骨性AngleⅡ类2分类错正畸治疗前后硬组织的变化

目的:采用直丝弓矫治器矫治成年患者骨性AngleⅡ类2分类错牙合,以研究正畸治疗前后牙、颌硬组织变化,评价正畸矫治效果。方法:本文选择了8例AngleⅡ类2分类错牙合成年患者,男3例,女5例,年龄19~27岁,平均23.6岁。拔除双侧上颌第一双尖牙,运用直丝弓矫治器进行治疗,拍摄治疗前后X线头颅定位侧位片,进行治疗前后的X线头影测量研究。结果:治疗后SNA角减小,ANB角减小,U1-SN角增大,L1-MP角增大,U1-L1角减小。上颌切牙牙根及上颌基骨明显腭向移动,减小了上颌骨突度;下颌切牙牙冠明显唇向倾斜,代偿了下颌骨后缩。结论:骨性AngleⅡ类2分类错牙合患者经过上颌拔牙矫治后,面形有所改善,取得了理想的矫治效果。     

巯亚硝基血红蛋白在小鼠体内产生一氧化氮的作用

本文用Ｂａｌｂ／ｃ小鼠观察了巯亚硝基蛋白在体内产生一氧化氮的量效关系，结果发现，ＳＮＯ－Ｈｂ在体内可剂量信赖地产生ＮＯ。     

反相高效液相色谱法测定洛氟沙星的血药浓度

采用反相ＨＰＬＣ法测定洛氟沙星的血药浓度，血浆样品用二氯甲烷在ｐＨ７．０条件下提取后进样，流动相为１０ｍ ｍｏｌ／Ｌ磷酸二氢钾－１０ｍ ｍｏｌ／Ｌ溴化四丁铵－乙腈－三乙胺（４５：４４：１０：１，磷酸调节ｐＨ２．８），紫外检测器λ＝２９５ｎｍ，最低检测浓度１０μｇ／Ｌ，线性范围：０．１￣６．０ｍｇ／Ｌ，ｒ＝０．９９９９，日内ＲＳＤ为１．３８％￣３．４２％，日间ＲＳＤ为１．１１％￣２．８９％。     

多巴酚丁胺负荷超声心动图试验

对多巴酚丁胺负荷超声心动图试验诊断冠心病的理论基础、方法学及临床应用价值作一综述     

Omega-3 fatty acid treatment fails to alter alpha 1-adrenergic receptor mediated phosphoinositide turnover in streptozotocin-induced diabetic rats

1. The effect of omega-3 fatty acid supplementation on alpha 1-adrenergic receptor-mediated phosphoinositide turnover in the hearts of 6-week streptozotocin diabetic rats was studied. 2. The diabetic state was characterized by decreased body weight gain, hypoinsulinemia and hyperglycemia. Omega-3 fatty acid treatment did not have any significant effects on the above parameters. 3. Plasma triglyceride and cholesterol levels were significantly higher in diabetic rats compared with controls. 4. Omega-3 fatty acid treatment reduced the plasma triglyceride levels in the diabetic rats, whereas plasma cholesterol levels remained unaffected. 5. Norepinephrine (10 and 100 microM) stimulated inositol monophosphate (IP1) formation was significantly decreased in the diabetic rat heart compared with controls. Omega-3 fatty acid treatment had no significant effect on the norepinephrine-mediated IP1 formation in these rats. 6. Inositol bisphosphate (IP2) formation in response to 100 microM of norepinephrine was significantly lower in the diabetic rat heart; which was also not affected by omega-3 fatty acid treatment.     

大鼠头颅瞬间侧向旋转后脑干水肿的形成及其超微形态学基础

目的：探讨头颅瞬间旋转后脑干水肿的形成及超微形态学基础。     

新药甲磺酸帕珠沙星的手性拆分

目的：建立新药甲磺酸帕珠沙星手性拆分的方法。方法：运用AD手性柱法和流动相添加剂法，考察了不同条件下对分离的影响。结果：运用这两种方法，甲磺酸帕珠沙星都可以达到基线分离，相同条件下，柱温越低，拆分因子越大。结论：在分离甲磺酸帕珠沙星时，流动相添加剂法要优于手性柱法。     

毛喉萜对人肝癌细胞增殖影响的实验研究

目的　探讨毛喉萜 (Forskolin)的抗肝癌作用。方法　采用克隆形成、MTT比色法观察毛喉萜对SMMC 772 1细胞的作用 ,并利用免疫细胞化学方法检测其对rasp2 1、p5 3蛋白表达的影响。结果　毛喉萜可明显抑制SMMC 772 1细胞的增殖 ,其抑制率与剂量呈正相关 (P <0 .0 1 ) ,经毛喉萜处理后 ,rasp2 1、p5 3蛋白表达均有明显下降。结论　毛喉萜能明显抑制肝癌SMMC 772 1细胞增殖 ,其作用可能与降低rasp2 1、p5 3蛋白表达有关。     

医学影像存储的色彩模式和文件格式的比较

本文介绍了不同的影像色彩模式和影像文件常见存储格式的特点及其在应用上的优缺点，分析了影像色彩模式、文件存储的格式与影像质量、用途的关系。