全文获取类型
收费全文 | 2792篇 |
免费 | 178篇 |
国内免费 | 19篇 |
专业分类
耳鼻咽喉 | 11篇 |
儿科学 | 56篇 |
妇产科学 | 68篇 |
基础医学 | 298篇 |
口腔科学 | 54篇 |
临床医学 | 192篇 |
内科学 | 567篇 |
皮肤病学 | 43篇 |
神经病学 | 77篇 |
特种医学 | 309篇 |
外科学 | 330篇 |
综合类 | 215篇 |
一般理论 | 3篇 |
预防医学 | 175篇 |
眼科学 | 306篇 |
药学 | 112篇 |
中国医学 | 1篇 |
肿瘤学 | 172篇 |
出版年
2023年 | 26篇 |
2022年 | 47篇 |
2021年 | 99篇 |
2020年 | 42篇 |
2019年 | 61篇 |
2018年 | 70篇 |
2017年 | 43篇 |
2016年 | 64篇 |
2015年 | 47篇 |
2014年 | 80篇 |
2013年 | 112篇 |
2012年 | 129篇 |
2011年 | 139篇 |
2010年 | 69篇 |
2009年 | 70篇 |
2008年 | 143篇 |
2007年 | 130篇 |
2006年 | 119篇 |
2005年 | 135篇 |
2004年 | 125篇 |
2003年 | 114篇 |
2002年 | 106篇 |
2001年 | 117篇 |
2000年 | 94篇 |
1999年 | 84篇 |
1998年 | 33篇 |
1997年 | 34篇 |
1996年 | 32篇 |
1995年 | 33篇 |
1994年 | 29篇 |
1993年 | 21篇 |
1992年 | 35篇 |
1991年 | 35篇 |
1990年 | 39篇 |
1989年 | 34篇 |
1988年 | 48篇 |
1987年 | 42篇 |
1986年 | 39篇 |
1985年 | 45篇 |
1984年 | 17篇 |
1983年 | 29篇 |
1982年 | 21篇 |
1981年 | 11篇 |
1980年 | 11篇 |
1979年 | 12篇 |
1978年 | 18篇 |
1977年 | 15篇 |
1976年 | 19篇 |
1972年 | 11篇 |
1970年 | 10篇 |
排序方式: 共有2989条查询结果,搜索用时 46 毫秒
991.
992.
993.
Clarissa S.M. Cheng Srinivasan Sanjay Chee Chew Yip Heng-Wai Yuen 《Saudi Journal of Ophthalmology》2012,26(4):459-461
Sphenoidal sinus mucoceles are indolent lesions that, when sufficiently large, can compress on the optic canal or superior orbital fissure, rapidly causing loss of vision, optic neuropathy, ptosis, pain, ophthalmoplegia, and diplopia. We herein report a 72-year-old gentleman who presented acutely with Cranial Nerve II, III, and IV palsies secondary to a sphenoidal sinus mucocele that was confirmed on magnetic resonance imaging and successfully treated with endoscopic drainage. This cause of orbital apex syndrome is important for clinicians to know as early diagnosis and treatment is critical in recovering visual potential. 相似文献
994.
Sport Sciences for Health - The research aims to examine the effects of fructooligosaccharide (FOS) concentrations on the physicochemical properties of formulated sports drinks (FSDs) and the... 相似文献
995.
Yael Kusne Emily L. Goldberg Sara S. Parker Sophie M. Hapak Irina Y. Maskaykina Wade M. Chew Kirsten H. Limesand Heddwen L. Brooks Theodore J. Price Nader Sanai Janko Nikolich-Zugich Sourav Ghosh 《Age (Dordrecht, Netherlands)》2014,36(1):199-212
The chronic and systemic administration of rapamycin extends life span in mammals. Rapamycin is a pharmacological inhibitor of mTOR. Metformin also inhibits mTOR signaling but by activating the upstream kinase AMPK. Here we report the effects of chronic and systemic administration of the two mTOR inhibitors, rapamycin and metformin, on adult neural stem cells of the subventricular region and the dendate gyrus of the mouse hippocampus. While rapamycin decreased the number of neural progenitors, metformin-mediated inhibition of mTOR had no such effect. Adult-born neurons are considered important for cognitive and behavioral health, and may contribute to improved health span. Our results demonstrate that distinct approaches of inhibiting mTOR signaling can have significantly different effects on organ function. These results underscore the importance of screening individual mTOR inhibitors on different organs and physiological processes for potential adverse effects that may compromise health span. 相似文献
996.
997.
998.
Thapa MM Chaturvedi A Iyer RS Darling SE Khanna PC Ishak G Chew FS 《AJR. American journal of roentgenology》2012,198(5):W456-W465
OBJECTIVE: The purpose of this article is to discuss MRI of the pediatric knee and familiarize the reader with conditions encountered in the pediatric population. Clinical scenarios are included to convey important concepts and to orient the learner to normal variants and abnormalities of the pediatric knee. The conditions discussed include, but are not limited to, distal femoral metaphysial irregularity, isolated popliteus tendon avulsion, juvenile idiopathic arthritis, and discoid meniscus. CONCLUSION: The knee is the joint that is most commonly imaged by MRI in children. Injury patterns and signs of other pathologic processes seen in skeletally immature patients are different from those seen in adults. Interpreting pediatric knee MRI studies may be a challenge for those unfamiliar with the evolving patterns of normal development and of the signs of conditions that are more prevalent in children. Through case scenarios, this article describes and provides images that depict conditions commonly encountered in the pediatric knee. Most of the described normal findings and abnormalities are more prevalent in the pediatric population than in adults, and a few of the conditions are, in fact, unique to pediatric patients. 相似文献
999.
OBJECTIVE: This article reviews the imaging features of revisions and complications of hip replacement arthroplasty and relates these features to the current understanding about how and why these failures occur. CONCLUSION: Short-term failures of hip replacements are most commonly the result of instability and dislocation. Complications ranging from osteolysis caused by granulomatous reaction to particulate wear debris lead to many long-term failures. Attempts to reduce wear debris through changes in design and materials have reduced the rate of some complications but have resulted in new ones. Infection remains a devastating complication that is difficult to resolve. 相似文献
1000.
Normal squamous epithelial cells readily undergo terminal differentiation in culture and are commonly used in differentiation studies. Several intracellular markers of squamous differentiation such as keratin, involucrin, transglutaminase and cholesterol sulfate have been well-studied and described by other workers. We have recently reported a surface membrane antigen in squamous carcinoma of the head and neck antigen in squamous carcinoma of the head and neck which is recognized by a murine monoclonal antibody SQMI. In this paper, we present our studies on the ultrastructural localization of SQMI antigen in cultured squamous epithelial cells using gold-labelled antibody. The cells studied included both normal and cancer cells at different degrees of differentiation. Under both transmission and scanning electron microscopy examination, the SQMI antigen was localized at the membrane surface of cultured cells, particularly at sites of cell-cell interdigitation. No association with desmosomal structure was observed in any of the specimens examined. There was however an association of SQMI antigen with microvilli of cell membrane. No non-specific cytoplasmic localization of SQMI antigen was observed. The intensity of SQM1 antigen revealed by gold-labelling appeared to have a positive correlation with the degree of differentiation of the cells in culture. 相似文献