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We describe a middle-aged Chinese systemic lupus erythematosus (SLE) patient developing steroid refractory and transfusion dependent red cell aplasia. Oral danazol 200 mg twice per day was started together with low-dose prednisolone therapy. There was no further recurrence of anemia 1 month after this combined therapy. 相似文献
37.
Forty patients that received prosthetic appliances as part of dental treatment were interviewed about satisfaction with the apparatus. The opinions of the guardians were also considered. The majority of children had complained about missing teeth, but even a greater percentage expressed satisfaction during wear of the prosthetic appliance. Among the guardians, only one of them expressed dissatisfaction with the appliance design. Rehabilitation plan should be discussed with children and guardians considering their perceptions and adequate indications for each case. 相似文献
38.
Oliveira LM Primo LG Barcelos R Portela MB Bastos EP 《ASDC journal of dentistry for children》2002,69(2):175-9, 125
The purpose of this report was to describe the radiographic findings of 6 uncommon situations of supernumerary teeth in a Brazilian pediatric dentistry and orthodontic clinic. Six cases of supernumerary teeth were diagnosed in association with other dental anomalies such as number, position, and form. The supernumeraries were asymptomatic and were detected through routine radiographic examination. The importance of routine radiographic examination is emphasized for the correct diagnosis of supernumerary teeth, and avoidance of associated complications. 相似文献
39.
Jin X Xia L Wang LS 《上海交通大学学报(医学版)》2007,27(11):1316-1316
Although cardiac hypertrophy in hypertension has been well recognized, the molecular mechanisms for the development of hypertrophy are still largely unknown. In this study, the protein expression profiles of left ventricular myocardia in spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) rats at different ages were analyzed using 2-DE in combination with MALDI-TOF/TOF MS/MS. The results showed that 20 proteins were modulated in the hypertrophic myocardium. Out of these modulated proteins, 13 proteins presented significant changes in SHR at an early stage prior to the development of sustained hypertension, while the changes of the other 7 protein expres- sions occurred only at a late stage in SHR when the blood pressure was significantly elevated, and were largely reversible by treatment with rennin-angiotensin-aldosterone system inhibitors losartan or enalapril. These data demonstrate that the changes in energy metabolism in the hypertrophied heart favor an increase in glycolysis and a decrease in oxidation of fatty acid and glucose, which occur at an early stage in SHR without hypertension. Our results also provide evidence to support the hypothesis that oxidative stress plays an important role in the development of hypertensive cardiac hypertrophy. 相似文献
40.
N Yang SM Liu LF Zheng T Ji Y Li XL Mi H Xue W Ren JD Xu XH Zhang LS Li Y Zhang JX Zhu 《British journal of pharmacology》2010,159(8):1623-1625