全文获取类型
收费全文 | 459篇 |
免费 | 37篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 10篇 |
妇产科学 | 22篇 |
基础医学 | 85篇 |
口腔科学 | 5篇 |
临床医学 | 39篇 |
内科学 | 81篇 |
皮肤病学 | 12篇 |
神经病学 | 49篇 |
特种医学 | 6篇 |
外科学 | 78篇 |
综合类 | 6篇 |
预防医学 | 22篇 |
眼科学 | 13篇 |
药学 | 32篇 |
中国医学 | 6篇 |
肿瘤学 | 25篇 |
出版年
2023年 | 8篇 |
2022年 | 35篇 |
2021年 | 24篇 |
2020年 | 8篇 |
2019年 | 26篇 |
2018年 | 26篇 |
2017年 | 13篇 |
2016年 | 21篇 |
2015年 | 21篇 |
2014年 | 24篇 |
2013年 | 28篇 |
2012年 | 38篇 |
2011年 | 27篇 |
2010年 | 20篇 |
2009年 | 11篇 |
2008年 | 21篇 |
2007年 | 19篇 |
2006年 | 20篇 |
2005年 | 19篇 |
2004年 | 16篇 |
2003年 | 14篇 |
2002年 | 7篇 |
2001年 | 5篇 |
2000年 | 4篇 |
1999年 | 6篇 |
1998年 | 1篇 |
1997年 | 2篇 |
1996年 | 1篇 |
1995年 | 1篇 |
1994年 | 3篇 |
1993年 | 1篇 |
1992年 | 5篇 |
1991年 | 1篇 |
1990年 | 4篇 |
1989年 | 3篇 |
1988年 | 1篇 |
1987年 | 3篇 |
1986年 | 5篇 |
1985年 | 1篇 |
1984年 | 2篇 |
1981年 | 1篇 |
1979年 | 1篇 |
排序方式: 共有497条查询结果,搜索用时 31 毫秒
41.
Imran Ali Changsheng Peng Iffat Naz Dichu Lin Devendra P. Saroj Mohsin Ali 《RSC advances》2019,9(7):3625
Novel bio-magnetic membrane capsules (BMMCs) were prepared by a simple two-step titration-gel cross-linking method using a polyvinyl alcohol (PVA) and sodium alginate (SA) matrix to control the disintegration of phytogenic magnetic nanoparticles (PMNPs) in an aqueous environment, and their performance was investigated for adsorbing cationic malachite green (MG) dye from water. The prepared BMMCs were characterized by FTIR, powder XRD, SEM, EDX, XPS, VSM and TGA techniques. The findings revealed that the hysteresis loops had an excellent superparamagnetic nature with saturation magnetization values of 11.02 emu g−1. The prepared BMMCs not only controlled the oxidation of PMNPs but also improved the adsorptive performance with respect to MG dye (500 mg g−1 at 298.15 K and pH 6.5) due to the presence of a large amount of hydrophilic functional groups (hydroxyl/–OH and carboxyl/–COOH) on/in the BMMCs. The smooth encapsulation of PMNPs into the PVA–SA matrix established additional hydrogen bonding among polymer molecular chains, with improved stability, and adsorptive performance was maintained over a wide range of pH values (3–12). Importantly, the prepared BMMCs were easily regenerated just by washing with water, and they could be re-utilized for up to four (4) consecutive treatment cycles without observing any apparent dissolution of iron/Fe0 or damage to the morphology. According to the mass balance approach, an estimated amount of 100 mL of treated effluent can be obtained from 160 mL of MG dye solution (25 mg L−1) just by employing a 0.02 g L−1 adsorbent dosage. Finally, a model of BMMCs based on zero-effluent discharge was also proposed for commercial or industrial applications. The prepared BMMCs are greatly needed for improving the water/wastewater treatment process and they can be utilized as an excellent adsorbent to remove cationic pollutants for various environmental applications.Novel bio-magnetic membrane capsules were prepared by a simple two-step titration-gel cross-linking method using a polyvinyl alcohol and sodium alginate matrix to control the disintegration of phytogenic magnetic nanoparticles in aqueous media. 相似文献
42.
Qurrat-ul-Ain Jaweria Khatoon Muhammad Raza Shah Muhammad Imran Malik Iffat Abdul Tawab Khan Sumaira Khurshid Raheela Naz 《RSC advances》2019,9(6):2978
This study was aimed at developing green histidine-modified Fe3O4 nanoparticles (His-MNPs) for the adsorptive removal of Acid Black 1 (AB1) from aqueous solution. The His-MNPs were characterized by atomic force microscopy, scanning electron microscopy-energy dispersive X-ray spectrometry, infra-red spectra and thermogravimetry. These MNPs were spherical (average diameter 11–28 nm) with polydispersity index of 1.40 and about 13% mass coating of histidine. To optimize AB1 adsorption on His-MNPs and understand its mechanism, the influences of different operational variables (pH, adsorbent amount, temperature, initial AB1 concentration, contact time, ionic strength, etc.) on adsorption were examined with adsorption isotherms, kinetics and thermodynamic studies. The AB1 adsorption from water was fast with equilibrium time ≤ 45 min. The adsorption equilibrium was best fitted to the Langmuir isotherm model (qmax = 166.7 mg g−1 at the adsorbent dose of 0.2 g L−1, temperature 30 °C and pH 4). The linearity order for other isotherms was as follows: Dubinin–Radushkevich (D–R) < Temkin < Freundlich. The kinetics of the AB1 adsorption demonstrated the best compliance with the pseudo-second-order model, predominantly controlled by film diffusion as compared to intraparticle diffusion. Thermodynamic parameters (ΔH° and ΔG°) reflected the exothermic and spontaneous adsorption process. The values of ΔG°, ΔH°, activation energy and D–R free adsorption energy were all consistent with the physisorptive removal of AB1. The spectral (electronic and IR) and pH studies further corroborated the mechanism of AB1 removal by His-MNPs. The His-MNPs showed efficient adsorption, easy regeneration and excellent reusability, assisted by their pH-responsive properties. The prepared adsorbent can provide a safe, effective and economical alternative strategy for removing azo dyes from wastewater.Effective and eco-friendly separation of Acid Black 1 dye from water by electrostatic adsorption onto reusable Histidine-Fe3O4 nanoparticles, credited to their pH-responsiveness. 相似文献
43.
