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101.
Mortera C Rissech M Bartrons J Carretero J Prada F 《Revista espa?ola de cardiología》2005,58(5):592-595
We report our experience with stenting of the ductus arteriosus in three neonates. Two patients had pulmonary atresia with an intact interventricular septum and one had critical pulmonary stenosis. Radiofrequency ablation was used to open the atretic pulmonary valve in two patients. In all three patients implanting a stent avoided the need for surgical creation of a Blalock-Taussig shunt. In two patients the procedure was scheduled as elective surgery, and in one it was done as an emergency procedure. Ductus arteriosus stenting is an alternative to palliative cardiac surgery. 相似文献
102.
Martínez I Rosa M Arsuaga JL Jarabo P Quam R Lorenzo C Gracia A Carretero JM Bermúdez de Castro JM Carbonell E 《Proceedings of the National Academy of Sciences of the United States of America》2004,101(27):9976-9981
Human hearing differs from that of chimpanzees and most other anthropoids in maintaining a relatively high sensitivity from 2 kHz up to 4 kHz, a region that contains relevant acoustic information in spoken language. Knowledge of the auditory capacities in human fossil ancestors could greatly enhance the understanding of when this human pattern emerged during the course of our evolutionary history. Here we use a comprehensive physical model to analyze the influence of skeletal structures on the acoustic filtering of the outer and middle ears in five fossil human specimens from the Middle Pleistocene site of the Sima de los Huesos in the Sierra de Atapuerca of Spain. Our results show that the skeletal anatomy in these hominids is compatible with a human-like pattern of sound power transmission through the outer and middle ear at frequencies up to 5 kHz, suggesting that they already had auditory capacities similar to those of living humans in this frequency range. 相似文献
103.
Casaretto C Martínez Sarrasague M Giuliano S Rubin de Celis E Gambarotta M Carretero I Miragaya M 《Andrologia》2012,44(Z1):335-341
Llama semen is highly viscous. This characteristic is usually evaluated subjectively by measuring the thread formed when carefully pippeting a sample of semen. The aims of this study were (i) to objectively determine and analyse llama semen viscosity, (ii) to compare semen viscosity between ejaculates of the same male as well as between different males, (iii) to study the correlation between viscosity and other semen characteristics and (iv) to evaluate the effect of collagenase on semen viscosity. Semen viscosity was evaluated using a cone-plate Brookfield rotational viscometer. A non Newtonian, pseudoplastic behaviour was observed in the 45 semen samples evaluated. Rheological parameters were determined obtaining the following results (mean ± SD): apparent viscosity at 11.5 s(-1): 46.71 ± 26.8 cpoise and at 115 s(-1): 12.61 ± 4.1 cpoise; structural viscosity (K) (dyne s cm(-2)): 2.18 ± 1.4 and coefficient of consistency (n): 0.45 ± 0.1. Statistical differences were found between different ejaculates of the same male for structural viscosity and apparent viscosity at 11.5 s(-1) (P < 0.01). Correlation was found only between coefficient of consistency (n) and sperm concentration (P < 0.01). Significant differences for coefficient of consistency (n) and viscosity at 115 s(-1) were found between samples incubated with and without collagenase (P < 0.05). 相似文献
104.
105.
OA Adaramoye 《African health sciences》2012,12(4):498-506
Background
Hypoglycaemic effect of kolaviron (KV), (biflavonoid from Garcinia kola) in streptozotocin (STZ)-diabetic rats has been established.Objectives
To evaluate the possible protective effects of KV on cardiac, renal and hepatic tissues of STZ-diabetic rats.Methods
This study consists of four groups of 6 rats each. Groups one and two contained non-diabetic and untreated-diabetic rats, respectively. Groups three and four were made up of KV- and glibenclamide (GB) - treated diabetic rats, respectively.Results
STZ-intoxication caused a significant (p<0.05) increase in the relative weight of liver in diabetic rats. STZ-diabetic rats had significant increase (p<0.05) in the levels of fasting blood glucose (FBG), á-amylase and HbA1c. A marked and significant (p<0.05) increase in the levels of cardiac, renal and liver marker indices such as serum creatine kinase, lactate dehydrogenase, creatinine, urea and alanine aminotransferase were observed in untreated diabetic rats. Also, untreated diabetic rats had significantly (p<0.05) elevated urinary glucose and protein and, lowered creatinine clearance. In KV- and GB- treated groups, the levels of FBG, á-amylase and HbA1c were significantly (p<0.05) reduced, while treatment with KV significantly (p<0.05) attenuated the cardiac, renal and liver marker indices.Conclusion
KV offered significant antidiabetic and tissues protective effects in the rats. 相似文献106.
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109.
Research in psychopharmacology for children and adolescents is fraught with ethical problems and tensions. This has practical
consequences as it leads to a paucity of the research that is essential to support the treatment of this vulnerable group.
In this article, we will discuss some of the ethical issues which are relevant to such research, and explore their implications
for both research and standard care. We suggest that finding a way forward requires a willingness to acknowledge and discuss
the inherent conflicts between the ethical principles involved. Furthermore, in order to facilitate more, ethically sound
psychopharmacology research in children and adolescents, we suggest more ethical analysis, empirical ethics research and ethics
input built into psychopharmacological research design. 相似文献
110.
OA Dr. med. Matthias Richter P. Macchiarini W. Harringer 《Zeitschrift für Herz-, Thorax- und Gef??chirurgie》2008,22(2):103-109
Lung cancer is one of the most common cancers in industrialized nations, dominating in men but also increasing continuously in women. Complete surgical resection of the tumor remains the only curative therapy. A surgical approach requires precise preoperative diagnostic evaluation and staging of the carcinoma as well as the interdisciplinary discussion to determine the individual therapeutic treatment. Surgical therapy of lung cancer is stage dependent and often part of a multimodal approach including adjuvant or neoadjuvant radio- and/or chemotherapy. Close communication with associated specialties is mandatory. Surgical considerations for therapeutic strategies in different lung cancer stages are presented and indications for tumor resections are described. Furthermore, invasive staging techniques are discussed and preoperative evaluation of pulmonary function and its implications on extent of surgical resection are explained. 相似文献