全文获取类型
收费全文 | 901篇 |
免费 | 43篇 |
国内免费 | 24篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 32篇 |
妇产科学 | 18篇 |
基础医学 | 79篇 |
口腔科学 | 21篇 |
临床医学 | 113篇 |
内科学 | 263篇 |
皮肤病学 | 41篇 |
神经病学 | 62篇 |
特种医学 | 105篇 |
外科学 | 33篇 |
综合类 | 72篇 |
预防医学 | 46篇 |
眼科学 | 20篇 |
药学 | 31篇 |
中国医学 | 2篇 |
肿瘤学 | 29篇 |
出版年
2022年 | 5篇 |
2021年 | 9篇 |
2020年 | 6篇 |
2018年 | 8篇 |
2017年 | 8篇 |
2016年 | 17篇 |
2015年 | 13篇 |
2014年 | 23篇 |
2013年 | 63篇 |
2012年 | 17篇 |
2011年 | 24篇 |
2010年 | 32篇 |
2009年 | 34篇 |
2008年 | 13篇 |
2007年 | 42篇 |
2006年 | 17篇 |
2005年 | 16篇 |
2004年 | 14篇 |
2003年 | 16篇 |
2002年 | 12篇 |
2001年 | 15篇 |
2000年 | 17篇 |
1999年 | 15篇 |
1998年 | 51篇 |
1997年 | 47篇 |
1996年 | 36篇 |
1995年 | 26篇 |
1994年 | 31篇 |
1993年 | 35篇 |
1992年 | 6篇 |
1991年 | 8篇 |
1990年 | 14篇 |
1989年 | 35篇 |
1988年 | 20篇 |
1987年 | 23篇 |
1986年 | 15篇 |
1985年 | 7篇 |
1984年 | 9篇 |
1983年 | 7篇 |
1982年 | 9篇 |
1981年 | 10篇 |
1980年 | 10篇 |
1977年 | 5篇 |
1976年 | 7篇 |
1975年 | 6篇 |
1963年 | 6篇 |
1962年 | 5篇 |
1960年 | 5篇 |
1955年 | 4篇 |
1941年 | 11篇 |
排序方式: 共有968条查询结果,搜索用时 609 毫秒
41.
Siriporn C. Chattipakorn Savitree Thummasorn Jantira Sanit Nipon Chattipakorn 《老年心脏病学杂志》2014,11(2):151-157
Background Cilostazol is a type 3 phosphodiesterase inhibitor which has been previously demonstrated to prevent the occurrence of tachyarrhythmia and improve defibrillation efficacy. However, the mechanism for this beneficial effect is still unclear. Since cardiac mito-chondria have been shown to play a crucial role in fatal cardiac arrhythmias and that oxidative stress is one of the main contributors to arr-hythmia generation, we tested the effects of cilostazol on cardiac mitochondria under severe oxidative stress. Methods Mitochondria were isolated from rat hearts and treated with H2O2 to induce oxidative stress. Cilostazol, at various concentrations, was used to study its protective effects. Pharmacological interventions, including a mitochondrial permeability transition pore (mPTP) blocker, cyclosporine A (CsA), and an inner membrane anion channel (IMAC) blocker, 4'-chlorodiazepam (CDP), were used to investigate the mechanistic role of cilostazol on cardiac mitochondria. Cardiac mitochondrial reactive oxygen species (ROS) production, mitochondrial membrane potential change and mi-tochondrial swelling were determined as indicators of cardiac mitochondrial function. Results Cilostazol preserved cardiac mitochondrial function when exposed to oxidative stress by preventing mitochondrial depolarization, mitochondrial swelling, and decreasing ROS produc-tion. Conclusions Our findings suggest that cardioprotective effects of cilostazol reported previously could be due to its prevention of car-diac mitochondrial dysfunction caused by severe oxidative stress. 相似文献
42.
BAROREFLEX MECHANISMS IN HYPERTENSION 总被引:2,自引:0,他引:2
43.
44.
45.
46.
Ian Freckelton SC 《Psychiatry, Psychology and Law》2013,20(1):171-173
The role of the community management order (CMO) in the management of mental illness has been associated with controversy. There is uncertainty as to the effectiveness of such involuntary treatment. Review of outcomes of involuntary community treatment has shown varied results, and in the remote areas of Australia the issue becomes more complex, and outcomes more difficult to measure. The Northern Territory's Mental Health Act 2000 has broadened criteria for detention. The decision to impose follow-up and case management on an individual (who may reside in a community several hundred kilometres from an in-patient facility) requires careful consideration of its ethical, professional and psychosocial implications. The trend toward increasing use of mental health legislation in the Northern Territory — particularly for Indigenous people — deserves close scrutiny in order that culturally appropriate and sensitive treatment plans are developed. 相似文献
47.
48.
49.
50.
Cocaine use in pregnancy in Amsterdam 总被引:1,自引:0,他引:1
BJ Smit K Boer AM van Huis ISE Lie-A-Ling SC Schmidt 《Acta paediatrica (Oslo, Norway : 1992)》1994,83(S404):32-35
To study the effects of cocaine use in pregnancy in Amsterdam, clinical data on cocaine-using pregnant women ( n = 21) and their offspring ( n = 23) were obtained retrospectively (1987–1994) at the Academic Medical Center, Amsterdam. Infants exposed to cocaine had a median gestational age of 39 weeks and a median birth weight of 3090 g. There were six preterm infants, two small-for-gestational-age infants and five infants with a small head circumference. Three infants had a congenital malformation. One infant (Potter's syndrome) died shortly before birth. One infant had congenital syphilis, four had intracerebral abnormalities on ultrasound and four had abnormal neurologic symptoms in the neonatal period. One infant died after 21 days of life. At follow-up four infants showed abnormal development. In 12 of the 23 infants (52%), one or more possible effects of cocaine were found. 相似文献