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881.
Anthony?P.?Khawaja Henri?t?Springelkamp Catherine?Creuzot-Garcher Cécile?Delcourt Albert?Hofman René?H?hn Adriana?I.?Iglesias Roger?C.?W.?Wolfs Jean-Fran?ois?Korobelnik Rufino?Silva Fotis?Topouzis Katie?M.?Williams Alain?M.?Bron Gabri?lle?H.?S.?Buitendijk Maria da?Luz?Cachulo Audrey?Cougnard-Grégoire Jean-Fran?ois?Dartigues Christopher?J.?Hammond Norbert?Pfeiffer Angeliki?Salonikiou Cornelia?M.?van?Duijn Johannes?R.?Vingerling Robert?N.?Luben Alireza?Mirshahi Julia?Lamparter Caroline?C.?W.?Klaver Nomdo?M.?Jansonius Paul?J.?Foster On behalf of the European Eye Epidemiology Consortium 《European journal of epidemiology》2016,31(11):1101-1111
Raised intraocular pressure (IOP) is the most important risk factor for developing glaucoma, the second commonest cause of blindness globally. Understanding associations with IOP and variations in IOP between countries may teach us about mechanisms underlying glaucoma. We examined cross-sectional associations with IOP in 43,500 European adults from 12 cohort studies belonging to the European Eye Epidemiology (E3) consortium. Each study conducted multivariable linear regression with IOP as the outcome variable and results were pooled using random effects meta-analysis. The association of standardized study IOP with latitude was tested using meta-regression. Higher IOP was observed in men (0.18 mmHg; 95 % CI 0.06, 0.31; P = 0.004) and with higher body mass index (0.21 mmHg per 5 kg/m2; 95 % CI 0.14, 0.28; P < 0.001), shorter height (?0.17 mmHg per 10 cm; 95 % CI –0.25, ?0.08; P < 0.001), higher systolic blood pressure (0.17 mmHg per 10 mmHg; 95 % CI 0.12, 0.22; P < 0.001) and more myopic refraction (0.06 mmHg per Dioptre; 95 % CI 0.03, 0.09; P < 0.001). An inverted U-shaped trend was observed between age and IOP, with IOP increasing up to the age of 60 and decreasing in participants older than 70 years. We found no significant association between standardized IOP and study location latitude (P = 0.76). Novel findings of our study include the association of lower IOP in taller people and an inverted-U shaped association of IOP with age. We found no evidence of significant variation in IOP across Europe. Despite the limited range of latitude amongst included studies, this finding is in favour of collaborative pooling of data from studies examining environmental and genetic determinants of IOP in Europeans. 相似文献
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Redal Peña MC Pena Pardo FJ Muñoz Iglesias J Crespo-Jara A Rebollo J Brugarolas Masllorens A 《Revista espanola de medicina nuclear》2011,30(4):248-250
(18)F-FDG PET-CT has become an essential tool in oncology patient management. The normal distribution of the FDG and the possible artifacts (pitfalls), including those from CT-based attenuation correction, have already been described in several reviews. However, only a few cases of FDG focal lung uptake have been reported recently. We present two cases of oncology patients during a routine follow-up with this type of pitfall, without morphological correlation in the CT scan. We repeated the study in one of them, which made it possible to verify normalization of the hyperuptake, orienting us towards a possible pitfall. 相似文献
886.
Paula Fernndez‐Ugidos Eduardo Barge‐Caballero Rocío Gmez‐Lpez María J. Paniagua‐Martin Gonzalo Barge‐Caballero David Couto‐Malln Miguel Solla‐Buceta Carmen Iglesias‐Gil Vanesa Aller‐Fernndez Miguel Gonzlez‐Barbeito Jose Manuel Vzquez‐ Rodríguez María G. Crespo‐Leiro 《Transplant infectious disease》2019,21(4)
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Suresh S Ramalingam Pasi A Jänne Tony Mok Kenneth O'Byrne Michael J Boyer Joachim Von Pawel Adam Pluzanski Mikhail Shtivelband Lara Iglesias Docampo Jaafar Bennouna Hui Zhang Jane Q Liang Jim P Doherty Ian Taylor Cecile B Mather Zelanna Goldberg Joseph O'Connell Luis Paz-Ares 《The lancet oncology》2014,15(12):1369-1378
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NC Low E Dugas E O Loughlin D Rodriguez G Contreras M Chaiton J O Loughlin 《BMC psychiatry》2012,12(1):116-10
ABSTRACT: BACKGROUND: Stressful life events are associated with mood disorders in adults in clinical settings. Less described in the literature is the association between common life stressors and a wide range of psychopathology in young adolescents. This study uses a large non-clinical sample of young adolescents to describe the associations among worry or stress about common life events/difficulties, mental health and substance use. METHODS: Data on lifetime stress or worry about common life events/difficulties (i.e., romantic breakups, family disruption, interpersonal difficulties, and personal stress (health, weight, school work)), symptoms of depression, conduct disorder symptoms, and substance use were collected from 1025 grade 7 students (mean age 12.9 years; 45% male). The association between each source of stress and each mental health and substance use indicator was modeled in separate logistic regression analyses. RESULTS: The proportion of adolescents reporting worry or stress ranged from 7% for new family to 53% for schoolwork. Romantic breakup stress was statistically significantly associated with all the mental health and substance use indicators except illicit drug use. Family disruption was statistically significantly associated with depression symptoms, marijuana use, and cigarette use. Interpersonal difficulties stress was statistically significantly associated with depression symptoms. All sources of personal stress were statistically significantly related to depression symptoms. In addition, health-related stress was inversely related to binge drinking. CONCLUSION: Young adolescents may benefit from learning positive coping skills to manage worry or stress about common stressors and in particular, worry or stress related to romantic breakups. Appropriate management of mental health symptoms and substance use related to common stressful life events and difficulties may help reduce emerging psychopathology. 相似文献
890.
Ros B Romero L Ibá?ez G Iglesias S Rius F Pérez S Arráez MA 《Child's nervous system》2012,28(5):691-697