全文获取类型
收费全文 | 2059篇 |
免费 | 125篇 |
国内免费 | 68篇 |
专业分类
耳鼻咽喉 | 8篇 |
儿科学 | 120篇 |
妇产科学 | 28篇 |
基础医学 | 189篇 |
口腔科学 | 47篇 |
临床医学 | 163篇 |
内科学 | 468篇 |
皮肤病学 | 60篇 |
神经病学 | 54篇 |
特种医学 | 290篇 |
外科学 | 256篇 |
综合类 | 85篇 |
预防医学 | 72篇 |
眼科学 | 46篇 |
药学 | 216篇 |
中国医学 | 63篇 |
肿瘤学 | 87篇 |
出版年
2023年 | 17篇 |
2022年 | 34篇 |
2021年 | 61篇 |
2020年 | 32篇 |
2019年 | 35篇 |
2018年 | 69篇 |
2017年 | 41篇 |
2016年 | 54篇 |
2015年 | 48篇 |
2014年 | 74篇 |
2013年 | 103篇 |
2012年 | 91篇 |
2011年 | 99篇 |
2010年 | 70篇 |
2009年 | 70篇 |
2008年 | 67篇 |
2007年 | 96篇 |
2006年 | 72篇 |
2005年 | 81篇 |
2004年 | 51篇 |
2003年 | 53篇 |
2002年 | 47篇 |
2001年 | 59篇 |
2000年 | 49篇 |
1999年 | 49篇 |
1998年 | 59篇 |
1997年 | 68篇 |
1996年 | 64篇 |
1995年 | 61篇 |
1994年 | 35篇 |
1993年 | 42篇 |
1992年 | 20篇 |
1991年 | 22篇 |
1990年 | 27篇 |
1989年 | 49篇 |
1988年 | 43篇 |
1987年 | 36篇 |
1986年 | 22篇 |
1985年 | 26篇 |
1984年 | 13篇 |
1983年 | 13篇 |
1982年 | 18篇 |
1981年 | 21篇 |
1980年 | 19篇 |
1979年 | 18篇 |
1978年 | 8篇 |
1977年 | 17篇 |
1976年 | 10篇 |
1975年 | 10篇 |
1965年 | 2篇 |
排序方式: 共有2252条查询结果,搜索用时 21 毫秒
121.
122.
NU Jerath JS Newman & CJ Boes 《Cephalalgia : an international journal of headache》2009,29(10):1028-1033
The aim of this study was to review the life of Mary E. O'Sullivan and to summarize her important contributions to the study of migraine. Mary E. O'Sullivan underwent extensive training to become a neurologist at a time when only 5% of women in America were physicians. She published five papers on migraine. In a 1936 Journal of the American Medical Association article, she described a patient with ergotamine overuse headache and recommended that daily doses of oral ergotamine should be avoided. Three years later she described migraine as a 'complex' syndrome with multiple causes and multiple cures. Mary E. O'Sullivan, an ambitious female headache specialist of the 1930s, was an early advocate of the use of ergotamine to treat migraine, yet she was one of the first to report ergotamine overuse headache. Although her life was short, her research, knowledge and ambition at a time when women had limited opportunities in medicine have left a mark. 相似文献
123.
Dharamainder Choudhary Ingela Jansson Karim Rezaul David K M Han Mansoor Sarfarazi John B Schenkman 《Drug metabolism and disposition》2007,35(6):987-994
We show, for the first time, the spatiotemporal appearance of Cyp1b1 protein during mouse eye ontogeny. The protein was unambiguously identified in the adult mouse eye and newborn (P0) whole mouse microsomes and was shown to be localized in inner ciliary epithelium, corneal epithelium, retinal inner nuclear cells, and ganglion cells. The enzyme protein was present in the lens epithelium adjacent to the developing ciliary body at 15.5 days postconception (E15.5) and was most strongly expressed during E17.5 to 7 days postnatally (P07). Subsequently, it declined to very low levels. The protein was also expressed in the corneal endothelial cells adjacent to the ciliary body at P07. Cyp1b1 was barely detectable in the inner ciliary epithelium before E17.5 but increased rapidly postnatally, reaching adult levels by P28. Levels of the enzyme protein in the corneal epithelium were seen from E15.5 onward, increasing sharply, and after a decrease at P07, were highest in the adult animal eye. The presence of Cyp1b1 protein in the inner nuclear layer of the retina was very low in the prenatal eye, increasing rapidly postnatally, and was highest in the adult animal eye. In the ganglion cell layer of the retina, it increased slowly from E15.5 to P07 and then rapidly reached adult levels. Interestingly, Cyp1b1 was not detected in the trabecular meshwork at any stage of development or in the adult eye. We conclude that the enzyme may play important roles in normal eye development and function in mice as in humans, and that the mouse may prove to be an excellent model for determination of the roles of CYP1B1 in human eye development and function. 相似文献
124.
Rhinophyma is a common condition in the west of Scotland. Various surgical approaches have been described, most of which rely heavily on electrocautery, heated scalpel, or laser coagulation for hemostasis, resulting in thermal injury and substantial risk of scarring. The authors describe their experience with the "triple approach" for the surgical treatment of rhinophyma, consisting of tangential excision for debulking, the use of scissors for sculpting, and the use of mild dermabrasion for final contouring. The use of an alginate hemostatic dressing is also described. The triple approach has been used in 6 patients with pleasing results. 相似文献
125.
A new coumarin from Murraya paniculata 总被引:1,自引:0,他引:1
A new natural product, 2'-O-ethylmurrangatin (1) was isolated along with two previously known compounds murranganone (2) and paniculatin (3) from the leaves of Murraya paniculata. The structure of compound 1 was elucidated with the help of spectroscopic studies and by chemical reactions. Compounds 2 and 3 have been found to be cholinesterase inhibitors. 相似文献
126.
Durairaj M Sharma R Choudhary SK Bhan A Venugopal P 《The Annals of thoracic surgery》2002,74(3):931-932
A 12-year-old child with chronic pleural effusions for a month and a half after a fenestrated Fontan operation underwent bilateral diaphragmatic fenestrations with complete relief. We suggest this approach as an alternative treatment for chronic pleural effusions that may ensue after total cavopulmonary connection. 相似文献
127.
128.
129.
130.