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Ruth Ladurner Gerald Brandacher Wolfgang Steurer Stefan Schneeberger Claudia Bösmüller Martin Clemens Freund Alfons Kreczy Alfred Königsrainer Raimund Margreiter 《Transplant international》2003,16(12):885-889
Fungal infections still represent a serious complication after organ transplantation. Early diagnosis and aggressive treatment are crucial. Because of the many diagnostic problems involved, we present a case of mucormycosis--primarily affecting the paranasal sinuses with later intracranial extension--in a highly immunized recipient of a third renal transplant. Although fungal infection was suspected from various imaging techniques, only the detection of typical fungal hyphae in the infected tissue was diagnostic. Neither the blood tests and cerebrospinal fluid examinations performed nor cultures from maxillary sinus fluid were of any diagnostic help. Surgical debridement from a transnasal as well as an intracranial approach and systemic amphotericin B together with the discontinuation of immunosuppression after removal of the rejected graft were able to save the patient. This case stresses the importance of early diagnosis that can only be made from tissue biopsies and allows appropriate timely treatment. 相似文献
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Rafael T Mikolajczyk Maren Bredehorst Nadia Khelaifat Claudia Maier Annette E Maxwell 《BMC public health》2007,7(1):21
Background
The prevalence of depression is increasing not only among adults, but also among adolescents. Several risk factors for depression in youth have been identified, including female gender, increasing age, lower socio-economic status, and Latino ethnic background. The literature is divided regarding the role of acculturation as risk factor among Latino youth. We analyzed the correlates of depressive symptoms among Latino and Non-Latino White adolescents residing in California with a special focus on acculturation. 相似文献26.
Sporozoites and free circumsporozoite (CS) protein were stained immunoenzymatically in 1-min saliva samples collected fromAnopheles stephensi mosquitoes infected with eitherPlasmodium berghei orP. falciparum. The number of sporozoites in 1-min saliva-streak samples significantly increased as the salivary gland index rose from 3+ to 4+. ForP. berghei-infected mosquitoes from which saliva had been collected before 30 days postfeed, the median sporozoite counts for 3+ and 4+ gland indexes were 4.5 and 116, respectively. ForP. falciparum-infected mosquitoes, the median counts obtained in two experiments were 4.5 and 14.5 (3+) and 97 and 107 (4+), respectively. The frequency of sporozoite detection in the saliva of mosquitoes containing <100 salivary-gland sporozoites was low (0.1), whereas that in the saliva of mosquitoes with >100 sporozoites was high (0.96). In highly infected 4+P. berghei-infected mosquitoes from which saliva had been collected after 30 days postinfection, both the volume of saliva collected and the median number of sporozoites recovered decreased significantly. 相似文献
27.
Claudia Giaroli Gianfranco Riccò Gianni Vecchi Stefano Belli Caterina Bruno Mario Grignoli Silvia Candela Salvatore Minisci Roberto Poletti Guiseppina Venturi Antonio Ziccardi Pietro Comba 《International archives of occupational and environmental health》1994,66(1):7-11
The present study describes cause-specific mortality of asbestos cement workers in the Emilia Romagna region of Italy. The cohort included workers in ten factories, most of which started operating between 1955 and 1965. Asbestos, mainly chrysotile, constituted 10%–20% of the dry component of the mixture. Crocidolite range between 5% and 50% of total asbestos. Asbestos concentrations up to 44 ff/cc were reported prior to 1975, while in recent years they have usually been below 0–1 ff/cc. The cohort included 3341 workers who had at some time been employed in the ten factories under study. Their mortality experience was compared with that of the population resident in Emilia Romagna. Vital status was ascertained at 1989. Seventy-three subjects were lost to followup (2.2%). Mortality from all causes and from all types of cancer was increased in the cohort. Malignant neoplasms of the respiratory tract showed a significant increase (SMR: 134; 90% confidence interval: 101–175; 40 observed) due to lung cancer (SMR: 124; 90% confidence interval: 91–166; 33 observed) and neoplasms of the pleura, mediastinum, and other parts of the respiratory tract (SMR: 602; 90% confidence interval 237–1267; 5 observed). The discrepancy between observed and expected mortality mainly concerned subjects with at least 20 years of employment in the factories. Five more cases of histologically confirmed mesothelioma occurred after the end of follow-up. 相似文献
28.
Do weekly and fast-rotating shiftwork schedules differentially affect duration and quality of sleep?
F. M. Fischer Antonio Castro Bruni Adelaide Berwerth Claudia Roberta Castro Moreno Rosaneli Lima Fernandez Claudia Riviello 《International archives of occupational and environmental health》1997,69(5):354-360
Characteristics of shiftwork schedules can have distinct impacts on workers’ sleep. This report presents comparisons of the
effects of two different shiftwork schedules on duration and quality of the main sleep episodes in comparable worker populations
at two different petrochemical plants. No significant differences were found for sleep duration in comparing the two plants.
However, within each plant’s shift cycles, morning and night shifts showed shorter sleep durations than all other workdays
and days off. Quality of sleep was perceived as lowest for night shifts of both plant schedules, and of lesser quality for
weekly than for fast-rotating shifts. These results support recommendations for reducing the number of consecutive nights
of shiftwork. However, before recommending any optimal shift schedule, interactions of sleep duration and quality with shift
schedules need much further evaluation.
Received: 18 December 1995/Accepted: 18 July 1996 相似文献
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Dr. Hajo Dirk Weitmann Tomas Hendrik Knocke Claudia Waldhäusl Richard Pötter 《Strahlentherapie und Onkologie》2006,182(2):86-95
BACKGROUND: In advanced vaginal recurrences of cervical and endometrial carcinomas therapeutic options are rare because of preceding therapy. PATIENTS AND METHODS: 23 patients developing advanced vaginal recurrences of cervical and endometrial carcinomas were included. 15 patients started with external-beam therapy to the pelvis and eight patients after preceding radiotherapy underwent brachytherapy alone. All patients had ultrasound-guided implantation of transvaginal or transperineal interstitial needles for brachytherapy. Median prescribed total dose was 64 Gy. RESULTS: 18 patients (78%) achieved complete remission. Six patients are alive without tumor and one with tumor after a median follow-up of 64 months. 14 patients died of tumor and two of intercurrent disease. 5-year disease-specific survival and local control rate were 43% and 47%, respectively, in patients with complete remission. Univariate analysis found time to relapse > 2 years, initial diameter < or = 4 cm, initial volume < 15 cm(3), no extension to the pelvic side wall, volume before brachytherapy < 7.5 cm(3), brachytherapy coverage index > 0.8, and prescribed total dose > 64 Gy being positive predictors for local control and survival. CONCLUSION: The use of ultrasound guidance for placement of interstitial needles in template-based brachytherapy of advanced recurrent gynecologic malignancies is a feasible, safe, and cheap method with encouraging results. Today, ultrasound imaging can be also used to some extent for treatment planning which requires further development. Patient- and treatment-related prognostic factors can be defined. 相似文献