全文获取类型
收费全文 | 61210篇 |
免费 | 5682篇 |
国内免费 | 3492篇 |
专业分类
耳鼻咽喉 | 511篇 |
儿科学 | 875篇 |
妇产科学 | 1005篇 |
基础医学 | 7019篇 |
口腔科学 | 1085篇 |
临床医学 | 7175篇 |
内科学 | 9893篇 |
皮肤病学 | 733篇 |
神经病学 | 2917篇 |
特种医学 | 2527篇 |
外国民族医学 | 34篇 |
外科学 | 7342篇 |
综合类 | 9088篇 |
现状与发展 | 15篇 |
一般理论 | 16篇 |
预防医学 | 3966篇 |
眼科学 | 1485篇 |
药学 | 6572篇 |
53篇 | |
中国医学 | 3078篇 |
肿瘤学 | 4995篇 |
出版年
2024年 | 176篇 |
2023年 | 843篇 |
2022年 | 2081篇 |
2021年 | 2861篇 |
2020年 | 2065篇 |
2019年 | 1890篇 |
2018年 | 2031篇 |
2017年 | 1807篇 |
2016年 | 1800篇 |
2015年 | 2495篇 |
2014年 | 3156篇 |
2013年 | 3175篇 |
2012年 | 4448篇 |
2011年 | 4723篇 |
2010年 | 3068篇 |
2009年 | 2517篇 |
2008年 | 3363篇 |
2007年 | 3463篇 |
2006年 | 3176篇 |
2005年 | 2974篇 |
2004年 | 2392篇 |
2003年 | 2208篇 |
2002年 | 2003篇 |
2001年 | 1675篇 |
2000年 | 1604篇 |
1999年 | 1445篇 |
1998年 | 780篇 |
1997年 | 794篇 |
1996年 | 647篇 |
1995年 | 540篇 |
1994年 | 470篇 |
1993年 | 321篇 |
1992年 | 509篇 |
1991年 | 414篇 |
1990年 | 388篇 |
1989年 | 350篇 |
1988年 | 276篇 |
1987年 | 260篇 |
1986年 | 206篇 |
1985年 | 161篇 |
1984年 | 117篇 |
1983年 | 84篇 |
1982年 | 60篇 |
1981年 | 73篇 |
1980年 | 39篇 |
1979年 | 73篇 |
1978年 | 37篇 |
1974年 | 36篇 |
1973年 | 33篇 |
1972年 | 41篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
白细胞介素4(IL-4)是T辅助2(Th2)介导的免疫反应的基本免疫调节细胞因子,IL-4具有复杂的信号系统和多效的功能,但在脑组织中,诸多研究发现IL-4可在炎症中保护认知功能。该文总结了关于IL-4保护认知功能的证据及机制,以及在阿尔茨海默病、缺血性脑血管病以及手术后认知功能障碍中IL-4保护认知功能的途径及证据。 相似文献
12.
Chen Rong Zhang Yuan Huang Lei Cheng Bi-heng Xia Zhong-yuan Meng Qing-tao 《Journal canadien d'anesthésie》2020,67(6):655-663
Canadian Journal of Anesthesia/Journal canadien d'anesthésie - To assess the management and safety of epidural or general anesthesia for Cesarean delivery in parturients with coronavirus... 相似文献
13.
14.
15.
目的回顾我院药物代谢酶和药物作用靶点相关基因检测与精准药学服务实践过程,总结经验,与同行分享。方法从准备工作、相关检测项目的确定,学术推广、项目优化和开展情况等方面详细阐述我院基因检测开展过程与精准药学服务情况。结果根据临床需求,我院已开展了以心脑血管药和抗精神病药为主的27种药物,26项检测,2018年全年位1587名患者提供个体化用药建议,受到临床医生和患者欢迎。结论基于代谢酶和药物作用靶点相关基因检测的个体化用药建议是临床药师参与精准治疗的重要途径,有助于医生和药师之间的沟通,有利于提高药学服务水平。 相似文献
16.
