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排序方式: 共有212条查询结果,搜索用时 16 毫秒
61.
Lommen CM Pasman JW van Kranen VH Andriessen P Cluitmans PJ van Rooij LG Bambang Oetomo S 《Acta paediatrica (Oslo, Norway : 1992)》2007,96(5):674-680
AIM: To develop and evaluate an algorithm for the automatic screening of electrographic neonatal seizures (ENS) in amplitude-integrated electroencephalography (aEEG) signals. METHODS: CFM recordings were recorded in asphyxiated (near)term newborns. ENS of at least 60 sec were detected based on their characteristic pattern in the aEEG signal, an increase of its lower boundary. The algorithm was trained using five CFM recordings (training set) annotated by a neurophysiologist, observer1. The evaluation of the algorithm was based on eight different CFM recordings annotated by observer1 (test set observer 1) and an independent neurophysiologist, observer2 (test set observer 2). RESULTS: The interobserver agreement between observer1 and 2 in interpreting ENS from the CFM recordings was high (G coefficient: 0.82). After dividing the eight CFM recordings into 1-min segments and classification in ENS or non-ENS, the intraclass correlation coefficient showed high correlations of the algorithm with both test sets (respectively, 0.95 and 0.85 with observer1 and 2). The algorithm showed in five recordings a sensitivity > or = 90% and approximately 1 false positive ENS per hour. However, the algorithm showed in three recordings much lower sensitivities: one recording showed ENSs of extremely high amplitude that were incorrectly classified by the algorithm as artefacts and two recordings suffered from low interobserver agreement. CONCLUSION: This study shows the feasibility of automatic ENS screening based on aEEG signals and may facilitate in the bed-side interpretation of aEEG signals in clinical practice. 相似文献
62.
Periosteal ganglia: CT and MR imaging features 总被引:8,自引:0,他引:8
63.
Michael J. O'Neill Bambang Tridjaja Matthijs J. Smith Katrina M. Bell Garry L. Warne Andrew H. Sinclair 《Human mutation》1998,11(4):340-342
Kallmann syndrome is an inherited disease which is characterised by anosmia (inability to smell) and hypogonadotropic hypogonadism both of which are thought to occur as a result of a failure of correct neuronal migration. To date the only genetic lesions identified are mutations in the X-linked gene, KAL. We conducted a mutation screen of the KAL gene in a family with Kallmann syndrome. This identified a new mutation in the KAL gene which removed an acceptor site at the junction of exon 6 /intron 5. Exon 6 of the KAL gene encodes the C-terminal portion of a fibronectin type III domain may be involved in axonal pathfinding. We presume that the described mutation would result in the removal of exon 6 resulting in a frame shift which terminates the protein prematurely. It has been proposed that both mental illness and vesico-ureteric reflux are associated with mutations in the KAL gene. However, results from the family presented here do not show an association between either trait and the KAL gene mutation. 相似文献
64.
Richard D. Semba Bambang Susatio Muhilal Natadisastra Gantira Natadisastra 《International ophthalmology》1995,19(1):39-42
Xerophthalmia due to vitamin A deficiency is a leading cause of blindness in children and has been a serious problem in Indonesia. To determine whether progress has been made in the eradication of xerophthalmia, we assessed hospital admissions for xerophthalmia at Cicendo Eye Hospital, Bandung, Indonesia. The hospital admission registry from 1981 to 1992 was reviewed. Between January 1981 and December 1992, there were 117 admissions for xerophthalmia, and of these, 63 were boys and 54 were girls, with an average age of 3.9 ± 0.3 years. Hospital admissions for xerophthalmia declined steeply from 1981 to 1985, with a few rare cases from 1985 through 1992. During the same period from 1981 through 1992, there were no overall changes in total hospital admissions or total pediatric admissions. These results suggest that xerophthalmia is becoming less common in Indonesia. 相似文献
65.
