首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   2577052篇
  免费   213114篇
  国内免费   7678篇
耳鼻咽喉   34613篇
儿科学   84930篇
妇产科学   72251篇
基础医学   360724篇
口腔科学   74630篇
临床医学   231413篇
内科学   512914篇
皮肤病学   58533篇
神经病学   211477篇
特种医学   104477篇
外国民族医学   720篇
外科学   396254篇
综合类   63544篇
现状与发展   5篇
一般理论   913篇
预防医学   205529篇
眼科学   57435篇
药学   188008篇
  8篇
中国医学   4588篇
肿瘤学   134878篇
  2018年   25116篇
  2016年   22844篇
  2015年   26065篇
  2014年   36224篇
  2013年   54849篇
  2012年   70371篇
  2011年   74910篇
  2010年   45633篇
  2009年   43992篇
  2008年   70922篇
  2007年   75227篇
  2006年   76731篇
  2005年   74421篇
  2004年   72292篇
  2003年   69766篇
  2002年   67273篇
  2001年   120210篇
  2000年   123898篇
  1999年   104367篇
  1998年   30412篇
  1997年   27480篇
  1996年   28130篇
  1995年   27849篇
  1994年   26159篇
  1993年   24584篇
  1992年   86999篇
  1991年   84762篇
  1990年   82086篇
  1989年   79000篇
  1988年   73480篇
  1987年   72368篇
  1986年   68541篇
  1985年   66272篇
  1984年   50234篇
  1983年   42815篇
  1982年   26064篇
  1981年   23424篇
  1980年   22077篇
  1979年   46906篇
  1978年   33331篇
  1977年   28196篇
  1976年   26240篇
  1975年   27662篇
  1974年   33320篇
  1973年   32024篇
  1972年   29490篇
  1971年   27578篇
  1970年   25306篇
  1969年   23780篇
  1968年   21867篇
排序方式: 共有10000条查询结果,搜索用时 46 毫秒
81.
82.
83.
84.
85.
86.
The current situation in which the humanities are disparaged affects all university disciplines, including nursing, in whose historical evolution the humanities have always been present in one form or another. Looking beyond this disrepute, this study proposes that nursing renew its attention to classical philosophy. Specifically, it invites a close reading of Xenophon's Anabasis and Plato's Meno, to get three related goals: to show how the use of ancient texts are very valuable tools for the philosophical initiation of nursing students and can help them reflect on their choice of nursing as a practical activity; to reflect on the problem of virtue and the nature of the good life; and to show how the interaction with ancient texts allows students to reflect on questions and issues of life, theirs and others, that are not open to investigation through a purely scientific method. Consequently, both Anabasis and Meno readings strengthen the intellectual relationship between philosophy and nursing, enabling the latter to delve deeper into the key questions of its own thought as a discipline.  相似文献   
87.
Obesity Surgery - Laparoscopic sleeve gastrectomy (LSG) is increasingly playing a key role in obesity management. Such operations, however, carry complications sometimes including leaks. The...  相似文献   
88.
Lasers in Medical Science - Studies reported the harmful effects of 2,4-D on body tissues, provoking changes in the anatomy and physiology of the kidneys, liver, and testicles. Thus, the objective...  相似文献   
89.
90.

Background

Resistin is an immunometabolic mediator that is elevated in several inflammatory disorders. A ligand for Toll-like receptor 4, resistin modulates the recruitment and activation of myeloid cells, notably neutrophils. Neutrophils are major drivers of cystic fibrosis (CF) lung disease, in part due to the release of human neutrophil elastase- and myeloperoxidase-rich primary granules, leading to tissue damage. Here we assessed the relationship of resistin to CF lung disease.

Methods

Resistin levels were measured in plasma and sputum from three retrospective CF cohorts spanning a wide range of disease. We also assessed the ability of neutrophils to secrete resistin upon activation in vitro. Finally, we constructed a multivariate model assessing the relationship between resistin levels and lung function.

Results

Plasma resistin levels were only marginally higher in CF than in healthy control subjects. By contrast, sputum resistin levels were very high in CF, reaching 50–100 fold higher levels than in plasma. Among CF patients, higher plasma resistin levels were associated with allergic bronchopulmonary aspergillosis, and higher sputum resistin levels were associated with CF-related diabetes. Mechanistically, in vitro release of neutrophil primary granules was concomitant with resistin secretion. Overall, sputum resistin levels were negatively correlated with CF lung function, independently of other variables (age, sex, and genotype).

Conclusions

Our data establish relationships between resistin levels in the plasma and sputum of CF patients that correlate with disease status, and identify resistin as a novel mechanistic link between neutrophilic inflammation and lung disease in CF.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号