全文获取类型
收费全文 | 1338399篇 |
免费 | 112519篇 |
国内免费 | 6371篇 |
专业分类
耳鼻咽喉 | 16705篇 |
儿科学 | 43005篇 |
妇产科学 | 36554篇 |
基础医学 | 183617篇 |
口腔科学 | 36273篇 |
临床医学 | 120684篇 |
内科学 | 278498篇 |
皮肤病学 | 31886篇 |
神经病学 | 110496篇 |
特种医学 | 55533篇 |
外国民族医学 | 274篇 |
外科学 | 210335篇 |
综合类 | 31529篇 |
现状与发展 | 2篇 |
一般理论 | 414篇 |
预防医学 | 106622篇 |
眼科学 | 28086篇 |
药学 | 93703篇 |
5篇 | |
中国医学 | 2227篇 |
肿瘤学 | 70841篇 |
出版年
2018年 | 13373篇 |
2017年 | 10630篇 |
2016年 | 12794篇 |
2015年 | 14296篇 |
2014年 | 19944篇 |
2013年 | 29731篇 |
2012年 | 36231篇 |
2011年 | 38880篇 |
2010年 | 24369篇 |
2009年 | 23899篇 |
2008年 | 36358篇 |
2007年 | 38771篇 |
2006年 | 39895篇 |
2005年 | 38484篇 |
2004年 | 36721篇 |
2003年 | 35818篇 |
2002年 | 33830篇 |
2001年 | 66052篇 |
2000年 | 67917篇 |
1999年 | 56587篇 |
1998年 | 16723篇 |
1997年 | 15017篇 |
1996年 | 16014篇 |
1995年 | 16232篇 |
1994年 | 15098篇 |
1993年 | 14154篇 |
1992年 | 47098篇 |
1991年 | 45748篇 |
1990年 | 43970篇 |
1989年 | 41815篇 |
1988年 | 38758篇 |
1987年 | 38083篇 |
1986年 | 35859篇 |
1985年 | 34635篇 |
1984年 | 26358篇 |
1983年 | 22108篇 |
1982年 | 13847篇 |
1981年 | 12447篇 |
1980年 | 11719篇 |
1979年 | 23544篇 |
1978年 | 17072篇 |
1977年 | 14385篇 |
1976年 | 13182篇 |
1975年 | 13722篇 |
1974年 | 16093篇 |
1973年 | 15396篇 |
1972年 | 14173篇 |
1971年 | 13036篇 |
1970年 | 11880篇 |
1969年 | 11101篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
102.
Iron Fortification of Flours in Venezuela 总被引:1,自引:0,他引:1
This paper reviews a conference about the impact of the iron fortification program in Venezuela; it was presented at the Pan American Health Organization regional technical meeting: "Iron Fortification: Where Are We in Terms of Iron Compounds," held in Washington January 10–12, 2001. Some of the data presented were published in the American Journal of Clinical Nutrition , including stimulating results about the impact of fortification of precooked corn and white wheat flours, as well as the prevalence of anemia and iron deficiency in the Venezuelan population. This article reports results from three surveys carried out in 1997, 1998, and 1999 on the same age and socioeconomic group that had been evaluated in 1990, 1992, and 1994. This article also shows the impact of iron fortification programs and the influence of other factors on the prevalence of iron deficiency and anemia during the last 7 years. 相似文献
103.
104.
Summary Experimental data suggest that multidrug resistance in cancer may be overcome by using an increased dose of anticancer agent(s) in combination with a resistance-modifying agent (RMA). We studied the pharmacokinetics and metabolism of both epirubicin (EPI) and verapamil (VPL) to explore the possible pharmacokinetic interactions between these two drugs. Ten patients with advanced breast cancer were given EPI (40 mg/m2 in a daily i.v. bolus for 3 consecutive days), and five of them also received VPL (4×120 mg/daily p.o. for 4 consecutive days). The data indicated a significant interaction between these two drugs that affected their metabolism. The areas under the concentration-time curves (AUC) obtained for epirubicin glucuronide, epirubicinol glucuronide, and both of the 7-deoxy-aglycones were higher in the EPI+VPL group as compared with the EPI group. The AUC, terminal half-life, mean residence time, volume of distribution at steady state, and plasma clearance of EPI alone as compared with EPI+VPL did not differ significantly. These results suggest either an induction of enzymes necessary for drug metabolism or an increase in the liver blood flow, resulting in an enhanced generation of metabolites with time or in an inhibition of excretion processes. Comparisons of the AUC values obtained for EPI and its metabolites after the first, second, and third injections of EPI revealed a cumulative effect for the metabolites that was more pronounced in the EPI+VPL group, being significant (P<0.05) for epirubicin glucuronide in both treatment groups and for epirubicinol glucuronide in the EPI+VPL group. Maximal concentrations of VPL and nor-VPL reached 705±473 and 308±122 ng/ml, respectively, with the steady-state concentrations being 265±42 ng/ml for VPL and 180±12 ng/ml for nor-VPL.This study was supported by the Erich und Gertrud Roggenbuck-Stiftung zur Förderung der Krebsforschung (Hamburg). The anthracycline metabolites were kindly provided by Dr. A. Suarato (Farmitalia, Milano, Italy); nor verapamil was provided by Dr. Traugott (Knoll, Ludwigshafen, Germany) 相似文献
105.
J D Picard 《Phlébologie》1988,41(3):539-541
106.
107.
108.
APACHE II score and abdominal sepsis. A prospective study 总被引:7,自引:0,他引:7
J M Bohnen R A Mustard S E Oxholm B D Schouten 《Archives of surgery (Chicago, Ill. : 1960)》1988,123(2):225-229
Therapeutic trials for intra-abdominal sepsis require pretreatment stratification; physiologic scoring has been recently proposed for this purpose. We have prospectively tested the validity of one such scoring system, namely, the Acute Physiology and Chronic Health Evaluation (APACHE II). As part of a larger database, we correlated APACHE II scores with mortality in 100 patients hospitalized for generalized peritonitis or abdominal abscess. Use of steroids was recorded because of our suspicion that steroids increase mortality but blunt the physiologic response to sepsis. Thirty-one patients died, including 12 of 19 patients receiving steroids. Stepwise discriminant analysis revealed that the APACHE II score and steroid use were each independently associated with the rate of mortality. We report a prospective validation of pretreatment APACHE II scoring in abdominal sepsis. Steroid use is an independent risk factor. 相似文献
109.
Clinical versus ultrasonographic evaluation of scrotal disorders 总被引:1,自引:0,他引:1
B Kromann-Andersen L B Hansen P N Larsen K Lawetz P Lynge D Lysen S P Nielsen K H Stockholm P Foged 《British journal of urology》1988,61(4):350-353
Clinical and ultrasonographic examinations of scrotal disorders were compared in 166 patients in order to determine their ability to distinguish between those diseases requiring surgery and those requiring clinical follow-up only. Ultrasound examinations were efficient in discriminating between normal and pathological findings. Extra-testicular lesions were readily differentiated from testicular ones. Although both clinical and ultrasonographic examinations had high sensitivity (90%) in detecting testicular cancer, the number of false positive findings was smaller after ultrasound examination. This gave a predictive value of a positive test of 53% after ultrasound examination but only 33% after clinical examination. Ultrasound examination may, therefore, reduce the number of surgical explorations in the scrotum and should be performed in patients with suspected testicular pathology based on history and palpatory findings. 相似文献
110.
Malignant tumors of the bones 总被引:2,自引:0,他引:2
D C Dahlin 《La Chirurgia degli Organi di Movimento》1988,73(3):185-186