Anaplastic seminoma

Fourteen patients with anaplastic seminoma were analyzed retrospectively. At the time of presentation anaplastic seminoma has similar prognosis stage for stage as the classic seminoma. However, the distinctive histologic findings and the high rates of local invasion and of elevations of serum beta-subunit human chorionic gonadotropin serve to distinguish anaplastic seminoma from the classic seminoma. These features, suggesting a possibly greater metastatic potential for anaplastic seminoma, warrant its continued identification as a distinct pathologic subtype.     

Dry cough in a CAPD patient.

Case A 50-year-old female with end-stage renal disease (ESRD) treatedby peritoneal dialysis (CAPD) complained of a dry cough. Thishad bothered her mainly at night. It had first started 2 weekspreviously. There was no report of fever. She did not smoke. Since childhood she had had reflux nephropathy and chronic pyelonephritis.She had undergone several operations including a partial nephrectomyon the left side 20 years ago and a total nephrectomy on theright side. The patient developed ESRD in 2001. She requestedtreatment by CAPD and did well. Her records indicated an 800–1200ml ultrafiltration rate/day using dialysis solutions containing2.27% glucose at daytime and 1.36% glucose over night. Therewere no problems with her compliance. Her residual     

Histologic study of the attachment of muscles to the rat mandible

The relationship of muscle to periosteum, tendon and ultimately to bone was studied in histological sections of rat mandibles aged 19 days in utero to 56 days postnatal. The following stains were employed: Van Gieson, Masson trichrome, Couciero and Friere, Gomori, orcinol-new fuchsin and Fullmer. Three modes of muscle attachment to the growing rat mandible were described according to the arrangement of collagen and reticular fibres at the interface between the bone and muscles. The morphological characteristics of the three modes persisted even in 56-day-old rats. The structure of the muscle-bone interface suggested a single mechanism of adaptation of muscles to bone during growth. With maturation, the size, number and variety of cells decreased and the size and thickness of collagen fibres increased in the muscle attachments. Each muscle was attached to the mandible by one or more types of attachment defined in this study. A schematic map of the distribution of the different attachment modes associated with muscles of the rat mandible was constructed. Distinction between these modes of attachment may be important in relating the form of a bone to its function.     

Establishment of reentry intervals for organophosphate-treated cotton fields based on human data: I. Ethyl-and methyl parathion

In each of two studies, two human volunteers entered methyl- or methyl-ethyl parathion-treated cotton fields for 30-minute periods at 0, 12, 24, 48, and 72 hours after treatment; foliage residues, and skin, clothing, inhalation, and biomedical data were obtained. The hands are probably the greatest source of absorbed pesticide chemical while the respiratory system is an insignificant source. Trousers collect the largest amounts of residue but the residue on them does not necessarily undergo absorption by the skin. There is not any evidence of plasma- or red-cell cholinesterase depression or a detectable amount ofpara-nitrophenol, following one-day, single, 30-min exposure. It is estimated that an individual can absorb up to 6.0 milligrams of parathion from cotton 24 hours after treatment with parathion and up to 3.0 milligrams 48 hours after such treatment, during an actual 5-hour work day field exposure. Skin-, and clothing contamination data are inadequate bases for evaluating hazard of possible parathion poisoning. Far more useful are measurements of serum parathion, serum-, and cell cholinesterase activities, and urinary excretion ofpara-nitrophenol in exposed individuals.Contribution to Regional Project W-45, Residues of Selected Pesticides-Their Nature, Distribution, and Persistence in Plants, Animals and the Physical Environment. University of Arizona Agricultural Experiment Station journal series, number 1983.     

Serum immunoglobulins: Methods for the determination of normal values in international units

This paper describes the proper statistical methods for the determination of the range of normal values of serum immunoglobulins in any population and for the conversion of those ranges, or any serum immunoglobulin value, from mg per ml to World Health Organization International Units. In determining the normal range, it is argued that the analysis should be based upon the logarithms of the serum immunoglobulin values and that the range of normal values about the mean should be determined by the application of tolerance limits, rather than the more familiar but incorrect confidence limits. For converting normal ranges from mg per ml to International Units, methods of parallel line bioassay (for IgG and IgA) and non-linear bioassay (for IgM and IgD) are used. For both bioassay methods, graphical techniques are described.