Carlo Gambacorti‐Passerini  Clara Chen  Catherine Davis  Ginny P. Sen  Christy Guyan  Rüdiger Hehlmann  Mauricette Michallet  Ronald Paquette  Stuart L. Goldberg 《European journal of haematology》2021,106(1):82-89

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Antonio Pesce  Gaetano Piccolo  Francesca Lecchi  Nicol&#  Fabbri  Michele Diana  Carlo Vittorio Feo 《World journal of gastroenterology : WJG》2021,27(36):5989-6003

Laparoscopic cholecystectomy (LC) is one of the most frequently performed gastrointestinal surgeries worldwide. Bile duct injury (BDI) represents the most serious complication of LC, with an incidence of 0.3%-0.7%, resulting in significant perioperative morbidity and mortality, impaired quality of life, and high rates of subsequent medico-legal litigation. In most cases, the primary cause of BDI is the misinterpretation of biliary anatomy, leading to unexpected biliary lesions. Near-infrared fluorescent cholangiography is widely spreading in clinical practice to delineate biliary anatomy during LC in elective and emergency settings. The primary aim of this article was to perform an up-to-date overview of the evolution of this method 12 years after the first clinical application in 2009 and to highlight all advantages and current limitations according to the available scientific evidence.  相似文献   

    

Carlo Romano Settanni  Gianluca Ianiro  Francesca Romana Ponziani  Stefano Bibb&#  Jonathan Philip Segal  Giovanni Cammarota  Antonio Gasbarrini 《World journal of gastroenterology : WJG》2021,27(43):7433-7445

In December 2019 a novel coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), started spreading from Wuhan city of Chinese Hubei province and rapidly became a global pandemic. Clinical symptoms of the disease range from paucisymptomatic disease to a much more severe disease. Typical symptoms of the initial phase include fever and cough, with possible progression to acute respiratory distress syndrome. Gastrointestinal manifestations such as diarrhoea, vomiting and abdominal pain are reported in a considerable number of affected individuals and may be due to the SARS-CoV-2 tropism for the peptidase angiotensin receptor 2. The intestinal homeostasis and microenvironment appear to play a major role in the pathogenesis of COVID-19 and in the enhancement of the systemic inflammatory responses. Long-term consequences of COVID-19 include respiratory disturbances and other disabling manifestations, such as fatigue and psychological impairment. To date, there is a paucity of data on the gastrointestinal sequelae of SARS-CoV-2 infection. Since COVID-19 can directly or indirectly affect the gut physiology in different ways, it is plausible that functional bowel diseases may occur after the recovery because of potential pathophysiological alterations (dysbiosis, disruption of the intestinal barrier, mucosal microinflammation, post-infectious states, immune dysregulation and psychological stress). In this review we speculate that COVID-19 can trigger irritable bowel syndrome and we discuss the potential mechanisms.  相似文献   

    

Paolo Angelini  Carlo Uribe  Jonathan M. Tobis 《Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital》2021,48(3)

Takotsubo cardiomyopathy (TTC), a persistently obscure dysfunctional condition of the left ventricle, is uniquely transient but nevertheless dangerous. It features variable ventricular patterns and is predominant in women. For 30 years, pathophysiologic investigations have progressed only slowly and with inadequate focus.It was initially proposed that sudden-onset spastic obliteration of coronary flow induced myocardial ischemia with residual stunning and thus TTC. Later, it was generally accepted without proof that, in the presence of pain or emotional stress, the dominant mechanism for TTC onset was a catecholamine surge that had a direct, toxic myocardial effect.We think that the manifestations of TTC are more dynamic and complex than can be assumed from catecholamine effects alone. In addition, after reviewing the recent medical literature and considering our own clinical observations, especially on spasm, we theorize that atherosclerotic coronary artery disease modulates and physically opposes obstruction during spasm. This phenomenon may explain the midventricular variant of TTC and the lower incidence of TTC in men. We continue to recommend and perform acetylcholine testing to reproduce TTC and to confirm our theory that coronary spasm is its initial pathophysiologic factor. An improved understanding of TTC is especially important because of the condition''s markedly increased incidence during the ongoing COVID-19 pandemic.  相似文献   

