全文获取类型
收费全文 | 1025篇 |
免费 | 66篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 39篇 |
妇产科学 | 21篇 |
基础医学 | 121篇 |
口腔科学 | 24篇 |
临床医学 | 85篇 |
内科学 | 180篇 |
皮肤病学 | 53篇 |
神经病学 | 53篇 |
特种医学 | 159篇 |
外科学 | 135篇 |
综合类 | 23篇 |
预防医学 | 54篇 |
眼科学 | 12篇 |
药学 | 87篇 |
中国医学 | 1篇 |
肿瘤学 | 56篇 |
出版年
2023年 | 5篇 |
2021年 | 11篇 |
2020年 | 9篇 |
2019年 | 13篇 |
2018年 | 21篇 |
2017年 | 10篇 |
2016年 | 11篇 |
2015年 | 24篇 |
2014年 | 30篇 |
2013年 | 31篇 |
2012年 | 31篇 |
2011年 | 34篇 |
2010年 | 39篇 |
2009年 | 51篇 |
2008年 | 36篇 |
2007年 | 39篇 |
2006年 | 50篇 |
2005年 | 50篇 |
2004年 | 45篇 |
2003年 | 33篇 |
2002年 | 38篇 |
2001年 | 33篇 |
2000年 | 26篇 |
1999年 | 15篇 |
1998年 | 25篇 |
1997年 | 39篇 |
1996年 | 22篇 |
1995年 | 24篇 |
1994年 | 19篇 |
1993年 | 6篇 |
1992年 | 10篇 |
1991年 | 10篇 |
1990年 | 19篇 |
1989年 | 22篇 |
1988年 | 15篇 |
1987年 | 16篇 |
1986年 | 20篇 |
1985年 | 21篇 |
1984年 | 12篇 |
1983年 | 12篇 |
1982年 | 12篇 |
1981年 | 15篇 |
1980年 | 16篇 |
1979年 | 6篇 |
1978年 | 11篇 |
1977年 | 11篇 |
1976年 | 9篇 |
1975年 | 7篇 |
1971年 | 7篇 |
1969年 | 6篇 |
排序方式: 共有1104条查询结果,搜索用时 15 毫秒
81.
82.
Background Bacterial overgrowth may cause cobalamin deficiency through competition for dietary cobalamin in the small intestine. The objective of this study was to prospectively determine the prevalence of small bowel bacterial overgrowth in patients with documented cobalamin deficiency in a tertiary referral centre.
Methods Patients identified with cobalamin deficiency underwent diagnostic investigations including: Endoscopy (with gastric antrum, gastric body and duodenal biopsies and duodenal aspirate),14 C-D-Xylose breath test, intrinsic factor antibody, anti-endomysial antibody and red cell folate level. 'Definite' small bowel bacterial overgrowth was defined as either a positive 14 C-D-Xylose breath test or > 100 000 CFU/mL of culture of duodenal aspirate. 'Suspected' small bowel bacterial overgrowth was defined as an elevated red cell folate in the absence of supplemental folate therapy.
Results Over a 2-year period, 62 patients with cobalamin deficiency were identified, of whom, 26 (42%) had 'definite' small bowel bacterial overgrowth, whilst a further nine (15%) had 'suspected' small bowel bacterial overgrowth. Nineteen (31%) had pernicious anaemia, and no cause for cobalamin deficiency could be found in eight (13%) patients. The diagnosis found in the remaining patients included coeliac disease (4), Crohn's Disease (1), gastric resection (2), vegan (2), homozygotes of the MTHFR gene (C677T) mutation (2), and one had enteropathy associated with common variable immunodeficiency (CVID). 'Definite' small bowel bacterial overgrowth was found to coexist with nine of the 19 cases of pernicious anaemia, two coeliac subjects, one CVID enteropathy and one patient with the MTHFR gene mutation.
Conclusion Small bowel bacterial overgrowth is commonly associated with cobalamin deficiency. 相似文献
Methods Patients identified with cobalamin deficiency underwent diagnostic investigations including: Endoscopy (with gastric antrum, gastric body and duodenal biopsies and duodenal aspirate),
Results Over a 2-year period, 62 patients with cobalamin deficiency were identified, of whom, 26 (42%) had 'definite' small bowel bacterial overgrowth, whilst a further nine (15%) had 'suspected' small bowel bacterial overgrowth. Nineteen (31%) had pernicious anaemia, and no cause for cobalamin deficiency could be found in eight (13%) patients. The diagnosis found in the remaining patients included coeliac disease (4), Crohn's Disease (1), gastric resection (2), vegan (2), homozygotes of the MTHFR gene (C677T) mutation (2), and one had enteropathy associated with common variable immunodeficiency (CVID). 'Definite' small bowel bacterial overgrowth was found to coexist with nine of the 19 cases of pernicious anaemia, two coeliac subjects, one CVID enteropathy and one patient with the MTHFR gene mutation.
