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Genomic c-Myc quadruplex DNA selectively kills leukemia 总被引:1,自引:0,他引:1
Sedoris KC Thomas SD Clarkson CR Muench D Islam A Singh R Miller DM 《Molecular cancer therapeutics》2012,11(1):66-76
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Given that women increasingly report using drugs to lose weight, substance abuse treatment programs must include body image, weight, eating pathology, and health knowledge as core intervention targets. This study tested the efficacy of a supplemental health and body image curriculum designed for women in substance abuse treatment who report weight concerns called Healthy Steps to Freedom (HSF). Data from 124 adult women recruited from substance abuse treatment facilities in southern Nevada completed measures of drug use, body dissatisfaction, eating pathology, thin-ideal internalization, and health knowledge/behaviors before and after participation in the 12-week HSF program. Results revealed that thin-ideal internalization, body dissatisfaction, and eating disorder symptoms significantly decreased after HSF program participation, whereas health-related behaviors (e.g., increased healthy food consumption) and knowledge (e.g., understanding of basic nutrition, exercise) increased. These results suggest that the inclusion of the HSF program in substance abuse treatment improves weight-related issues in substance-abusing women. 相似文献
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Ariella A. Friedman Cortney Wolfe-Christensen Amanda Toffoli David E. Hochsztein Jack S. Elder Yegappan Lakshmanan 《Pediatric surgery international》2013,29(6):639-643
Purpose
The American Academy of Pediatrics recently recommended against routine voiding cystourethrograms (VCUGs) in children 2 to 24 months with initial febrile UTI, raising concern for delayed diagnosis and increased risk of UTI-related renal damage from vesicoureteral reflux (VUR). We assessed factors potentially associated with higher likelihood of abnormal VCUG, including UTI recurrence, which could allow for more judicious test utilization.Methods
We retrospectively reviewed all initial VCUGs performed at Children’s Hospital of Michigan between January and June, 2010. History of recurrent UTI was ascertained by evidence of two or more prior positive cultures or history of “recurrent UTI” on VCUG requisition. Outcomes assessed included rates of VUR or any urologic abnormality on VCUG.Results
Two hundred and sixty-two patients met inclusion criteria. VUR was detected in 21.3 %, urologic abnormality including VUR in 27.4 %. Degree of bladder distension, department of referring physician, study indication, positive documented urine culture, and history of recurrent UTI or UTI and other abnormality were all not associated with increased likelihood of VUR or any urologic abnormality on VCUG.Conclusion
VUR and VCUG abnormality are no more likely when performed after recurrent UTI or for UTI plus other abnormality. This reasons against postponing VCUG until after UTI recurrence, as positive findings are no more likely in this setting. 相似文献66.
Stenehjem E Rimland D Crispell EK Stafford C Gaynes R Satola SW 《Journal of clinical microbiology》2012,50(6):2079-2081
We analyzed the cycle threshold (C(T)) of PCR surveillance MRSA swabs obtained from veterans. Lower C(T) on admission was associated with a positive culture from nasal swabs at discharge. Compared to PCR, direct plating of nasal swabs performed poorly, especially for patients with an elevated C(T). The C(T) is strongly correlated with quantitative nasal cultures. Clinical and infection control applications of the C(T) have yet to be defined and warrant further evaluation. 相似文献
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Jessica M. Valenzuela Michelle Castro Fernandez Olivia Hsin Michael A. Harris Cortney Taylor Annette M. La Greca Alan M. Delamater 《Diabetes care》2010,33(1):3-8