    

Gianluca Ianiro  Stefano Bibb  Serena Porcari  Carlo Romano Settanni  Federica Giamb  Andreea Roxana Curta  Gianluca Quaranta  Franco Scaldaferri  Luca Masucci  Maurizio Sanguinetti  Antonio Gasbarrini  Giovanni Cammarota 《Gut microbes》2021,13(1)

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Fabio Salvatore Macaluso  Marco Ventimiglia  Walter Fries  Anna Viola  Aldo Sitibondo  Maria Cappello  Barbara Scrivo  Anita Busacca  Antonino Carlo Privitera  Salvatore Camilleri  Serena Garufi  Roberto Di Mitri  Filippo Mocciaro  Nunzio Belluardo  Emiliano Giangreco  Carmelo Bertolami  Sara Renna  Rosalba Orlando  Giulia Rizzuto  Mario Cottone  Ambrogio Orlando   《Journal of gastroenterology and hepatology》2021,36(1):105-111

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Benedetto Mangiavillano  Francesco Auriemma  Mario Bianchetti  Nicola Mantovani  Stefano Pilati  Dario Reggio  Claudio Barletti  Edoardo Forcignan  Giuseppe Pentassuglia  Alberto Arezzo  Elena Cavargini  Carlo Fabbri  Miriam Mezzanzanica  Luca De Luca  Rita Conigliaro  Alessandro Repici 《Digestive endoscopy》2021,33(1):118-124

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Pasquale Vergara MD PhD  Carlo Pignalberi MD  Ennio C. Pisanò MD  Giampiero Maglia MD  Paolo Della Bella MD  Gabriele Zanotto MD  Saverio Iacopino MD  Francesco Solimene MD  Valeria Calvi MD  Massimiliano Marini MD  Massimo Giammaria MD  Mauro Biffi MD  Giovanni Rovaris MD  Fabrizio Caravati MD  Fabio Quartieri MD  Antonio Curnis MD  Antonio Rapacciuolo MD PhD  Gaetano Senatore MD  Stefano Pedretti MD  Davide Saporito MD  Antonio Dello Russo MD  Vincenzo E. Santobuono MD PhD  Patrizia Pepi MD  Antonio Duca MD  Matteo Baroni MD  Giulio Falasconi MD  Daniele Giacopelli MSc  Alessio Gargaro MSc  Antonio D'Onofrio MD 《Journal of cardiovascular electrophysiology》2021,32(9):2528-2535

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Domenico G. Della Rocca MD  Michele Magnocavallo MD  Veronica N. Natale MPH  Carola Gianni MD  PhD  Sanghamitra Mohanty MD  Chintan Trivedi MD  MPH  Carlo Lavalle MD  Giovanni B. Forleo MD  PhD  Nicola Tarantino MD  Jorge Romero MD  Xiadong Zhang MD  Mohamed Bassiouny MD  Amin Al-Ahmad MD  David J. Burkhardt MD  Joseph G. Gallinghouse MD  Javier E. Sanchez MD  Rodney P. Horton MD  Luigi Di Biase MD  PhD  Andrea Natale MD 《Journal of cardiovascular electrophysiology》2021,32(9):2441-2450

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Filippo M. Cauti MD  Pietro Rossi MD  Carmelo La Greca MD  Agostino Piro MD  Natale Di Belardino MD  Alberto Battaglia MD  Federico Ferraris MD  Domenico Pecora MD  Carlo Lavalle MD  Antonio Scalone MD  Luca Rossi MD  Andrea Di Cori MD  Francesco Solimene MD  Roberto Mantovan MD  Stefano Pedretti MD  Luigi Iaia MD  Stefano Bianchi MD  Matteo Anselmino MD 《Journal of cardiovascular electrophysiology》2021,32(5):1296-1304

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