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在微量注射大量肝脏mRNA之后,通过电压箝方法进行功能鉴定,两栖类卵母细胞成功地表达了AVPV1a受体。但在灌流AV4-8溶液时,却不能诱导卵母细胞产生内向振荡电流反应。提示AVP4-8不能通过AVPV1a受体而介导生理学效应。 相似文献
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目的:探讨血管内皮生长因子在肺癌中的表达情况与肺癌病理生物学行为之间的关系。方法:采用免疫组化SP法检测47例肺癌组织和10正常肺组织中VEGF的表达水平。结果:肺癌组织中VEGF的表达明显高于正常肺组织(P<0.005),P53、VEGF表达与肺癌的分化程度、淋巴结转移及P—TNM分期密切相关(P<0.05),与患者的性别、年龄、肿瘤大小及组织类型无关(P>0.05)。结论:检测肺癌组织中VEGF的表达水平有助于了解肿瘤的生物学行为,并可作为判断其预后的有价值指标。 相似文献
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With the development of interventional therapy, it is necessary for evaluating cerebral vessels to instruct treatment and determine prognosis of patients with ischemic stroke; however, correlation of distribution of infarction focus and clinical symptoms with degrees of cerebrovasoular stricture is still unclear.OBJECTIVE: To evaluate the characteristics of cerebral arterial stricture of patients with ischemic stroke with transcranial Doppler (TCD) and color duplex flow imaging (CDFI) and compare the correlation between distribution of cerebral infarction focus and clinical types with magnetic resonance imaging (MRI).DESIGN: Contrast observation.SETTING: Department of Neurology, the First Hospital of Jilin University.PARTICIPANTS: A total of 159 patients with ischemic stroke were selected from the Department of Neurology, the First Hospital of Jilin University from January to December 2005, including 106 males and 53 females aged from 27 to 88 years. Bases on diagnostic criteria of cerebrovascular disease established by Rao et al, clinical manifestations of all patients were evaluated with CT or nuclear magnetic resonance. All patients provided the confirmed consent.METHODS: The accepted patients received TCD and CDFI examination at 1 week after onset of ischemic stroke. Among them, 112 patients received cerebrovascular imaging examination simultaneously. MRI was used to check cerebral infarction focus and cerebrovascular stricture > 50% was regarded as the accepted vessels. In addition, DWI-T2 TCD (Germany) was used to check middle cerebral artery, and degrees of middle cerebral artery were classified into mild, moderate and severe stricture based on blood velocity (140 cm/s,180 cm/s). Stroke was classified based on characteristics of infarction focus and clinical symptoms showed with MRI and correlation with degrees of cerebrovascular stricture was analyzed simultaneously.MAIN OUTCOME MEASURES: Correlation between the characteristics of ischemic stroke and clinical symptoms checked with TCD and CDFI.RESULTS: A total of 159 patients with ischemic stroke were involved in the final analysis; in addition, 112 oases received cerebrovascular imaging examination simultaneously. ① MRI results of 159 patients with cerebral artery occlusive disease (CAOD): There were 131 patients (82.3%) with cerebral infarction, 40 (25.2%)with transient ischemic attack and 4 (2.5%) with subclavian steal syndrome (SSS). ② Infarction types with MRI examination: There were 33 patients (20.8%) with solitary cerebral infarction and 98 (61.6%) with multiple-cerebral infarction. ③ Results of TCD, CDFI, MRI angiography, CT angiography and digital subtraction angiography (DSA): Among 112 patients, 181 lesion sites (61 .8%) were located in cranium and 112 lesion sites were located out of cranium; especially, lesion site was mostly observed in stem of middle cerebral artery (31.2%) and watershed of basilar artery (7.2%) in cranium and the beginning site of internal carotid artery (21 .4%) out of cranium. ④ Correlation of vascular stricture checking with TCD, MRI and clinical diagnosis: On one hand, MRI and clinical diagnosis demonstrated that 68 patients had a watershed infarction; meanwhile,TCD examination indicated that there were 3 patients with mild vascular stricture, 24 with moderate vascular stricture and 36 with severe vascular stricture. On the other hand, among 68 patients with non-watershed infarction, there were 27 patient with mild vascular stricture, 26 with moderate vascular stricture and 15 with severe vascular stricture. There were significant differences (x2 =26.854, P =0.001 ). Clinical diagnosis indicated that 40 patients had transient ischemic attack and TCD examination demonstrated that there were 8 patient with mild vascular stricture, 12 with moderate vascular stricture and 20 with severe vascular stricture. There were significant differences as compared with 68 patients with watershed infarction (x2 =21.258, P =0.001). ⑤Correlation of vascular stricture checking with CDFI, MRI and clinical diagnosis: On one hand, among patients who were determined as watershed infarction with MRI and clinical diagnosis, CDFI examination indicated that there were 32 patients with mild vascular stricture at neck, 25 with moderate vascular stricture and 6 with severe vascular stricture. On the other hand, among patients with non-watershed infarction, there were 48 patient with mild vascular stricture, 18 with moderate vascular stricture and 2 with severe vascular stricture.There were significant differences (x2 =6.018, P =0.019). Among patients with transient ischemic attack checking with clinical diagnosis, there were 23 patient with mild vascular stricture, 9 with moderate vascular stricture and 8 with severe vascular stricture. There were no significant differences as compared with patients with non-watershed infarction (x2 =0.597, P=0.440).CONCLUSION: ① TCD and CDFI are effective marks to determine cerebral arterial stricture and hemodynamical changes. ② Infarction and transient ischemic attack at watershed are generally clinical phenotypes of CAOD patients and infarction at watershed is correlated with degrees of cerebrovascular stricture.③ TCD, MRI and clinical analysis of stroke types are significant for instructing treatment and evaluate prognosis. 相似文献
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Abstract – Dental injuries are common following facial trauma. This article presents a rare injury: the dislocation of a third molar into the maxillary sinus after complex mandibular and maxillary tuberosity fractures. The possible mechanism and clinical treatment are discussed. 相似文献
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目的:总结2岁~12岁小儿增殖腺肥大平片表现介绍测量方法;材料与方法:25小儿增殖腺肥大患儿常规摄鼻咽部侧位片均匀吸气拍照,采用鼻咽增殖腺厚度最突出部与鼻咽腔宽度比值;结果:鼻咽顶部咽后壁软组织增厚,鼻咽气道狭窄,腺/咽比值>0.8,3例;>0.7,16例;>0.6,6例;结论:均匀吸气时摄片,观察增殖腺大小形态方法简单、准确可靠。 相似文献
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A case of β-thalassemia major with a huge mass of hernatopoictic tissuc firmly attached tothe dura mater was reported This is the first case reported in China. 相似文献
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超声对宫角妊娠的诊断及治疗意义 总被引:5,自引:0,他引:5
目的 探讨对误诊率高,危害大的罕见特殊部位宫角妊娠的诊断和治疗。方法 对我院1991-2001年收治的宫角妊娠临床资料进行回顾性分析。结果 宫角妊娠17例中误诊宫内妊娠行人流失败4例。13例行腹部手术,3例行B超监视下人流术,1例行子宫动脉栓塞术。结论 宫角妊娠临床诊断困难,误诊率高,破裂后造成迅猛的腹腔内出血,应提高对少见部位宫角妊娠的认识,减少孕妇死亡。 相似文献
20.
针药合治头痛186例临床观察 总被引:1,自引:0,他引:1
在德国采用针药配合方法治疗头痛患者186例。中药以搜风化痰、活血通络为主,针刺取穴为风池、百会、神庭、太阳、合谷、足三里、三阴交、太冲等,8~4周为1疗程。结果:按德国疗效标准判断,症状消失26例,显效87例,有效51例,无效22例,总有效率为88.17%。文中尚对疗效与病种、病程、年龄、精神、体质的关系进行了分析。 相似文献