全文获取类型
收费全文 | 1384篇 |
免费 | 162篇 |
国内免费 | 19篇 |
专业分类
儿科学 | 78篇 |
妇产科学 | 4篇 |
基础医学 | 157篇 |
口腔科学 | 64篇 |
临床医学 | 156篇 |
内科学 | 231篇 |
皮肤病学 | 48篇 |
神经病学 | 57篇 |
特种医学 | 245篇 |
外科学 | 130篇 |
综合类 | 53篇 |
预防医学 | 128篇 |
眼科学 | 16篇 |
药学 | 129篇 |
1篇 | |
肿瘤学 | 68篇 |
出版年
2021年 | 6篇 |
2020年 | 10篇 |
2019年 | 13篇 |
2018年 | 15篇 |
2017年 | 7篇 |
2016年 | 13篇 |
2015年 | 33篇 |
2014年 | 40篇 |
2013年 | 49篇 |
2012年 | 30篇 |
2011年 | 28篇 |
2010年 | 60篇 |
2009年 | 59篇 |
2008年 | 36篇 |
2007年 | 44篇 |
2006年 | 34篇 |
2005年 | 47篇 |
2004年 | 28篇 |
2003年 | 39篇 |
2002年 | 24篇 |
2001年 | 32篇 |
2000年 | 21篇 |
1999年 | 26篇 |
1998年 | 86篇 |
1997年 | 82篇 |
1996年 | 61篇 |
1995年 | 57篇 |
1994年 | 43篇 |
1993年 | 51篇 |
1992年 | 32篇 |
1991年 | 36篇 |
1990年 | 20篇 |
1989年 | 53篇 |
1988年 | 54篇 |
1987年 | 36篇 |
1986年 | 26篇 |
1985年 | 24篇 |
1984年 | 22篇 |
1983年 | 23篇 |
1982年 | 22篇 |
1981年 | 20篇 |
1980年 | 18篇 |
1979年 | 13篇 |
1978年 | 19篇 |
1977年 | 13篇 |
1976年 | 13篇 |
1975年 | 14篇 |
1974年 | 5篇 |
1973年 | 5篇 |
1972年 | 4篇 |
排序方式: 共有1565条查询结果,搜索用时 406 毫秒
101.
The psychiatric differentiation of senility and arteriosclerosis 总被引:5,自引:0,他引:5
D P Birkett 《The British journal of psychiatry : the journal of mental science》1972,120(556):321-325
102.
Development of a new access device for transgastric surgery 总被引:10,自引:0,他引:10
Lee?L.?SwanstromEmail author Richard?Kozarek Pankaj?J.?Pasricha Steven?Gross Desmond?Birkett Per-Ola?Park Vahid?Saadat Richard?Ewers Paul?Swain 《Journal of gastrointestinal surgery》2005,9(8):1129-1137
Flexible endoscope-based endoluminal and transgastric surgery for cholecystectomy, appendectomy, bariatric, and antireflux
procedures show promise as a less invasive form of surgery. Current endoscopes and instruments are inadequate to perform such
complex surgeries for a variety of reasons: they are too flexible and are insufficient to provide robust grasping and anatomic
retraction. The lack of support for a retroflexed endoscope in the peritoneal cavity makes it hard to reach remote structures
and makes vigorous retraction of tissues and organs difficult. There is also a need for multiple channels in scopes to allow
use of several instruments and to provide traction/countertraction. Finally, secure means of tissue approximation are critical.
The aim was to develop and test a new articulating flexible endoscopic system for endoluminal and transgastric endosurgery.
A multidisciplinary group of gastrointestinal physicians and surgeons worked with medical device engineers to develop new
devices and instruments. Needs assessments and design parameters were developed by consensus. Prototype devices were tested
using inanimate models until usable devices were arrived at. The devices were tested in nonsurvival pigs and dogs. The devices
were accessed through an incision in the wall of the stomach and manipulated in the peritoneal cavity to accomplish four different
tasks: right upper quadrant wedge liver biopsy, right lower quadrant cecal retraction, left lower quadrant running small bowel,
and left lower quadrant exposure of esophageal hiatus. In another three pigs, transgastric cholecystectomy was attempted.