OBJECTIVES: To assess the effectiveness and safety of additional bedtime H2‐receptor antagonists (H2RAs) in suppressing nocturnal gastric acid breakthrough (NAB) via a systematic review. METHODS: Eligible trials were identified by searching the Cochrane Central Register of Controlled Trials (CENTRAL) (Cochrane Library Issue 2, 2004), MEDLINE (January 1966–June 2004), EMBASE (January 1980–June 2004) and CINAHL (January 1982–June 2004). Additional hand‐searching was conducted on the proceedings of correlated conferences, eight important Chinese journals and references of all included trials. All randomized controlled trials evaluating H2RAs for the control of NAB were eligible for inclusion. The systematic review was conducted using methods recommended by The Cochrane Collaboration. RESULTS: Only two randomized crossover studies, comprising 32 participants, met the inclusion criteria. Because the design, dosage and duration of the treatments were different between the studies, it was not possible to conduct meta‐analysis. There were no consistent conclusions found between the two included studies in evaluating H2RAs for the control of NAB. CONCLUSIONS: No implications for practice at this stage can be concluded. Appropriately designed large‐scale randomized controlled trials with long‐term follow up are needed to determine the effects of additional bedtime H2RAs in suppressing NAB. 相似文献
17.
Meng Qingyue Li Renzhong Cheng Gang 《中国防痨杂志》2003,25(Z1):22-23
INTRODUCTION: The financial responsibility in health sector was decentralizedfrom central and provincial governments to county and township governments. It was argued that a decentralized system without effective transfer payment mechanism has pushed the poverty area to more disadvantaged positions in economic development in general. 相似文献
18.
Mei-Ju Chen Ching-Yu Cheng Yen-Cheng Chen Ching-Kuang Chou Wen-Ming Hsu 《Journal of ocular pharmacology and therapeutics》2006,22(3):188-193
PURPOSE: The aim of this study was to investigate the effects of bimatoprost 0.03% on ocular hemodynamics in patients with normal tension glaucoma (NTG). METHODS: Twenty-two (22) patients with NTG were consecutively recruited. After basic eye examination and diurnal intraocular pressure (IOP) measurement, color Doppler imaging was used to measure the peak systolic and end diastolic velocities and resistive index of the central retinal, lateral posterior ciliary, and medial posterior ciliary arteries. Patients received bimatoprost 0.03% for 4 weeks, and these measurements were then repeated. The worse eye of each NTG patient was used in the statistical analysis. RESULTS: Bimatoprost 0.03% significantly reduced mean IOP from 15.1 +/- 3.8 mmHg at baseline to 12.0 +/- 2.9 mmHg after treatment in our sample of NTG patients (P < 0.001). No significant changes in blood velocities or resistance indices were observed in the retrobulbar vessels after the 4-week treatment. CONCLUSIONS: Topical bimatoprost 0.03% significantly reduced IOP in our NTG patients without causing significant hemodynamic changes in the retrobulbar vessels. 相似文献
19.
外科学教学中的审美教育 总被引:1,自引:0,他引:1
医学审美教育是医学生全面素质教育不可分割的组成部分,笔者结合长期外科教学实践,阐述了在外科学教学中运用医学美学原理对外科学的美进行开发和挖掘,使医学生在熟练掌握外科学基本理论和基本技能的同时,潜移默化地接受美的教育,美的熏陶,更能激发他们对外科学的热爱和兴趣,达到全面提高医学生整体素质的目的。 相似文献
20.
Pulmonary Lophomonas blattarum infection in patients with kidney allograft transplantation 总被引:3,自引:0,他引:3
Yong Wang Zheng Tang Shuming Ji Zhen Zhang Jinsong Chen Zhen Cheng Dongrui Cheng Zhihong Liu Leishi Li 《Transplant international》2006,19(12):1006-1013
The aim of the study was to analyse the clinical manifestation and management of pulmonary Lophomonas blattarum infection in four allograft transplantation recipients retrospectively. Four patients with pulmonary L. blattarum infection were diagnosed by using Fiberoptic bronchoscopy (FOB) and bronchoalveolar lavage (BAL) examination. Their clinical manifestation and management are summarized. Four cases of pulmonary L. blattarum were found during the period from the second month to the third month after transplantation. Concurring infection by other pathogens was found in three of them. Common initial symptoms included fever (>38 degrees C) without cough and breathlessness. Lower lobe shadowing could be found on chest X-ray. Body temperature decreased to the normal range in three patients and to 37.5 degrees C in the other one, after intravenous injection of metronidazole and tapering immunosuppressant. Radiological examination confirmed improved health condition of the patients afterwards. Two patients received repeated FOB and only dead L. blattarum was found. Pulmonary L. blattarum infection in allograft transplant recipients carry relatively obscure initial symptoms. Possible L. blattarum infection needs to be screened in post-transplantation pulmonary infection patients with similar symptoms, especially in those who respond poorly to anti-infection treatment. Microscopic examination of BAL fluid can help to identify pulmonary L. blattarum infection and metronidazole is an ideal treatment choice. 相似文献