Conclusion Small bowel bacterial overgrowth is commonly associated with cobalamin deficiency. 相似文献
83.
84.
AG Dorsten 《MedR Medizinrecht》2005,23(2):102
Abstrakt Es besteht kein Auskunftsanspruch des Patienten, der die Geltendmachung von Schadensersatzansprüchen aufgrund ärztlicher Fehlbehandlung beabsichtigt, auf Bekanntgabe der Berufshaftpflichtversicherung sowie der Versicherungsvertragsnummer gegenüber dem Arzt. Der Patient muss sich vielmehr zur Geltendmachung seiner Schadensersatzansprüche an den behandelnden Arzt selbst wenden. (Leitsätze des Bearbeiters) 相似文献
85.
Three cases are presented in which double-contrast esophagograms revealed one or more plaquelike lesions in the distal esophagus, representing pseudomembrane formation in patients with severe reflux esophagitis. Although to our knowledge this finding has not been reported previously in the radiologic literature, pseudomembranes have been documented endoscopically in patients with reflux esophagitis and biopsy-proved Barrett esophagus. Radiologists should be aware of this finding, since these pseudomembranes may be indistinguishable radiographically from plaquelike carcinomas arising in Barrett esophagus. 相似文献
86.
87.
The localization of cholecystokinin immunoreactivity in the rat ovary and uterine tube 总被引:1,自引:0,他引:1
The presence of cholecystokinin (CCK) immunoreactive nerve fibres in the rat ovary and uterine tubes was detected using the peroxidase antiperoxidase (PAP) technique. The antibody used was anti CCK 4562 which reacts with CCK-4, CCK-8, CCK-12 and CCK-33 (Larsson and Rehfeld, 1977). CCK-immunoreactive nerve fibres were found between the interstitial cells of the ovary, along blood vessels, and close to smooth muscle fibres in the ovary and tubal wall. A possible role of CCK-nerves in modulation of the sensitivity of the ovarian components to other humoral and nervous stimuli is discussed. The possible control of CCK over smooth muscle fibres in the ovary and the uterine tube and its role in ovulation is a matter of further studies. 相似文献
88.
Purpose: Magnetoencephalography (MEG)/magnetic source imaging (MSI) is a noninvasive functional neuroimaging procedure used to localize language-specific regions in the brain. The Wada test, or intracarotid amobarbital procedure (IAP), is the gold standard in determining speech/language lateralization for presurgical planning, although it is invasive and associated with morbidity. The purpose of this study is to provide further validation on the use of MSI for presurgical language lateralization by comparing results against the IAP.
Methods: The sample consisted of 35 patients with epilepsy and/or brain tumor undergoing presurgical evaluation at the Minnesota Epilepsy Group. All patients received both an IAP and MSI to determine hemispheric language dominance. For MSI, a 148-channel MEG system was used to record activation of language-specific cortex by an auditory word-recognition task.
Results: The MSI and IAP were concordant in determining language in the hemisphere to be treated in 86% of the cases with sensitivity and specificity values of 80% and 100%, respectively.
Conclusions: The results from this study are consistent with prior research findings comparing functional neuroimaging procedures to the IAP in determining language lateralization in presurgical patients. The current study provides an important replication and support for Papanicolaou et al.'s findings in 2004 using a consecutive clinical sample from a different institution. An unusually high rate of atypical IAP language cases in this sample and differences between the two procedures are believed to explain the noted discrepancies. MSI is a viable noninvasive alternative to the IAP in the presurgical determination of language lateralization. 相似文献
Methods: The sample consisted of 35 patients with epilepsy and/or brain tumor undergoing presurgical evaluation at the Minnesota Epilepsy Group. All patients received both an IAP and MSI to determine hemispheric language dominance. For MSI, a 148-channel MEG system was used to record activation of language-specific cortex by an auditory word-recognition task.
Results: The MSI and IAP were concordant in determining language in the hemisphere to be treated in 86% of the cases with sensitivity and specificity values of 80% and 100%, respectively.
Conclusions: The results from this study are consistent with prior research findings comparing functional neuroimaging procedures to the IAP in determining language lateralization in presurgical patients. The current study provides an important replication and support for Papanicolaou et al.'s findings in 2004 using a consecutive clinical sample from a different institution. An unusually high rate of atypical IAP language cases in this sample and differences between the two procedures are believed to explain the noted discrepancies. MSI is a viable noninvasive alternative to the IAP in the presurgical determination of language lateralization. 相似文献
89.
90.
AG Fürth 《MedR Medizinrecht》2001,19(12):646-647
Ohne Zusammenfassung 相似文献