全文获取类型
收费全文 | 63322篇 |
免费 | 3091篇 |
国内免费 | 277篇 |
专业分类
耳鼻咽喉 | 853篇 |
儿科学 | 1736篇 |
妇产科学 | 1504篇 |
基础医学 | 8442篇 |
口腔科学 | 1566篇 |
临床医学 | 4677篇 |
内科学 | 15879篇 |
皮肤病学 | 1357篇 |
神经病学 | 5571篇 |
特种医学 | 2133篇 |
外国民族医学 | 6篇 |
外科学 | 7770篇 |
综合类 | 343篇 |
一般理论 | 17篇 |
预防医学 | 6086篇 |
眼科学 | 1046篇 |
药学 | 4272篇 |
中国医学 | 194篇 |
肿瘤学 | 3238篇 |
出版年
2023年 | 353篇 |
2022年 | 633篇 |
2021年 | 1874篇 |
2020年 | 971篇 |
2019年 | 1559篇 |
2018年 | 3377篇 |
2017年 | 2032篇 |
2016年 | 1434篇 |
2015年 | 1419篇 |
2014年 | 2108篇 |
2013年 | 2864篇 |
2012年 | 4115篇 |
2011年 | 4271篇 |
2010年 | 2441篇 |
2009年 | 2143篇 |
2008年 | 3457篇 |
2007年 | 3496篇 |
2006年 | 3320篇 |
2005年 | 3342篇 |
2004年 | 3081篇 |
2003年 | 2907篇 |
2002年 | 2747篇 |
2001年 | 1455篇 |
2000年 | 1542篇 |
1999年 | 1271篇 |
1998年 | 523篇 |
1997年 | 354篇 |
1996年 | 341篇 |
1995年 | 285篇 |
1994年 | 248篇 |
1993年 | 238篇 |
1992年 | 612篇 |
1991年 | 492篇 |
1990年 | 491篇 |
1989年 | 427篇 |
1988年 | 380篇 |
1987年 | 402篇 |
1986年 | 350篇 |
1985年 | 310篇 |
1984年 | 224篇 |
1983年 | 186篇 |
1979年 | 173篇 |
1978年 | 152篇 |
1977年 | 129篇 |
1976年 | 127篇 |
1975年 | 143篇 |
1974年 | 135篇 |
1973年 | 146篇 |
1972年 | 143篇 |
1971年 | 133篇 |
排序方式: 共有10000条查询结果,搜索用时 296 毫秒
91.
92.
93.
José Ignacio Bilbao Mercedes Arias Jesús María Longo Pedro Luis Alejandre María Teresa Betés Arlette María Elizalde 《Cardiovascular and interventional radiology》1997,20(2):149-153
Percutaneous embolization of large portosystemic collaterals was performed in three patients following placement of a transjugular
intrahepatic portosystemic shunt in order to improve hepatopetal portal flow. Improved hepatic portal perfusion was achieved
in these cases, thereby theoretically reducing the risk of chronic hepatic encephalopathy. 相似文献
94.
M. Bergström G. Westerberg G. Németh M. Traut G. Gross G. Greger H. Müller-Peltzer A. Safer S.-Å. Eckernäs A. Grahnér B. Långström 《European journal of clinical pharmacology》1997,52(2):121-128
Objective: The aim of the study was to investigate whether or not esuprone binds substantially to MAO-A in the human brain. Methods: In a randomised double-blind placebo-controlled study 16 male healthy volunteers were examined␣with positron emission tomography
(PET) with [11C]harmine. Eight of the volunteers were given daily doses of 800 mg esuprone, four were given bi-daily doses of 300 mg moclobemide,
and four volunteers were given placebo tablets. PET was performed before initiation of a 7-day treatment period. On day 7,
one investigation was made immediately before administration of the drug, representing 23 h after the previous day's treatment
for esuprone and 11 h after the last tablets of moclobemide. Further investigations were made 4 h and 8 h after the morning
dose on day 7. Results: PET showed a high degree of binding of [11C]harmine, a high-affinity ligand for MAO-A, before the start of treatment, and a marked and similar reduction after treatment
with esuprone and moclobemide. A slight tendency for normalisation of enzyme binding was observed at the last time point.
In the placebo group no change was observed. Plasma kinetics of esuprone showed a rapid elimination with a half-life of about
4 h. Conclusion: The study demonstrates that esuprone was comparable to moclobemide in its effect on MAO-A inhibition in the brain at the
doses given. This is an illustration of the potential of PET to monitor drug effects directly on target biochemical systems
in the brain in human volunteers, and the possibility of using these data, rather than pharmacokinetic data, for the determination
of dosing intervals.
Received: 21 August 1996 / Accepted in revised form: 22 November 1996 相似文献
95.
Prospective study of antigenemia,plasma viremia and lymphocytic viremia in HIV-infected hemophiliacs
S. Melón Garcia M. de Oña Navarro C. Rodriguez Pinto M. Fernández Urgellés A. Martinez Gutierrez P. de la Iglesia F. J. Mendez García 《European journal of clinical microbiology & infectious diseases》1995,14(5):400-405
A total of 186 blood samples from 24 HIV-1 seropositive hemophiliac patients, monitored every four months for 29 months, were investigated for the presence of viral antigen in plasma. In addition, peripheral blood mononuclear cells (PBMC) were cultured for HIV-1, using normal PBMC as a target for replication. Antigenemia was detected in 51 % of the patients and from PBMC in 87.5 % of the patients. The incidence of HIV isolation in asymptomatic patients (42.8 %) was similar to that found in symptomatic patients (51.4 %). Patients with opportunistic infections had a higher incidence of lymphocytic viremia (p<0.05). Plasma viremia was closely associated (p<0.05) with low CD4+ counts and infection progression. The persistence of antigenemia was also a marker of a poor clinical course. In treated patients, plasma viremia was the marker that better correlated with the clinical course, and it did not appear during the first nine months of therapy. Zidovudine doses of >500 mg/day significantly lowered the appearance of antigenemia and lymphocytic viremia (p<0.05). 相似文献
96.
97.
98.
Alberto Rivero Luis Crovetto Lidia Lopez Ricardo Maselli Martín Nogus 《Muscle & nerve》1995,18(9):943-947
We performed single fiber electromyography (SFEMG) in the superior rectus and levator palpebralis (SR-LP) muscles of 17 patients with pure ocular myasthenia gravis (MG) and 9 controls. Thirteen patients were also assessed with SFEMG in the orbicularis oculi (OO) muscle. All the MG patients but none of the control subjects showed abnormal SFEMG jitter in the SR-LP muscles. On the other hand, only 62% of the MG patients had abnormal SFEMG jitter in the OO muscle. The procedure was well tolerated by the patients, and complications were minor. We conclude that SFEMG of the SR–LP muscles is a safe and highly sensitive technique for the diagnosis of ocular MG. © 1995 John Wiley & Sons, Inc. 相似文献
99.
100.
汪国翠 《安徽卫生职业技术学院学报》2003,2(5):83-84
根据笔者在传染科病房工作中的体会,从六个方面针对传染科工作的特殊性和存在的共性分别阐述了传染科护士在工作中如何高标准、严要求自己,如何对病人做到到位的护理,旨在提高传染科病房的整体护理质量,从而把更多的实惠让利于患者。 相似文献