Fatal ureaplasmal pneumonia and sepsis in a newborn infant 总被引:5,自引:0,他引:5
F. Brus W. M. van Waarde C. Schoots S. Bambang Oetomo 《European journal of pediatrics》1991,150(11):782-783
Ureaplasma urealyticum was isolated in pure culture from blood tracheal aspirate and lung tissue in a newborn infant, who died of a severe pneumonia within 48h after birth. The clinical course was characterized by persistent pulmonary hypertension of the newborn (PPHN). Post-mortem examination revealed extensive hyaline membrane formation combined with signs of inflammation in both lungs. The clinical and histopathological picture resembled that of early onset group B haemolytic streptococcal pneumonia/sepsis. 相似文献
66.
67.
Ryan Nussbaum Christopher Kelly Eleanor Quinby Ami Mac Bambang Parmanto Brad E. Dicianno 《Archives of physical medicine and rehabilitation》2019,100(1):115-127
Objective
To conduct systematic review to better define how medical mobile applications (apps) have been used in environments relevant to physical medicine and rehabilitation.Data Sources
PUBMED, IEEE, ACM Digital Library, SCOPUS, INSPEC, and EMBASE.Study Selection
A 10-year date limit was used, spanning publication dates from June 1, 2006, to June 30, 2016. Terms related to physical medicine and rehabilitation as well as mobile apps were used in 10 individual search strategies.Data Extraction
Two investigators screened abstracts and applied inclusion and exclusion criteria. Full-length articles were retrieved. Duplicate articles were removed. If a study met all criteria, the article was reviewed in full.Data Synthesis
Specific variables of interest were extracted and added to summary tables. Summary tables were used to categorize studies according themes, and a list of app features was generated.Conclusions
The search yielded abstracts from 8116 studies, and 102 studies were included in the systematic review. Approximately one-third of the studies evaluated apps as interventions, and the remaining two-thirds of the studies assessed functioning of the app or participant interaction with the app. Some apps may have positive benefits when used to deliver exercise or gait training interventions, as self-management systems, or as measurement tools.Registration
The protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) network (no. CRD42016046672). 相似文献68.
Vitamin D as a part of the endocrine system is an important component in the interaction between the kidney, bone, parathyroid hormone, and the intestine, which maintains extracellular calcium level within normal limits, in order to keep the vital physiologic process and skeletal integrity. Vitamin D is also associated with hypertension, muscular function, immunity, and ability to encounter infection, autoimmune disease, and cancer. The role of vitamin D in immunity is a feedback reaction of paracrine to eliminate inflammation or to influence CD4 T-cell differentiation and or to increase the function of T suppressor cell or combination between both. The active form of vitamin D produces and maintains self immunologic tolerance, some studies show that 1,25(OH)2D inhibits induction of disease in autoimmune encephalomyelitis, thyroiditis, type-1 diabetes mellitus, inflammatory bowel disease (IBD), systemic lupus erythematosus, and collagen-induced arthritis and Lyme arthritis. 相似文献
69.
70.
Systemic lupus erythematosus (SLE) has numerous manifestations. Haematology is the common system influenced by the disease. The antibody antiphospholipid syndrome, secondary hematology disorder in SLE, is related to high incidence of thrombosis. The thrombosis events like myocardial infarction and stroke are high in mortality. We reported a-36-year old woman treated for lung tuberculosis (TB) with secondary infection, nephritis lupus, and pancytopenia. The general condition has improved and the patient was planned to discharge while she suddenly fell down, unconscious and had seizure. The CT-scan showed an area of hypodensity on the left thalamus. Haematology results showed high level of fibrinogen and D-dimer as the signs of thrombosis. The anticardiolipin antibody was intermediately positive for IgG and IgM, but lupus anticoagulan was weakly positive. The serial test within 2 months still showed positive IgG. The patient received supportive treatment, heparinization, neurotropic drugs and anticonvulsant. She was discharged in good condition while continuing oral anticoagulant to prevent recurrent seizure. 相似文献