全文获取类型
收费全文 | 1192篇 |
免费 | 55篇 |
国内免费 | 5篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 42篇 |
妇产科学 | 15篇 |
基础医学 | 100篇 |
口腔科学 | 3篇 |
临床医学 | 78篇 |
内科学 | 211篇 |
皮肤病学 | 25篇 |
神经病学 | 70篇 |
特种医学 | 97篇 |
外科学 | 244篇 |
综合类 | 125篇 |
预防医学 | 107篇 |
眼科学 | 14篇 |
药学 | 63篇 |
中国医学 | 7篇 |
肿瘤学 | 46篇 |
出版年
2022年 | 8篇 |
2021年 | 11篇 |
2020年 | 14篇 |
2019年 | 17篇 |
2018年 | 20篇 |
2017年 | 17篇 |
2016年 | 8篇 |
2015年 | 22篇 |
2014年 | 30篇 |
2013年 | 39篇 |
2012年 | 54篇 |
2011年 | 44篇 |
2010年 | 36篇 |
2009年 | 41篇 |
2008年 | 65篇 |
2007年 | 39篇 |
2006年 | 67篇 |
2005年 | 63篇 |
2004年 | 54篇 |
2003年 | 39篇 |
2002年 | 52篇 |
2001年 | 44篇 |
2000年 | 31篇 |
1999年 | 27篇 |
1998年 | 34篇 |
1997年 | 33篇 |
1996年 | 23篇 |
1995年 | 12篇 |
1994年 | 14篇 |
1993年 | 8篇 |
1992年 | 35篇 |
1991年 | 27篇 |
1990年 | 27篇 |
1989年 | 23篇 |
1988年 | 30篇 |
1987年 | 14篇 |
1986年 | 14篇 |
1985年 | 19篇 |
1984年 | 13篇 |
1983年 | 12篇 |
1982年 | 9篇 |
1981年 | 7篇 |
1980年 | 8篇 |
1978年 | 4篇 |
1977年 | 6篇 |
1975年 | 6篇 |
1974年 | 6篇 |
1972年 | 3篇 |
1971年 | 3篇 |
1970年 | 3篇 |
排序方式: 共有1252条查询结果,搜索用时 15 毫秒
81.
82.
We report the clinical records of 45 children with abnormalities regarding glycemic regulation characterized by a non-insulin deficient hyperglycemia (NIDH), known under the different names of chemical diabetes, sub-clinical diabetes and more recently MODY. These 45 children belong to 31 families with 532 relatives comprising 137 cases of NIDH which could have been studied. The symptoms of this biochemical abnormality, the pathophysiology of which is not yet clearly understood, are the following: lack of clinical manifestations, except for a variable and intermittent glycosuria; constant abnormal glucose tolerance tests, above 97 percentiles of the reference value with some variations over time; normal immunoreactive insulin levels; percentage of glycosylated hemoglobin at the upper range of normal; dominant autosomal genetic transmission and no association with HLA markers like in insulin-dependent diabetes; lack of degenerative complications of the micro-angiopathic type, at least on these cases even after more than 30 years of follow-up; finally, no tendency towards insulin-dependent diabetes. The NIDH should not be confused with the slow and progressive beginning of insulin-dependent diabetes for which prolonged delay is needed to affirm the diagnosis. The frequency of the biochemical phenomena is about 1.8% of the cases of authentic diabetes mellitus occurring before the age of 15. 相似文献
83.
目的前瞻性评价经皮射频消融术(radiofrequen-cy,RF)联合经皮暂时性球囊肝静脉或门静脉大分支阻断术治疗肝脏恶性肿瘤的可行性、有效性及并发症。材料与方法 相似文献
84.
Introduction: The Armed Forces personnel are exposed to various kinds of injuries due to the nature of their duties. Increase in motorized population without taking protective measures and rise in violence has contributed towards maxillofacial injuries. The aim of this study was to determine the incidence, aetiology and management of injuries resulting in fracture of the Zygomatic complex in Armed Forces personnel and their families. 相似文献
85.
Pulmonary arteriovenous fistulas (PAVFs) are rare vascular malformations of the lung. There is a strong association with
Rendu-Osler-Weber disease. Although most patients are asymptomatic, PAVFs can cause dyspnea from a right-to-left shunt. They
can also bleed and result in hemoptysis and hemothorax. Because of paradoxical emboli, various central nervous system complications
have been described including stroke, and brain abscess. Currently, spiral computed tomography offers the most practical method
for establishing the presence of PAVFs. Most patients should be treated. Therapeutic options include angiographic embolization
with metal coils or balloon occlusion and surgical excision. Angiographic treatment has become the mainstay of therapy for
most patients during the last decade. It is less invasive and can be repeated easily. Surgery, which usually consists of a
conservative lung resection, is associated with low morbidity and a low recurrence rate. Both therapeutic approaches are discussed.
The Mayo Clinic surgical experience of the last 20 years for PAVFs is presented. 相似文献
86.
87.
J.L. Flippen‐Anderson J.R. Deschamps C. George V.J. Hruby A. Misicka A.W. Lipkowski 《Chemical biology & drug design》2002,59(3):123-133
Abstract: Biphalin is a dimeric opioid peptide, composed of two tetrapeptides connected ‘tail‐to‐tail’, that exhibits a high affinity for all three opioid receptor types (i.e. µ, δ and κ). This study presents the X‐ray crystal structure of biphalin sulfate and compares it to other opioids that interact with the same biological targets. Both halves of the molecule have a folded backbone conformation but differ significantly from one another. Residues 1–4 in biphalin, which compare well with the δ selective opioid peptide DADLE, fold into a random coil. Residues 5–8, which can be fit to the µ selective peptide d ‐TIPP‐NH2, exhibit a fairly normal type III′β bend. Biphalin also exhibits structural similarities with two naltrexone analogs, naltrexonazine and norbinaltorphamine, that are specific to µ and κ receptor sites. 相似文献
88.
89.
90.