The positions of the device, camera, and endosurgical instruments, with and without ShapeLock technology, were recorded using
laparoscopy and endoscopy and procedure times and success rates were measured. Instrument design parameters and their engineering
solutions are described. Flexible multilumen guides which could be locked in position, including a prototype which allowed
triangulation, were constructed. Features of the 18-mm devices include multidirectional mid body and/or tip angulation, two
5.5-mm accessory channels allowing the use of large (5-mm) flexible endosurgical instruments, as well as a 4-mm channel for
an ultraslim prototype video endoscope (Pentax 4 mm). Using the resulting devices, the four designated transgastric procedures
were performed in anesthetized animals. One hundred percent of the transgastric endosurgical procedures were accomplished
with the exception of a 50% success for hiatal exposure, a 90% success rate for wedge liver biopsy, and a 33.3% success rate
for cholecystectomy. A new endosurgical multilumen device and advanced instrumentation allowed effective transgastric exploration
and procedures in the abdominal cavity including retraction of the liver and stomach to allow exposure of the gallbladder,
retraction of the cecum, manipulation of the small bowel, and exposure of the esophageal hiatus. This technology may serve
as the needed platform for transgastric cholecystectomy, gastric reduction, fundoplication, hiatus hernia repair, or other
advanced endosurgical procedures.
Presented at the Forty-Sixth Annual Meeting of The Society for Surgery of the Alimentary Tract, Chicago, Illinois, May 14–18,
2005 (oral presentation).
Partially funded and supported by USGI Medical, San Clemente, California. 相似文献
103.
Johnson DB Birkett D Evens C Pickering S 《American journal of health promotion : AJHP》2005,19(6):418-421
PURPOSE: To evaluate a statewide campaign that was designed to reduce television viewing by clients and staff of the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC). Television reduction is frequently recommended as a strategy for preventing pediatric overweight. METHODS: Data were collected from a convenience sample of 10,445 clients and staff who attended clinics during a 3-week period before the intervention and 9188 clients and staff who attended clinics after the intervention. Chi-square tests were used to compare the proportion of WIC clients watching television 2 or 3 hours per day before and after the intervention. Within the context of WIC, which is a large and complex public health program, it was not possible to measure individual exposures or response rates. RESULTS: At baseline, 64.2% of WIC clients reported watching 2 or less hours of television per day. After the intervention, 70.5% limited television viewing to this recommended level. CONCLUSIONS: It is feasible to deliver television-reduction messages in large public health programs. 相似文献
104.
105.
106.
107.
LeRoy AJ; Williams HJ Jr; Bender CE; Segura JW; Patterson DE; Benson RC 《Radiology》1985,155(1):83-85
Two patients had colonic perforation as a result of percutaneous nephrostomy placement followed by track dilatation and renal calculus removal. We present the technical aspects of nephrostomy placement and stone removal, as well as the clinical diagnosis and management of these cases. Both patients recovered well with conservative therapy and required no surgical intervention. This report reviews the anatomic considerations for percutaneous nephrostomy in patients undergoing renal stone removal. 相似文献
108.
SR Mehta VSM HRA Prabhu AJ Swamy Harinder Dhaliwal Dinesh Prasad 《Medical Journal Armed Forces India》2004,60(1):25-27
The varied clinical manifestations and management of 14 male patients with delirium tremens (DT) have been studied. Eight patients were initially hospitalised for diseases unrelated to ethanol abuse i.e. 2 each for gun shot wound, myocardial infarction and stroke, and one each for pneumonia and gastroenteritis. One patient was going through withdrawal because of prodrome of viral hepatitis before he was hospitalised for uncontrolled agitation and delirium. Two known cases of mild essential hypertension on dietary therapy reported for agitation, abnormal behaviour, a single episode of tonic clonic seizure and hypertensive encephalopathy as they could not/did not get alcohol for 3 days. Three patients presented denovo with DT without concomitant illness. The other features besides delirium and hallucinations were tremulousness in 10, tachycardia in 12, fever in 3, diaphoresis in 2 and tonic clonic seizures in 4 patients. The symptoms fluctuated markedly at short intervals and 2 patients did not have any features of sympathetic overactivity. Altered hepatic biochemical parameters and ketonuria with normal blood sugar were noted in 4 and one patients respectively. Other biochemical parameters including serum electrolytes were normal. CT scan brain done for 5 patients revealed subdural haematoma in one. Cerebro spinal fluid (CSF) and EEG findings were noncontributory. All made good recovery with heavy doses of intravenous vitamin B complex, glucose and oral benzodiazepine. Short course of haloperidol was used in 2 patients. Two patients developed pancreatitis during follow up. All patients made complete recovery, and 8 patients have been followed for 8 to 12 months without relapse. The reason for hospitalisation in such cases is often unrelated to alcohol abuse; hence a detailed history of alcoholism is mandatory to identify those at risk as well as for prompt treatment and decreasing the mortality.Key Words: Alcohol withdrawal, Concomitant illnesses, Delirium, Precipitating events 相似文献
109.
