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排序方式: 共有8539条查询结果,搜索用时 46 毫秒
31.
用9周-39周引产胎儿标本72例,取右耳廓石蜡切片,HE和Weitert弹性纤维染色,光镜观察其弹性软骨、弹性纤维、耳廓肌和结缔组织的发生。 相似文献
32.
显微定量法测定中成药中猪牙皂的含量 总被引:2,自引:0,他引:2
目的 :制定猪牙皂在脐风散与惊风散中的显微定量标准。方法 :用显微定量法 ,以猪牙皂特有的石细胞为显微特征物 ,对脐风散与惊风散中的猪牙皂进行测定。结果 :猪牙皂含量与每毫克特征数呈显著的线性正相关 ,回归方程为 y =61 .42 x -1 .1 0× 1 0 - 3(γ=1 .0 0 ,α=0 .0 5 )。结论 :显微定量法测定脐风散与惊风散中猪牙皂的含量是可行的 ,结果可靠 相似文献
33.
Xin-ping Tang Kang Zeng Guan-hua Chen Long-yan Bi Long-zhong Fan Chang-fa Shao 《第一军医大学学报》2003,23(8):870-872
OBJECTIVE: To investigate the association of Malassezia furfur with chronic urticaria in the crew members of ships. METHODS: A comparative mycological study of 126 crew members of ships with chronic urticaria and 45 normal control subjects was carried out. The 82 urticaria patients identified as positive for Malassezia furfur were divided into groups A and B to receive treatment with antihistaminics (group A) and antihistaminics combined with 2% ketoconazole shampoo(group A). RESULTS: The carrier rates of Malassezia furfur were significantly higher in urticaria patients than in the normal control subjects (P<0.01), but in view of the case ratios of the final cure or improvement, no significant difference was observed between the two groups by the end of the treatment courses (P>0.05). But 6 to 8 weeks from the end of the treatment course, better therapeutic effect was noted in group B (P<0.01), with higher rate of negative Malassezia furfur findings (P<0.01). CONCLUSION: Malassezia furfur may play an important role in the prevalence of chronic urticaria among the crew members, and anti-fungal treatment may produce better long-term therapeutic effect. 相似文献
34.
BACKGROUND: Growing interest is nowadays focused on the quality of life of
elderly people who survive with chronic diseases. Coronary heart disease
(CHD) is one of the most common diseases among the elderly and may have an
unfavourable impact on the patient's emotional well-being. OBJECTIVES: We
aimed to describe the prevalence of depression and the occurrence of
depressive symptoms among elderly CHD patients, with a special emphasis on
the relations between depression and the severity of CHD, and to find out
the possible association between CHD and depression. METHODS: The study was
carried out at the health centre of the municipality of Lieto, in
south-west Finland. The study population consisted of 488
community-dwelling men and 708 women, over 64 years old, from among whom
the participants with CHD (89 men and 73 women) were selected, and for whom
178 male and 146 female sex- and age- matched controls (free of CHD) were
drawn from the population. CHD patients were selected on the basis of the
presence of angina pectoris or a past myocardial infarction. Depressive
symptoms were measured with the Zung Self-rating Depression Scale.
Depression was described in relation to the severity of dyspnoea and chest
pain among patients. The associations between depression and age, health,
health behaviour, drugs, functional ability and social, psychosocial and
environmental factors were analysed by logistic regression analyses.
RESULTS: The prevalence of depression was 29% among male patients and 20%
among female patients. Depression was significantly more common among male
CHD patients than among male controls (P = 0.011). Among women, depression
was not associated with CHD. Earlier, depression had gone undiagnosed among
many CHD patients and controls, especially male patients. Among male CHD
patients, depression was associated with more severe dyspnoea, but no
similar association was found among female CHD patients. Among men the
occurrence of CHD, physical disability, widowhood or divorce, and among
women previous clinical depression, physical disability and the use of
angiotensin-converting enzyme (ACE) inhibitors, were associated with
depression. CONCLUSION: Depression is common among patients with CHD. It
seems that CHD is not an independent factor in the aetiology of depression
among the elderly. The association of CHD with depression among men is
explained by the acute or chronic psychic stress caused by CHD. It may be
that the more complicated the patient's CHD, the more probable is the
presence of depression.
相似文献
35.
用鸡胚卵黄囊分离斑点热群立克次体的研究 总被引:7,自引:0,他引:7
本文在用传统的实验动物感染法分离立克次体同时,并尝试用鸡胚卵黄囊培养法直接分离立克次体。结果:用前者未分离出立克次体,而用后者分别从来自北京昌平县的中华革蜱和来自黑龙江省虎林县的嗜群血蜱中各分离到1株立克次体。经鉴定,这两株立克次体属于斑点热群立克次体。结论:鸡胚卵黄囊培养法可以直接从现场节肢动物标本中分离病原体。 相似文献
36.
