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71.
Using CollaboRATE,a brief patient‐reported measure of shared decision making: Results from three clinical settings in the United States 下载免费PDF全文
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To optimally demonstrate the value of risk management, our actions must show the benefits. The American Society for Healthcare Risk Management (ASHRM) board needs to provide support through tools and resources. ASHRM members must show through their actions the value of risk management. And ASHRM members need to show the organization where actions and activities should be focused in the future. Actions show the value of enterprise risk management. 相似文献
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T Balayan J Begovac A Skrzat‐Klapaczyska I Aho I Alexiev P Bukovinova D Salemovic D Gokengin A Harxhi T Holban D Jevtovic K Kase B Lakatos I Latysheva R Matulionyte C Oprea A Papadopoulos N Rukhadze D Sedlacek J Tomazic A Vassilenko M Vasylyev A Verhaz N Yancheva O Yurin A Horban JD Kowalska 《HIV medicine》2021,22(1):67-72
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María Martínez García Pablo Trincado Aznar Leticia Pérez Fernández Isabel Azcona Monreal María Elena López Alaminos Javier Acha Pérez Ramón Albero Gamboa 《Nefrología : publicación oficial de la Sociedad Espa?ola Nefrologia》2019,39(1)
Introduction
Both dietary restriction of sodium chloride (NaCl) and treatment with thiazides have been used in hypercalciuric patients.Objectives
To calculate regular salt intake and investigate the correlation between natriuresis and urinary calcium with usual diet (B) and after changing the amount of NaCl intake and administration of thiazides.Material and methods
Nineteen healthy young individuals had their diet replaced by 2 l of Nutrison® Low Sodium (500 mg sodium/day) daily for two days. Then, 5 g of NaCl were added every two days («5», «10» and «15»), administering 50 mg (H50) and 100 mg (H100) of Higroton® on the last two days. Blood sodium, plasma renin activity (PRA) and aldosterone were determined in venous blood samples, as were urinary sodium and calcium. Statistical analysis: Wilcoxon t-test and the Pearson linear correlation were calculated.Results
Urinary Na (mEq/24 h): 210.3 ± 87.6 («B»); 42.7 ± 20.4 («5»); 135.5 ± 50.6 («10»); 225.5 ± 56.7 («15»). Urinary calcium (mg/24 h): 207.8 ± 93.6 («B»); 172.8 ± 63.1 («5»); 206.2 ± 87.7 («10»); 227.4 ± 84.1 («15»). A positive correlation was observed between natriuresis and urinary calcium in «10» (r = 0.47) and «15» (r = 0.67). After Higroton®, natriuresis: 232.3 ± 50.7; 377 ± 4 (H50); 341.1 ± 68.4 (H100); Ca in urine: 209.8 ± 57.4; 213.2 ± 67.6 (H50); 159.1 ± 52.2 (H100).Conclusions
Salt intake in the population studied was estimated to be 14.9 ± 4.9 g/day with a positive correlation found between sodium and calcium urine output with daily intakes of 11.25 and 16.25 g of salt. With the usual intake, for each gram of salt, urinary calcium increased by 5.46 mg/24 h and with 100 mg of Higroton® it decreased by 50.7 mg/24 h. These data could be useful for the management of patients with excretory hypercalciuria or hypoparathyroidism. 相似文献80.
Interleukin-4 (IL-4) is a potent mediator of growth and differentiation of cells of several hematopoietic lineages. Interleukin-5 (IL-5) is a lineage-specific hematopoietic growth factor that stimulates the production of eosinophils and eosinophil colonies from normal human bone marrow cells. By using somatic cell hybrids and in situ chromosomal hybridization, we localized the IL-4 and IL-5 genes to human chromosome 5 at bands q23-31, a chromosomal region that is frequently deleted [del(5q)] in patients with myeloid disorders. By in situ hybridization, the IL-4 and IL-5 genes were found to be deleted in the 5q- chromosome of four patients with refractory anemia (RA) or therapy-related acute nonlymphocytic leukemia (t-ANLL), who had a del(5q). Thus a small segment of chromosome 5 contains IL-4, IL-5, IL- 3, and GM-CSF as well as other genes such as CD14 and EGR1. Our findings that each of these genes was deleted in the 5q- chromosome suggest that loss of function of one or more of these genes may play an important role in the pathogenesis of hematologic disorders associated with a del(5q). 相似文献