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排序方式: 共有676条查询结果,搜索用时 4 毫秒
671.
DC Kandiloros MD PHD GA Goletsos MD PHD TP Nikolopoulos MD PhD EA Ferekidis MD PhD AS Tsomis MD PhD GK Adamopoulos MD PHD 《International journal of clinical practice》1997,51(2):69-70
SUMMARY In this study we investigated the possible relationship of laryngeal cancer and subclinical lead intoxication, using the depression of aminolevulinic acid dehydratase (ALAD) activity in blood as indicator. Twenty-six patients with laryngeal cancer and 53 normal controls met the criteria to enter the study. Blood ALAD activity values in the patients with laryngeal cancer ranged from 27.1 to 75.3 U/l with a mean of 50.79 U/l. The respective values in the control group ranged from 36.2 to 98 U/l with a mean of 59.76 U/l. There was a statistically significant difference between the two means (0.001 <p<0.01), whereas blood lead concentrations in all patients were within normal limits. These findings support the hypothesis that low level lead intoxication (subclinical blood lead levels), from cars, industries and products, may contribute to the risk of laryngeal cancer. Further investigation is needed to clarify the exact relationship between lead and cancer of the larynx. 相似文献
672.
Lalloo DG; Trevett AJ; Black J; Mapao J; Saweri A; Naraqi S; Owens D; Kamiguti AS; Hutton RA; Theakston RD; Warrell DA 《QJM : monthly journal of the Association of Physicians》1996,89(1):25-35
Thirty-two patients with enzyme-immunoassay-proven death adder (Acanthophis
sp.) bites were studied in Port Moresby, Papua New Guinea. Eighteen were
envenomed; local signs were rare and none had incoagulable blood, but all
except one had signs of neurotoxicity. Five (27.7%) envenomed patients
required intubation and ventilation. One patient developed renal failure,
previously undescribed following death adder bites. Laboratory
investigations showed mild prolongation of prothrombin and partial
thromboplastin times in some patients. In vitro studies showed that the
venom contains anticoagulant activity, but does not cause fibrinogenolysis.
In contrast to taipan envenoming, neurotoxicity did not progress after
antivenom administration, and there was reversal of neurotoxicity, evident
within 6 h, in three severely envenomed patients treated less than 12 h
after the bite. One patient treated with antivenom and anticholinesterases
had the most dramatic response to treatment; the optimum management of
bites by this species may include prompt treatment with both antivenom and
anticholinesterases in addition to effective first aid.
相似文献
673.
674.
Robert Byamugisha Thorkild Tylleskär Mike N Kagawa Saul Onyango Charles AS Karamagi James K Tumwine 《BMC health services research》2010,10(1):290
Background
The burden of mother-to-child transmission of HIV in Uganda is high. The aim of this paper is to describe the experience of the first 7 years of the prevention of mother- to- child transmission of HIV (PMTCT) programme in Mbale Regional Hospital, Eastern Uganda, with particular reference to the lessons learnt in changing from voluntary counselling and testing (VCT) to routine counselling and testing (RCT) for HIV testing in antenatal services. 相似文献675.
High prevalence of vitamin A deficiency in Crohn’s disease patients according to serum retinol levels and the relative dose-response test 总被引:3,自引:0,他引:3
Márcia Soares-Mota Tianny A Silva Luanda M Gomes Marco AS Pinto Laura MC Mendon?a Maria Lúcia F Farias Tiago Nunes Andrea Ramalho Cyrla Zaltman 《World journal of gastroenterology : WJG》2015,21(5):1614-1620
AIM:To assess the vitamin A status of patients with Crohn’s disease(CD) by evaluating serum retinol levels and the relative dose response(RDR) test(liver retinol stores).METHODS:Vitamin A nutritional status was measured by serum retinol obtained by high performance liquid chromatography and the RDR test for evaluation of the hepatic stores.Body composition was performed by densitometry by dual-energy X-ray absorptiometry.Vitamin A dietary intake was assessed from a semiquantitative food frequency questionnaire.RESULTS:This study included 38 CD patients and 33 controls.Low serum retinol concentrations were detected in 29% of CD patients vs 15% in controls(P < 0.005).The RDR test was positive in 37% of CD patients vs 12% in controls,which indicated inadequate hepatic vitamin A stores(P < 0.005).Individuals with hypovitaminosis A had lower BMI and body fat compared with those without this deficiency.There was no association between vitamin A deficiency and its dietary intake,ileal location,presence of disease activity and prior bowel resections.CONCLUSION:Patients with CD have higher prevalence of vitamin A deficiency,as assessed by two independent methods. 相似文献
676.