Birkett D Johnson D Thompson JR Oberg D 《Journal of the American Dietetic Association》2004,104(8):1277-1280
Supplemental Nutrition Program for Women, Infants, and Children (WIC) families were asked to identify motivators and barriers to health behavior change and preferred approaches to nutrition education in WIC. Six focus groups involved a total of 41 English-speaking WIC participants and addressed parenting, family meals, food preparation, and physical activity. The discussions were audiotaped, transcribed, and analyzed using NUD*IST software (Non-Numerical Unstructured Data Indexing, Searching, and Theorizing, version 4.0. Thousand Oaks, CA: Sage Publications Software, 1997). Key barriers to behavior change included inadequate parenting skills, lack of knowledge, unhealthy social environments, lack of time, and lack of social or financial support. Key motivators included feelings of responsibility, concern for child health and development, and positive social support. Participants identified facilitated discussions, support groups, cooking classes, and a WIC Web site as preferred methods of nutrition education. Results provided the foundation for the Healthy Habits nutrition education modules implemented in the Washington State WIC program and can be used to improve future nutrition education in WIC. 相似文献
110.
Kehely A Bates PC Frewer P Birkett M Blum WF Mamessier P Ezzat S Ho KK Lombardi G Luger A Marek J Russell-Jones D Sönksen P Attanasio AF 《The Journal of clinical endocrinology and metabolism》2002,87(5):1974-1979
The aim of GH replacement therapy in GH-deficient adults is to optimize response with minimum incidence of adverse reactions, but optimal therapy regimens are still to be established. This two-arm parallel study examined effects of two GH dose algorithms in adults with GH deficiency of adult or childhood onset. Patients on low dose (LD; n = 302) received GH at 3 microg/kg per day for 3 months increasing to 6 microg/kg per day for 3 months, and those on conventional dose (CD; n = 293) started on 6 microg/kg per day for 3 months increasing to 12 microg/kg per day for 3 months. The proportion of patients completing therapy was greater for the LD group than the CD group for the first 3 months (93.0% vs. 88.1%; P = 0.037) and overall for the 6 months (90.7% vs. 84.0%; P = 0.013). Both dose groups showed significant increases in lean body mass and decreases in fat mass for all time points. Percent increase in lean body mass was less with LD than CD over the first 3 months (2.43 +/- 4.33 vs. 3.58 +/- 4.69%; P = 0.006) but not overall for the 6-month period (4.38% +/- 5.34% vs. 5.21% +/- 5.99%; P = 0.141). Percent decrease in fat mass was less with LD than CD for the first 3 months (-2.81% +/- 7.81% vs. -5.53% +/- 8.64%; P < 0.001) and overall for the 6-month period (-6.35% +/- 9.42% vs. -9.45% +/- 12.07%; P = 0.006). IGF-I SD score increased less with LD than CD for 0 to 3 and 0 to 6 months, although for IGF-binding protein-3 SD score, there was no significant difference between doses at any time. Arthralgia was the only adverse event that occurred significantly less frequently with LD than with CD. Calculated changes based on gender and onset indicated greater changes in males than females for body composition, but there was little difference in GH-related adverse events between males and females. The lower starting dose with dose titration appeared more favorable, but differences in response between genders and onset of GH deficiency need to be taken into account when setting an individual dose regimen. 相似文献