, borrelia lymphocytoma and acrodermatitis chronica atrophicans respond to oral antibiotic treatment. In acrodermatitis chronica atrophicans parenteral antibiotic therapy is sometimes necessary.
Hautmanifestationen der Lyme-Borreliose
Zusammenfassung Dermatologische Manifestationen der Lyme-Borreliose zeichnen sich durch ihr charakteristisches Erscheinungsbild und durch den typischen Zeitpunkt ihres Auftretens aus und sind im Gegensatz zu anderen Symptomen meist gut zu diagnostizieren. Die Diagnose des Erythema chronicum migrans, das an der Zeckenstichstelle entsteht, erlaubt einerseits die exakte Diagnose einer Lyme-Borreliose und stellt in Spätstadien oft einen wichtigen anamnestischen Parameter zur Verifizierung einer durchgemachten Borrelieninfektion dar. Lymphozytäre Proliferationen können einerseits an der Zeckenstichstelle, andererseits auch an abstehenden Körperpartien beobachtet werden. Ein Borrelienlymphozytom kann dann diagnostiziert werden, wenn Antikörper gegenBorrelia burgdorferi nachweisbar sind. Die Acrodermatitis chronica atrophicans entsteht nach jahrelanger Latenz an abstehenden Körperpartien und führt zur Hautatrophie. Gelegentlich sind Begleitneuropathien möglich, welche im Gegensatz zu den Hautveränderungen auf die antibiotische Therapie nicht so gut ansprechen. Es gibt Berichte, wonach einige Fälle von Shulman Syndrom, Morphea und Lichen sclerosus et atrophicus auch durch eine Infektion mitB. burgdorferi verursacht werden. Die Isolierung vonB. burgdorferi aus Morphealäsionen dürfte dazu einen direkten Hinweis geben. Die klassischen dermatologischen Symptome Erythema chronicum migrans, Borrelienlymphozytom und Acrodermatitis chronica atrophicans sprechen auf orale antibiotische Therapie an. Bei letzterer Erkrankung muß manchmal auf eine parenterale antibiotische Therapie zurückgegriffen werden.相似文献
28.
Lutz Liefeldt Martin Buhl Britta Schweickert Elisabeth Engelmann Orhan Sezer Peter Laschinski Lothar Preuschof Hans-H Neumayer 《Nephrology, dialysis, transplantation》2002,17(10):1840-1842
29.
Molecular identification of a small supernumerary marker chromosome by in situ hybridization: diagnosis of an isochromosome 18p with probe L1.84 总被引:1,自引:0,他引:1
A dysmorphic child was found by cytogenetic analysis to have an extra small marker chromosome. The marker chromosome was shown to possess a chromosome 18 centromere by in situ hybridization, and probably represents an isochromosome 18p. Centromere specific probes should be of value in identifying extra small marker chromosomes, and thereby provide better understanding of the clinical significance of these. 相似文献
30.
Riitta Ylitalo Stig Ramel Birgitta Hammarlund Elisabeth Lindgren 《Otolaryngology--head and neck surgery》2004,131(1):29-33
OBJECTIVES: To compare the prevalence of extraesophageal reflux (EER) in patients with heartburn, posterior laryngitis (PL), and in healthy controls.Study design and setting A retrospective and prospective study including a total of 101 subjects who underwent 24-hour dual-probe pH monitoring. RESULTS: 52% of the subjects with heartburn had EER. No significant differences were found between the PL and heartburn groups for any pharyngeal reflux parameters. However, supine pharyngeal reflux was significantly more prevalent in heartburn patients with GERD than in PL patients and healthy controls (P < 0.05). Significant positive correlation (P < 0.01) was found between the percentage of time pH <4 in the pharynx and in the distal esophagus. CONCLUSION: EER occurs in the majority of heartburn patients who are lacking laryngeal symptoms. Abnormal distal esophageal acid exposure makes the occurrence of EER more likely. SIGNIFICANCE: EER appears to be a continuum without clear-cut differences between the groups. 相似文献