全文获取类型
收费全文 | 1511篇 |
免费 | 76篇 |
国内免费 | 87篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 70篇 |
妇产科学 | 10篇 |
基础医学 | 166篇 |
口腔科学 | 24篇 |
临床医学 | 236篇 |
内科学 | 427篇 |
皮肤病学 | 38篇 |
神经病学 | 36篇 |
特种医学 | 306篇 |
外科学 | 75篇 |
综合类 | 28篇 |
预防医学 | 62篇 |
眼科学 | 8篇 |
药学 | 117篇 |
肿瘤学 | 70篇 |
出版年
2023年 | 4篇 |
2022年 | 6篇 |
2021年 | 13篇 |
2020年 | 6篇 |
2019年 | 25篇 |
2018年 | 12篇 |
2017年 | 12篇 |
2016年 | 19篇 |
2015年 | 25篇 |
2014年 | 16篇 |
2013年 | 37篇 |
2012年 | 29篇 |
2011年 | 32篇 |
2010年 | 65篇 |
2009年 | 51篇 |
2008年 | 39篇 |
2007年 | 74篇 |
2006年 | 34篇 |
2005年 | 46篇 |
2004年 | 24篇 |
2003年 | 23篇 |
2002年 | 31篇 |
2001年 | 34篇 |
2000年 | 27篇 |
1999年 | 27篇 |
1998年 | 100篇 |
1997年 | 90篇 |
1996年 | 110篇 |
1995年 | 86篇 |
1994年 | 88篇 |
1993年 | 77篇 |
1992年 | 24篇 |
1991年 | 32篇 |
1990年 | 35篇 |
1989年 | 35篇 |
1988年 | 39篇 |
1987年 | 28篇 |
1986年 | 35篇 |
1985年 | 32篇 |
1984年 | 13篇 |
1983年 | 22篇 |
1982年 | 20篇 |
1981年 | 23篇 |
1980年 | 17篇 |
1979年 | 4篇 |
1978年 | 10篇 |
1977年 | 14篇 |
1976年 | 13篇 |
1975年 | 7篇 |
1974年 | 3篇 |
排序方式: 共有1674条查询结果,搜索用时 0 毫秒
101.
102.
103.
A Lacout M El Hajjam C Julie P Lacombe JP Pelage 《Journal of Medical Imaging and Radiation Oncology》2008,52(6):580-582
We report the case of a patient with a single liver metastasis of a mucinous colonic carcinoma that mimics a haemangioma in T2‐weighted sequences. Although a very high T2 signal in non‐cystic lesions is highly specific for the diagnostic of haemangioma, the use of gadolinium‐enhancement MRI is recommended. In patients with a history of neoplasia, the diagnosis of benign liver nodules should be made with caution. 相似文献
104.
The frequency of reversible and irreversible visual impairment was determined in children with severe and profound sensorineural deafness, as subnormal vision can adversely affect their educational and social development. Eighty three of 87 such children attending an audiology service were examined to assess the incidence and severity of visual impairment. Each child underwent a detailed ophthalmic assessment. The criteria for visual impairment were visual acuity < 6/9 Snellen or equivalent and/or abnormal binocular vision. Forty five had a normal ophthalmic examination (54.2%). Twenty nine had visual impairment (34.9%) and nine had ophthalmological abnormalities that did not interfere with vision (10.9%). A higher proportion of children with risk factors for visual pathology demonstrated visual impairment than those in whom there were no risk factors. None the less, 44% of visual impairment was among patients without risk factors. The results underline the need to examine all children with severe and profound sensorineural deafness soon after diagnosis and indicate that children with multiple handicaps have a greater likelihood of visual impairment (11 of 14 cases). 相似文献
105.