自体皮源奇缺条件下瘢痕挛缩畸形的晚期临床修复 总被引:11,自引:6,他引:5
目的寻找对烧伤后畸形伴自体皮源奇缺患进行晚期修复的新方法。方法5例特重度、特大面积烧伤患治愈后伴较严重畸形,且自体皮源奇缺。采用柔软成熟的瘢痕皮肤作为修复的皮源,用扩张器扩张瘢痕皮肤后,切取中厚瘢痕皮片进行修复;不宜行瘢痕皮肤扩张术时,切取刃厚瘢痕皮片与异体脱细胞真皮基质组成复合皮进行修复。观察两种方法的疗效。结果所移植的扩张瘢痕皮片和复合皮均成活,功能和外形恢复良好,远期疗效近似正常自体中厚皮移植。结论采用不同厚度的瘢痕皮片修复烧伤畸形是可行的,可扩大自体皮源。此法对于皮源奇缺的瘢痕患尤其适用。 相似文献
37.
IS Park H Kiyomoto F Alvarez YC Xu HE Abboud SL Abboud 《American journal of kidney diseases》1998,32(6):1000-1010
The renal insulin-like growth factor-I (IGF-I) system has been implicated in the pathogenesis of renal hypertrophy, altered hemodynamics, and extracellular matrix expansion associated with early diabetes. The relative abundance of IGF binding proteins (IGFBPs) in the renal microenvironment may modulate IGF-I actions. However, the precise IGFBPs expressed in the glomerular and tubulointerstitial compartments during diabetic renal growth have not been characterized. In the present study, in situ hybridization studies were performed to examine the expression of IGFBP-1 to -6 messenger RNAs (mRNAs) 3, 7, and 14 days after streptozotocin (STZ) injection in rats. In control, nondiabetic kidneys, all six IGFBP mRNAs were differentially expressed with a predominance of IGFBP-5. The onset of renal hypertrophy in STZ-induced diabetes was associated with a rapid and site-specific induction of IGFBP-1, -3, and -5 mRNAs. In contrast, basal expression of IGFBP-2, -4, and -6 mRNAs was not altered in diabetic rats. IGFBP-5 mRNA expression increased in diabetic glomeruli, cortical, and inner medullary peritubular interstitial cells at days 3, 7, and 14. Although normal glomeruli failed to express IGFBP-3, it was induced concomitantly with IGFBP-5 in diabetic glomeruli and cortical peritubular interstitial cells. IGFBP-1 mRNA levels also increased in cortical tubular cells at each time point tested. Peak induction of IGFBP-3 and -5 was observed at day 3, whereas IGFBP-1 was delayed until day 7. IGFBP-1, -3, and -5 mRNA levels declined by day 14, but remained persistently elevated above control. By immunoperoxidase staining, similar alterations in the pattern of IGFBP-3 and -5 protein expression were observed at each time point. The preferential and site-specific increase in IGFBP-1, -3, and -5 suggest that these IGFBPs may regulate the local autocrine and/or paracrine actions of IGF-I and contribute to the pathogenesis of the early manifestations of diabetic nephropathy. 相似文献
38.
自体造血干细胞移植治疗恶性血液病 总被引:2,自引:0,他引:2
为探讨恶性血液病的有效治疗方法,应用自体骨髓移植(ABMT)38例,自体外周血造血干细胞移植(ABSCT)13例,自体外周血造血干细胞与自体骨髓联合移植15例。治疗白血病54例,恶性淋巴瘤11例,多发性骨髓瘤1例。外周血造血干细胞采用化疗加多抗甲素或C—CSF动员。移植物采用微波、阿克拉霉素净化处理。结果:两组动员方案均有良好动员效果。ABSCT组及联合移植组造血功能恢复比ABMT组快(P<0.05),合并症少。66例中,45例仍呈持续缓解(CCR),中位CCR时间32(5~98)个月,复发21例。3年无病生存率及复发率分别为68.5%及26.1%。结果表明:自体造血干细胞移植是根治恶性血液病的有效手段。ABSCT及联合移植具有造血功能恢复快,合并症少等优点。微波和阿克拉霉素体外净化移植物是一种简便、有效的净化方法。 相似文献
39.
40.
目的 探讨右美托咪定调控核因子E2相关因子2(Nrf2)/血红素加氧酶1(HO-1)通路对过氧化氢(H2O2)诱导心肌细胞氧化应激损伤的作用。方法 体外培养大鼠H9C2心肌细胞,设置对照组、H2O2组、1μmol右美托咪定+H2O2组、5μmol右美托咪定+H2O2组、10μmol右美托咪定+H2O2组。CCK-8法检测各组H9C2细胞增殖情况;酶联免疫吸附试验(ELISA)检测各组H9C2细胞丙二醛(MDA)、超氧化物歧化酶(SOD)水平;实时荧光定量聚合酶链反应(q RT-PCR)检测各组H9C2细胞Nrf2、HO-1 mRNA相对表达量;Western blotting检测各组H9C2细胞Nrf2、HO-1蛋白相对表达量。结果 与对照组比较,H2O2组H9C2细胞存活率、SOD水平、Nrf2、HO-1 mRNA及蛋白相对... 相似文献