44.
45.
46.
47.
Yakoob J Abbas Z Beg MA Jafri W Naz S Khalid A Khan R 《Epidemiology and infection》2012,140(10):1773-1779
We determined the prevalence of microsporidia Enterocytozoon (Ent.) bieneusi and Encephalitozoon (E.) intestinalis infection in patients with chronic diarrhoea and hepatocellular carcinoma (HCC). A total of 330 stool samples were examined from 171 (52%) patients with chronic diarrhoea, 18 (5%) with HCC while 141 (43%) were controls. Stool microscopy, polymerase chain reaction (PCR) with species-specific primers for Ent. bieneusi and E. intestinalis and sequencing were carried out. Microsporidia were found by trichrome staining in 11/330 (3%) and E. intestinalis by PCR in 13/330 (4%) while Ent. bieneusi was not detected. PCR for E. intestinalis was positive in 8/171 (5%) stool samples from patients with chronic diarrhoea, 2/141 (1·4%) samples from healthy controls and in 3/18 (17%) samples from patients with HCC. In the chronic diarrhoea group, E. intestinalis was positive in 4/171 (2·3%) (P=0·69) stool samples compared to 2/18 (11%) (P=0·06) in the HCC group and 2/141 (1·4%) from healthy controls. E. intestinalis infection was significantly associated with chronic diarrhoea and HCC in these patients who were negative for HIV. Stool examination with trichrome or species-specific PCR for microsporidia may help establish the cause of chronic diarrhoea. 相似文献
48.
Aykin N Cevik F Demirturk N Demirdal T Orhan S Naz H 《Scandinavian journal of infectious diseases》2008,40(6-7):533-537
We investigated the seroprevalence of HCV in stable sexual partners and offspring of chronic hepatitis C patients, and aimed to determine the risk factors involved. 191 anti-HCV and HCV RNA positive subjects who coinhabited with their spouse and/or offspring were included. Risk factors of index cases for disease transmission, liver biopsy results, anti-HCV and HCV-RNA in spouses and/or offspring were evaluated. Together with index cases, a total of 404 family members including 174 stable sexual partners and 230 offspring were included. The most common risk factors among index cases were dental procedures (73.8%), history of surgery (64.9%), and blood transfusions (24.1%). Anti-HCV positivity was established in 11 (2.7%) of the total 404 family contacts--6 sexual partners and 5 offspring. HCV seropositivity was significantly higher in the spouses of index cases with severe hepatitis C compared to those with mild to moderate hepatitis C (p=0.008), but there was no statistically significant correlation between the severity of liver disease in index cases and anti-HCV positivity in their offspring. In conclusion, anti-HCV seropositivity in the spouses and children of patients who are HCV-RNA positive HCV carriers does not appear to be higher than the HCV seroprevalence in our country. 相似文献
49.
50.
Ham's F-10 medium was analyzed biochemically before and after growth of murine and human embryos. Ham's F-10 medium (280 mosm/kg, pH 7.4) alone, by means of reverse-phase high-performance liquid chromatography, demonstrated one major hydrophilic peak, which eluted at 4 to 8 minutes in a 10% to 48% acetonitrile gradient. This peak showed a single peptide of 50 kilodaltons in one-dimensional polyacrylamide gel electrophoresis and size exclusion high-performance liquid chromatography. After the growth of two-cell murine embryos to eight-cell embryos or blastocysts, the major hydrophilic peak was greatly reduced or absent in the culture medium, and in turn a major hydrophobic peak appeared that eluted at 29 minutes. The major hydrophobic peak could not be focused in one-dimensional polyacrylamide gel electrophoresis, but a high content of polar and nonpolar amino acids was revealed in N-terminal sequencing and mass spectrometric analysis. This shift in the peaks was not detected when embryos were cultured in the presence of 0.02% sodium azide. In vitro culture of human zygotes from the pronuclear stage to two to eight cells caused a similar disappearance of the major hydrophilic peak concomitant with the appearance of one to three major hydrophobic peaks in the culture medium. We conclude that the change in profile of culture medium from hydrophilic to hydrophobic peaks on high-performance liquid chromatography is indicative of the metabolic pattern of murine and human embryos. These data also indicate that murine and human embryos do not secrete any major peptide during their development in vitro. 相似文献