G Larcos SM Gruenewald JP Fletcher 《Journal of Medical Imaging and Radiation Oncology》1995,39(3):254-256
Recent observations suggest that first degree relatives of patients with an abdominal aortic aneurysm (AAA) are also at risk for the development of this disorder. The first degree relatives of 130 adults with known AAA were invited to attend for an ultrasound examination. Fifty-two eligible relatives (mean age 53 years, range 41–73) from 38 families underwent sonographic screening. Using standard ultrasound criteria no participants were identified with an asymptomatic AAA. Thus, ultrasound of families of patients with AAA has a low yield and may not be useful for screening purposes. 相似文献
106.
107.
Drenth DJ Winter JB Veeger NJ Monnink SH van Boven AJ Grandjean JG Mariani MA Boonstra PW 《The Journal of thoracic and cardiovascular surgery》2002,124(1):130-135
OBJECTIVE: We sought to compare minimally invasive coronary artery bypass grafting (surgical intervention) with percutaneous transluminal coronary angioplasty with primary stenting (stenting) in patients having an isolated high-grade stenosis (American College of Cardiology/American Heart Association classification type B2 or C) of the proximal left anterior descending coronary artery. At 6 months, both procedures were compared on the basis of quantitative angiography and clinical outcome. METHODS: Both treatments were compared in a single-center, prospective, randomized study. The primary end point of this study was quantitative angiographic outcome at 6 months. The secondary end point was 6-month clinical outcome. Statistical analysis was performed in accordance with the intention-to-treat principle. RESULTS: From March 1997 to September 1999, patients with angina pectoris caused by an isolated high-grade stenosis of the proximal left anterior descending coronary artery were randomly assigned to surgical intervention (n = 51) or stenting (n = 51). At 6 months, quantitative coronary angiography showed an anastomotic stenosis rate of 4% after surgical intervention and a restenosis rate of 29% after stenting (P <.001). Periprocedural events did not significantly differ between surgical intervention and stenting. After surgical intervention, 2 patients died; no patients died after stenting. After 6 months, no significant difference was found for major adverse cardiac or cerebral events and need for repeat target vessel revascularization. After 6 months, return of angina pectoris, physical work capacity, and use of antianginal drugs did not significantly differ between treatments. CONCLUSIONS: After 6 months, surgical intervention had a significantly better angiographic outcome than stenting in patients with an isolated high-grade stenosis of the proximal left anterior descending coronary artery. Clinical outcome did not significantly differ between treatments. 相似文献
108.
109.
110.
P Boutouyrie S Laurent B Laloux O Lidove JP Grunfeld DP Germain 《Acta paediatrica (Oslo, Norway : 1992)》2002,91(S439):62-66
Aim : The enzymatic defect in Fabry disease results in the slow systemic deposition of uncleaved glycosphingolipids in the lysosomes of vascular endothelium and smooth muscle cells, leading to ischaemic strokes, cardiomyopathy and renal failure. Whereas it is known that Fabry disease affects small blood vessels, little is known about its effects on peripheral large arteries. We therefore set out to compare parameters of arterial wall structure and function in a cohort of patients with Fabry disease and an age-matched control group. Methods : Large artery phenotype was non-invasively investigated in 21 hemizygous patients with Fabry disease and 24 age-matched male controls. Common carotid and radial artery diameter, intima-media thickness (IMT) and distensibility were determined with high-definition echotracking systems and aplanation tonometry. Results : Patients with Fabry disease had a significant twofold increase in radial artery IMT and distensibility, independent of body surface area, age and mean blood pressure. In both groups, older age at the time of examination was significantly associated with larger radial artery IMT. The relationship between age and radial IMT was 2.3-fold higher in patients with Fabry disease than in controls ( p > 0.01). Carotid IMT was mildly but significantly increased in patients with Fabry disease (+18%), whereas distensibility was unchanged.
Conclusion : This study presents evidence of a major increase in arterial wall thickness and distensibility, measurable at the site of a medium-sized artery, in a cohort of patients with classic Fabry disease. 相似文献
Conclusion : This study presents evidence of a major increase in arterial wall thickness and distensibility, measurable at the site of a medium-sized artery, in a cohort of patients with classic Fabry disease. 相似文献