全文获取类型
收费全文 | 1833篇 |
免费 | 123篇 |
国内免费 | 25篇 |
专业分类
耳鼻咽喉 | 11篇 |
儿科学 | 46篇 |
妇产科学 | 22篇 |
基础医学 | 214篇 |
口腔科学 | 35篇 |
临床医学 | 149篇 |
内科学 | 399篇 |
皮肤病学 | 45篇 |
神经病学 | 138篇 |
特种医学 | 126篇 |
外科学 | 159篇 |
综合类 | 11篇 |
预防医学 | 82篇 |
眼科学 | 78篇 |
药学 | 145篇 |
2篇 | |
中国医学 | 10篇 |
肿瘤学 | 309篇 |
出版年
2023年 | 15篇 |
2022年 | 35篇 |
2021年 | 57篇 |
2020年 | 32篇 |
2019年 | 36篇 |
2018年 | 42篇 |
2017年 | 43篇 |
2016年 | 55篇 |
2015年 | 65篇 |
2014年 | 77篇 |
2013年 | 75篇 |
2012年 | 143篇 |
2011年 | 144篇 |
2010年 | 93篇 |
2009年 | 80篇 |
2008年 | 107篇 |
2007年 | 135篇 |
2006年 | 106篇 |
2005年 | 104篇 |
2004年 | 92篇 |
2003年 | 75篇 |
2002年 | 72篇 |
2001年 | 9篇 |
2000年 | 13篇 |
1999年 | 20篇 |
1998年 | 36篇 |
1997年 | 29篇 |
1996年 | 21篇 |
1995年 | 17篇 |
1994年 | 19篇 |
1993年 | 18篇 |
1992年 | 4篇 |
1991年 | 3篇 |
1989年 | 21篇 |
1988年 | 15篇 |
1987年 | 8篇 |
1986年 | 6篇 |
1985年 | 6篇 |
1984年 | 6篇 |
1983年 | 5篇 |
1982年 | 8篇 |
1981年 | 6篇 |
1980年 | 7篇 |
1979年 | 1篇 |
1978年 | 3篇 |
1977年 | 4篇 |
1976年 | 4篇 |
1975年 | 5篇 |
1953年 | 1篇 |
1937年 | 1篇 |
排序方式: 共有1981条查询结果,搜索用时 31 毫秒
61.
62.
63.
64.
Ushiki T Nikkuni K Yoshida C Shibasaki Y Ishikawa T Masuko M Takai K 《[Rinshō ketsueki] The Japanese journal of clinical hematology》2012,53(1):97-104
A 35-year-old man admitted to the hospital for oral hemorrhage was diagnosed with acute promyelocytic leukemia (APL). Remission from APL was achieved by induction therapy with all-trans retinoic acid (ATRA); the PML/RARA fusion gene was not detected on PCR analysis. Despite complete molecular remission, severe persistent pancytopenia, massive ascites, and renal failure were observed. The liver surface appeared rough and irregular on computed tomographic images. On the basis of the liver biopsy results, we diagnosed his condition as portal hypertension due to autoimmune hepatitis. Indocyanine green test showed good residual function of the liver, and therefore, 2 courses of consolidation therapy were administered; chemotherapy was stopped because of severe pancytopenia due to portal hypertension. Instead of continuing the consolidation therapy, maintenance therapy involving 8 rounds of ATRA monotherapy (45 mg/m(2), days1~14) was initiated. Portal hypertension did not progress further with this maintenance therapy and therefore it was continued. The patient has been in remission from APL ever since, and no relapses have occurred since the past 5 years. These results suggest that ATRA can be used for long-term therapy in such cases. 相似文献
65.
66.
67.
Takatsugu Yamamoto Yukiko Kurashima Chie Watanabe Kazunori Ohata Ryoya Hashiba Shogo Tanaka Takahiro Uenishi Koichi Ohno 《International surgery》2013,98(4):412-415
A 75-year-old woman with a history of myocardial infarction, gallstones, and right renal cancer was referred to our department because of right flank pain. She had a surgical scar on the right abdomen between the 10th and 11th ribs; computed tomography demonstrated intercostal herniation of the colon. Recognizing the possibility of adhesions of the hernia and colon, we used a median skin incision and patched a polyester mesh coated with absorbent collagen. The patient had an uneventful postoperative course, with no pain for 6 months postoperatively. Transdiaphragmatic intercostal hernias with abdominal contents commonly develop after trauma or thoracic surgery. Incisional intercostal hernias seldom develop after nephrectomy; the present case is only the fourth report. We conjecture that a costochondral incision can induce subluxation of the costotransverse joint, intercostal nerve injury, and atrophy of the intercostal and abdominal oblique muscles. Surgeons must therefore recognize the potential, albeit rare, for intercostal hernia after nephrectomy. 相似文献
68.
Chie Shimizu Takayuki Fujita Yoshinobu Fuke Minako Yabuki Mamiko Kajiwara Seiichiro Hemmi Atsushi Satomura Masayoshi Soma 《International urology and nephrology》2013,45(3):803-808
Purpose
Cyclosporine (CsA) is often prescribed to patients with glucocorticoid (GC)-dependent nephrotic syndrome. Although it is well known that long-term administration of GC causes osteoporosis, the effects of CsA on bone metabolism are not fully established. Therefore, we examined the effects of CsA on bone metabolism in patients with GC-dependent nephrotic syndrome in remission.Methods
We followed 23 patients treated with prednisolone alone (GC alone group) and 17 patients treated with CsA in combination with prednisolone (GC + CsA group). Bone mineral density (BMD) was measured by dual-energy X-ray absorptiometry, and biochemical markers of bone metabolism were simultaneously measured in serum and urine samples.Results
BMD decreased significantly in the GC group from 752 to 623 mg/cm2 but non-significantly in the GC + CsA group from 751 to 684 mg/cm2. Although the cumulative dose of GC increased in both groups, there were no significant differences in biochemical markers at either the start or the end of the study. Vertebrate bone fracture and other side effects associated with CsA treatment did not occur in our study.Conclusions
Our results indicate that CsA does not accelerate GC-induced osteoporosis in patients with nephrotic syndrome. We conclude that CsA is appropriate for the treatment of GC-dependent nephrotic syndrome, because it does not adversely affect bone metabolism and has favorable glomerular effects. 相似文献69.
70.
T Ikezoe J Yang C Nishioka G Honda M Furihata A Yokoyama 《Arteriosclerosis, thrombosis, and vascular biology》2012,32(9):2259-2270