Relapsing polychondritis studied by computed tomography

Computed tomographic findings in a patient with relapsing polychondritis are described. Collapse of the cartilage of the nose and calcification in cartilages of the ears were clearly demonstrated. CT scanning was also helpful in evaluating the tracheobronchial tree for airway compromise, which could prove fatal in this condition.     

Cochlear implantation with implant Combi 40+ produced by MED-El

The paper reports three cases of cochlear implantation using implant Combi 40+ produced by Med-El (Austria). Short-term postoperative testing results demonstrate an appreciable progress in hearing. Changes in speech discrimination and speech production are evaluated.     

The ultrastructural changes in the cellular lining of lymph node sinuses in organochlorine pesticide poisoning

In conditions of exotoxicosis arising after the effect of 2,4-dichlorphenoxyacetic acid cytoplasmic cells of littoral cells of marginal and medullary sinuses undergo alike changes and their cell organelles (rough endoplasmic reticulum, Golgi complex, micropinocytotic vesicles and mitochondria) mass is reduced. These changes are more pronounced in littoral cells of marginal sinus when the dos under the effect of 4 permissible doses of the poison. Intensity of intracellular structures reaction to the toxicant action depends on the cell localization on the lymph passage insid within the lymph node (marginal or medullar sinuses). Dystrophic changes in sinus lining cells so as the speed and character of regenerative processes depend on the dose and time of action of the agent.     

Progesterone for the prevention of preterm birth in women with multiple pregnancies: the AMPHIA trial

Background

Adequate vitamin D concentrations during pregnancy are necessary to neonatal calcium homeostasis, bone maturation and mineralization. The aim of study is to evaluate serum vitamin D concentrations in mothers and their newborns and effect of vitamin D deficiency on pregnancy outcomes.

Methods

552 pregnant women were recruited from Tehran University educating hospitals in the winter of 2002. Maternal and cord blood samples were taken at delivery. The serum was assayed for 25-hydroxyvitamin D3, calcium, phosphorus and parathyroid hormone.

Results

The prevalence of vitamin D deficiency in maternal and cord blood samples were 66.8% and 93.3%, respectively (<35 nmol/l). There was significant correlation between maternal and cord blood serum concentrations of vitamin D. In mothers with vitamin D deficiency, cord blood vitamin D concentrations was lower than those from normal mothers (P = .001). Also, a significant direct correlation was seen between maternal vitamin D intake and weight gain during pregnancy.

Conclusion

Consideration to adequate calcium and vitamin D intake during pregnancy is essential. Furthermore, we think it is necessary to reconsider the recommendation for vitamin D supplementation for women during pregnancy.