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101.
Trajectories of impairment in amyotrophic lateral sclerosis: Insights from the Pooled Resource Open‐Access ALS Clinical Trials cohort 下载免费PDF全文
Nimish J. Thakore MD DM Brittany R. Lapin PhD MPH Erik P. Pioro MD PhD Pooled Resource Open‐Access ALS Clinical Trials Consortium 《Muscle & nerve》2018,57(6):937-945
Introduction: Rate of decline of the Amyotrophic Lateral Sclerosis Functional Rating Scale‐Revised (ALSFRS‐R) score is a common outcome measure and a powerful predictor of mortality in ALS. Methods: Observed rate of decline (postslope) of ALSFRS‐R, its linearity, and its relationship to decline at first visit (preslope) were examined in the Pooled Resource Open‐Access ALS Clinical Trials cohort by using longitudinal mixed effects models. Results: Mean ALSFRS‐R postslope in 3,367 patients was ?0.99 points/month. Preslope and postslope were correlated and had powerful effects on survival. ALSFRS‐R trajectories were slightly accelerated overall, but slope and direction/degree of curvature varied. Subscore decline was sequential by site of onset. Respiratory subscore decline was the least steep. Discussion: Variable curvilinearity of ALSFRS‐R trajectories confounds interpretation in clinical studies that assume linear decline. Subscore trajectories recapitulate phenotypic diversity and topographical progression of ALS. ALSFRS‐R is better used as a multidimensional measure. Muscle Nerve 57 : 937–945, 2018 相似文献
102.
Sarah Finlayson MBChB DPhil Jasper M. Morrow FRACP Pedro M. Rodriguez Cruz MD MSc Christopher D.J. Sinclair PhD Arne Fischmann PD DrMed John S. Thornton PhD Steve Knight BSc Ray Norbury PhD Mel White BSc Michal Al‐hajjar MD Nicola Carboni MD PhD Sandeep Jayawant MD FRCPCh Stephanie A. Robb MD Tarek A. Yousry DrMed Habil FRCR David Beeson PhD Jacqueline Palace DM 《Muscle & nerve》2016,54(2):211-219
103.
2016 Dietary Salt Fact Sheet and Call to Action: The World Hypertension League,International Society of Hypertension,and the International Council of Cardiovascular Prevention and Rehabilitation 下载免费PDF全文
Norm R. C. Campbell MD FRCPC Daniel T. Lackland DrPH Mark L. Niebylski PhD MBA MS Marcelo Orias MD Kimbree A. Redburn MA Peter M. Nilsson MD PhD Xin‐Hua Zhang MD PhD Louise Burrell MD MBChB MRCP FRACP Masatsugu Horiuchi MD PhD FAHA Neil R. Poulter MBBS MSc FRCP FMed Sci Dorairaj Prabhakaran MD DM MSc FRCP FNASc Agustin J. Ramirez MD PhD Alta E. Schutte PhD MSc Rhian M. Touyz MBBCh PhD FRCP FRSE Ji‐Guang Wang MD PhD Michael A. Weber MD 《Journal of clinical hypertension (Greenwich, Conn.)》2016,18(11):1082-1085
104.
Iglesias Garriz I Sastre Ibarretxe M Delgado Fernández S Garrote Coloma C Corral Fernández F Montes Montes M Rodríguez García MA 《Revista espa?ola de cardiología》2000,53(10):1329-1334
INTRODUCTION AND OBJECTIVES: Pre-infarction angina may reduce the extent of myocardial cell necrosis and improves the prognosis after myocardial infarction. The aim of this study was to analyze the total mortality six-month after acute myocardial infarction according to the presence or absence of pre-infarction angina. METHODS: One hundred seventy-five consecutive patients with acute myocardial infarction were prospectively included, 72 (41.4%) with pre-infarction angina. They were followed for 6 months. There were 16 deaths (15.5%) in the group of patients without pre-infarction angina and 7 (9.7%) in the group with pre-infarction angina (log-rank = 1.03; p = 0.311). The hazard-risk function curves showed a higher risk of death during the entire follow-up in the group without pre-infarction angina. In the multivariate logistic regression model, the presence of pre-infarction angina does not significantly reduce the risk of death (OR = 0.43; CI 95% = 0.09-2. 22; p = 0.303). We detected a significant interaction between treatment with sulfonylureas before the infarction and the presence of pre-infarction angina (p = 0.017). CONCLUSIONS: In this study no significant differences were observed in total mortality six months after acute myocardial infarction according to the presence of pre-infarction angina. However, the risk of death seemed to be higher in the group of patients without pre-infarction angina during the entire follow-up. A significant interaction was found between the treatment with sulfonylurea drugs before infarction and the presence of pre-infarction angina. 相似文献
105.
Atrial overdrive pacing during wide QRS tachycardia with RBBB morphology. What is the mechanism? 下载免费PDF全文
106.
CorVue algorithm efficacy to predict heart failure in real life: Unnecessary and potentially misleading information? 下载免费PDF全文
107.
Nursing Students' and Tutors' Satisfaction With a New Clinical Competency System Based on the Nursing Interventions Classification 下载免费PDF全文
108.
Correction to: “Iglesias JI et al. Retrospective analysis of anti-inflammatory therapies during the first wave of COVID-19 at a community hospital. World J Crit Care Med 2021 Sep 9; 10(5): 244-259. DOI: 10.5492/wjccm.v10.i5.244. PMID: 34616660; PMCID: PMC8462025.” In this article, corrections were made to Tables. 相似文献
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