异丙酚诱导期脑电效应

异丙酚是快速，短效催眠药，对中枢神经系统抑制较轻。ＥＥＧ监测是判断异丙酚诱导期麻醉深度敏感而直接的手段。１８例ＡＳＡⅠ－Ⅱ级患者在注入芬太尼３．６μｇ／ｋｇ１０ｍｉｎ后给予异丙酚２ｍｇ／ｋｇ或硫喷妥钠４ｍｇ／ｋｇ于２０ｓ内缓慢静注，诱导期间用ＳＡＮ－ＥＩ２１Ａ７１脑电图监测仪持续描记脑电变化。结果表明，异丙酚与硫喷妥纳均首先产生β高幅兴奋性活动，最大效应期异丙酚无δ波，维持期效应则相似。起效时间，     

Undesirable effects of drying on articular cartilage]

Knee joints of mature rabbit were exposed to room air (room temperature 23 degrees C, humidity 63.5%) for a period ranging from 30 minutes to hours to imitate the human situation in operating room. The morphological findings indicated that the articular cartilage of the femur trochlea was moderately degenerated after 30 minutes of drying and obvious degeneration occurred two hours after operation. The articular cartilage of the patella also degenerated after two-hour drying. No necrosis was noted in the cartilage of the femoro-tibial joint as that part could not be exposed thoroughly. It was possible to reduce the degenerative changes of articular cartilage if the joint was irrigated with Ringer's solution every 5 minutes. The results indicated that drying, a physical factor, can induce the degeneration of the articular cartilage. The longer the drying time, the more obvious the degenerative changes of cartilage; Ringer's solution is useful to prevent the degenerative changes. Clinically, the following points are worth considering: (1) Operating under arthroscope is much better than arthrotomy in avoiding the degenerative change of the cartilage; (2) The operating time should be as short as possible; (3) It is useful to irrigate the joint with some liquid to keep the joint surface moist; and (4) The consequence of exposure of the joint cartilage in cases of open injury of the joint must be seriously considered.     

Fungal otitis in Libreville. Study of 83 cases

83 cases of mycotic otitis of external ear are reported during a period of 27 months from three departments of otorhinolaryngology in Libreville (Gabon, Central Africa) Prevalence is estimated at about 25% among all infectious otitis. The main functional signs are pruritus, otorrhea, pain and hypoacousia. The physical examination shows masse of white, grey, black or creamy caseous debris, invading the external auditory meatus (EAM) which is sometimes inflammatory. Fungal species responsible of otitis are Aspergillus (54%), yeasts (45%) mainly Candida, infrequently Fusarium (1%). A niger (26%), A. flavus (17%), Candida parapilosis (18%), Candida albicans (9%) are predominant species isolated (70%) among all the 21 species of identified fungi from otomycosis in Gabon. Therapy, done by thorough washing of the ear followed by insertion into the EAM of a wick soaked in Econazole or Amphotericin B, is quickly effective.     

Ultrastructure of hemangio-endothelioma of the bone

Specimens of hemangio-endothelioma of bone from 3 patients were prepared and scrupulously analyzed with light and electron microscopes. The main findings are summarized as follows: (1) The tumour cells are of endothelial nature to form vascular spaces lined with atypical endothelial cells which bulge into the lumen. (2) Most tumour cells have a good number of organellae, especially plasmic vesicles and filaments in cytoplasm. (3) Many tumour cells are closely opposite with bridging granules in between. These features are the differentiating points of hemangio-endothelioma from other bone tumours. The plasmic vesicles are of particular interest in their function which has not yet been made clear. They may either be a structure for transporting large molecular substance including endocytosis, intracytosis and exocytosis, or a temporary storage of membrane or of plasma.     

电针刺激对大鼠渗出液前列腺素E_2和F_(2α)浓度及其比值的影响

本文应用放射免疫法测定了巴豆油诱发大鼠肉芽囊渗出液无细胞上清和炎性白细胞中PGE_2和PGF_2α含量,并探讨了电针刺激对PGE_2和PGF_2α含量及其比值变化的影响,证明电针刺激的抗渗出作用至少与电针刺激降低FGE_2/PGF_2α比值有关。