全文获取类型
收费全文 | 3382158篇 |
免费 | 245265篇 |
国内免费 | 8785篇 |
专业分类
耳鼻咽喉 | 46921篇 |
儿科学 | 112321篇 |
妇产科学 | 95053篇 |
基础医学 | 478989篇 |
口腔科学 | 94559篇 |
临床医学 | 304968篇 |
内科学 | 661526篇 |
皮肤病学 | 79224篇 |
神经病学 | 274373篇 |
特种医学 | 131140篇 |
外国民族医学 | 1047篇 |
外科学 | 510913篇 |
综合类 | 69604篇 |
现状与发展 | 6篇 |
一般理论 | 1206篇 |
预防医学 | 258934篇 |
眼科学 | 77024篇 |
药学 | 249804篇 |
10篇 | |
中国医学 | 6801篇 |
肿瘤学 | 181785篇 |
出版年
2018年 | 36241篇 |
2017年 | 27708篇 |
2016年 | 32043篇 |
2015年 | 36213篇 |
2014年 | 49875篇 |
2013年 | 75288篇 |
2012年 | 100337篇 |
2011年 | 106542篇 |
2010年 | 64173篇 |
2009年 | 61349篇 |
2008年 | 100236篇 |
2007年 | 106916篇 |
2006年 | 108845篇 |
2005年 | 104779篇 |
2004年 | 100988篇 |
2003年 | 97685篇 |
2002年 | 94804篇 |
2001年 | 158181篇 |
2000年 | 162109篇 |
1999年 | 137095篇 |
1998年 | 39837篇 |
1997年 | 35320篇 |
1996年 | 35564篇 |
1995年 | 34234篇 |
1994年 | 31672篇 |
1993年 | 29714篇 |
1992年 | 108132篇 |
1991年 | 104801篇 |
1990年 | 102010篇 |
1989年 | 98867篇 |
1988年 | 91063篇 |
1987年 | 89411篇 |
1986年 | 84362篇 |
1985年 | 80613篇 |
1984年 | 59901篇 |
1983年 | 51456篇 |
1982年 | 30638篇 |
1981年 | 27226篇 |
1979年 | 54318篇 |
1978年 | 38328篇 |
1977年 | 32867篇 |
1976年 | 30613篇 |
1975年 | 33033篇 |
1974年 | 38904篇 |
1973年 | 37132篇 |
1972年 | 35213篇 |
1971年 | 32617篇 |
1970年 | 30423篇 |
1969年 | 29210篇 |
1968年 | 27082篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
81.
Loss‐of‐function mutations in the gene encoding filaggrin underlie a Japanese family with food‐dependent exercise‐induced anaphylaxis 下载免费PDF全文
82.
83.
84.
Monique G. Kumar M.Phil. M.D. Heather Ciliberto M.D. Susan J. Bayliss M.D. 《Pediatric dermatology》2015,32(2):198-200
Pediatric trachyonychia is an acquired nail disease that can cause distress to families. It is a poorly understood disease, and long‐term follow‐up data are lacking. We present an institutional review of 11 children with isolated pediatric trachyonychia followed over time. Children with the diagnosis of pediatric trachyonychia were identified and invited to participate. Pictures were taken on follow‐up and a questionnaire was answered. Exclusion criteria include having another diagnosis at the initial visit that causes nail dystrophy. Eleven patients with the diagnosis of pediatric trachyonychia were available for follow‐up. The mean age of appearance was 2.7 years (range 2–7 yrs) and the average follow‐up was 66 months (range 10–126 mos). Nine patients were treated with potent topical corticosteroids, one used only petrolatum, and one took vitamin supplements. One patient was found to have an additional skin and hair diagnosis of alopecia areata on follow‐up. On follow‐up, 82% noted improvement of the nails, whereas 18% noted no change. A majority of cases of pediatric trachyonychia are isolated and improve with time, regardless of treatment. 相似文献
85.
Wojciech Szychta M.D. Ph.D. Gheorghe Cerin M.D. Ph.D. F.E.S.C. Bogdan Adrian Popa M.D. Armienti Felice M.D. Guido Lanzillo M.D. Ph.D. Marco Diena M.D. Grzegorz Opolski M.D. Ph.D. F.E.S.C. 《Echocardiography (Mount Kisco, N.Y.)》2015,32(6):1040-1043
Sinus venosus atrial septal defect (SV‐ASD) usually coexists with partial anomalous pulmonary vein connection (PAPVC). It is a difficult diagnosis in transthoracic echocardiography (TTE) due to eccentric position of defects. We present a rare case of atypical anatomical variation in PAPVC, which was never described before. Two right pulmonary veins drained into superior vena cava, which overrode SV‐ASD and interatrial septum, a third pulmonary vein into the right atrium. Complete diagnosis could not be set after TTE, nor transesophageal echocardiography, whereas angio‐CT was finally conclusive. This diagnostic approach allowed the surgical planning. 相似文献
86.
87.
88.
89.
90.
Distribution of temperature changes and neurovascular coupling in rat brain following 3,4‐methylenedioxymethamphetamine (MDMA, “ecstasy”) exposure 下载免费PDF全文
Daniel Coman Basavaraju G. Sanganahalli Lihong Jiang Fahmeed Hyder Kevin L. Behar 《NMR in biomedicine》2015,28(10):1257-1266
(+/?)3,4‐methylenedioxymethamphetamine (MDMA, “ecstasy”) is an abused psychostimulant that produces strong monoaminergic stimulation and whole‐body hyperthermia. MDMA‐induced thermogenesis involves activation of uncoupling proteins (UCPs), primarily a type specific to skeletal muscle (UCP‐3) and absent from the brain, although other UCP types are expressed in the brain (e.g. thalamus) and might contribute to thermogenesis. Since neuroimaging of brain temperature could provide insights into MDMA action, we measured spatial distributions of systemically administered MDMA‐induced temperature changes and dynamics in rat cortex and subcortex using a novel magnetic resonance method, Biosensor Imaging of Redundant Deviation in Shifts (BIRDS), with an exogenous temperature‐sensitive probe (thulium ion and macrocyclic chelate 1,4,7,10‐tetraazacyclododecane‐1,4,7,10‐tetramethyl‐1,4,7,10‐tetraacetate (DOTMA4?)). The MDMA‐induced temperature rise was greater in the cortex than in the subcortex (1.6 ± 0.4 °C versus 1.3 ± 0.4 °C) and occurred more rapidly (2.0 ± 0.2 °C/h versus 1.5 ± 0.2 °C/h). MDMA‐induced temperature changes and dynamics in the cortex and body were correlated, although the body temperature exceeded the cortex temperature before and after MDMA. Temperature, neuronal activity, and blood flow (CBF) were measured simultaneously in the cortex and subcortex (i.e. thalamus) to investigate possible differences of MDMA‐induced warming across brain regions. MDMA‐induced warming correlated with increases in neuronal activity and blood flow in the cortex, suggesting that the normal neurovascular response to increased neural activity was maintained. In contrast to the cortex, a biphasic relationship was seen in the subcortex (i.e. thalamus), with a decline in CBF as temperature and neural activity rose, transitioning to a rise in CBF for temperature above 37 °C, suggesting that MDMA affected CBF and neurovascular coupling differently in subcortical regions. Considering that MDMA effects on CBF and heat dissipation (as well as potential heat generation) may vary regionally, neuroprotection may require different cooling strategies. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献